2-methyl-1-(4-morpholinophenyl)-2-morpholinopropan-1-one | 97458-99-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-methyl-1-(4-morpholinophenyl)-2-morpholinopropan-1-one
• 英文别名: 2-methyl-2-morpholin-4-yl-1-(4-morpholin-4-ylphenyl)propan-1-one
• CAS: 97458-99-6
• 化学式: C₁₈H₂₆N₂O₃
• 分子量: 318.416
• InChiKey: FFZCJGPYMRPBIR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.61
• 拓扑面积：
  42
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  2-methyl-1-(4-morpholinophenyl)-2-morpholinopropan-1-one 以 various solvent(s) 为溶剂， 生成 2-N-morpholino-2-propyl radical 、 4-morpholinobenzoyl radical
  参考文献：
  名称：

  EPR studies on the photofragmentation of 2,2-dialkyl-2-alkylaminoacetophenones

  摘要：

  Free radical reactions induced by photolysis of 2,2-dialkyl-2-alkylaminoacetophenone photocuring agents have been studied by continuous wave (CW) and time-resolved EPR spectroscopy. In all solvents alpha-cleavage from the triplet state is the major process. In hydrogen donor solvents it is accompanied by photoreduction followed by a rapid amine elimination from the ketyl radical intermediate. The benzoyl and alpha-aminoalkyl radicals resulting from alpha-cleavage readily add to acrylonitrile whereas radicals formed by photoreduction do not.

  DOI：

  10.1039/p29920000513
• 作为产物：
  描述：

  2-chloro-4'-fluoroisobutyrophenone 以 甲醇 、 水 为溶剂， 反应 73.0h， 生成 2-methyl-1-(4-morpholinophenyl)-2-morpholinopropan-1-one
  参考文献：
  名称：

  一种2-甲基-1-（4-吗啉苯基）-2-吗啉基-1-丙酮的制备方法

  摘要：

  本发明提供了一种2‑甲基‑1‑(4‑吗啉苯基)‑2‑吗啉基‑1‑丙酮的制备方法，所述制备方法以2‑甲基‑1‑(4‑氟苯基)‑2‑吗啉基‑1‑丙酮为原料，以吗啉为溶剂，水为催化剂，进行吗啉取代苯环上氟原子的反应，副反应少，杂质含量少，后处理简单；相较于采用二甲基亚砜为溶剂，碳酸钾为催化剂的合成体系，本发明上述制备方法的反应体系的组成更加简单，且过量的吗啉和作为催化剂的水后续可通过共沸去除，工艺成本低。

  公开号：

  CN114315759B

文献信息

• Photopolymerizable compositions containing aminoaryl ketone
  申请人：Ciba-Geigy Corporation

  公开号：US05145885A1

  公开（公告）日：1992-09-08

  The photopolymerizable composition described contains A) at least one ethylenically unsaturated photopolymerizable compound, B) a photoinitiator of the formula I ##STR1## and C) a photosensitizer from the group of aromatic carbonyl compounds having a triplet energy of 225-310 kJ/mol, for example xanthones, thioxanthones, coumarins, phthalimides, phenones and the like. Ar is phenyl substituted in the 4-position by a substituted amino group, R.sup.1 and R.sup.2 are alkyl, R.sup.3 and R.sup.4 are alkyl or alkoxyalkyl, or R.sup.3 and R.sup.4 together are 3-oxapentamethylene. Said sensitizers C) raise the activity of said photoinitiators (B) without shortening the shelf life of the mixtures. The photocurable mixtures are used especially as binders for printing inks or paints.

  所述的光聚合物组合物包含A）至少一种乙烯基不饱和的光聚合物化合物，B）式I的光引发剂##STR1##和C）来自具有三重态能量为225-310 kJ/mol的芳香族羰基化合物组的光敏剂，例如黄酮，噻黄酮，香豆素，邻苯二甲酰亚胺，苯酮等。其中Ar是苯基在4位上被取代的氨基基团，R1和R2是烷基，R3和R4是烷基或烷氧基烷基，或R3和R4一起是3-氧代戊烷亚甲基。所述的敏化剂C）提高了所述光引发剂（B）的活性，而不缩短混合物的货架寿命。这种光固化混合物特别用作印刷油墨或涂料的粘合剂。
• Aminoaryl ketone photoinitiators
  申请人：Ciba-Geigy Corporation

  公开号：US04992547A1

  公开（公告）日：1991-02-12

  The photopolymerizable mixture described contains (A) at least one ethylenically unsaturated photopolymerisable compound, (B) a photoinitiator of the formula I ##STR1## and (C) a photosensitiser from the group of aromatic carbonyl compounds having a triplet energy of 225-310 kJ/mol, for example xanthones, thioxianthones, coumarins, phthalimides, phenones and the like. Ar is phenyl substituted in the 4-position by a substituted amino group, R.sup.1 and R.sup.2 are alkyl, R.sup.3 and R.sup.4 are alkyl or alkoxyalkyl, or R.sup.3 and R.sup.4 together are 3-oxapentamethylene. Said sensitisers (C) raise the activity of said photoinitiators (B) without shortening the shelf life of the mixtures. The photocurable mixtures are used especially as binders for printing inks or paints.

  所述光敏混合物包含（A）至少一种乙烯基不饱和光敏聚合物化合物，（B）式I的光引发剂##STR1##和（C）从芳香族羰基化合物组中具有225-310 kJ / mol的三重态能量的光敏剂，例如黄酮，噻黄酮，香豆素，邻酰胺，苯酮等。其中Ar是在4位被取代氨基基团取代的苯基，R1和R2是烷基，R3和R4是烷基或烷氧基烷基，或R3和R4一起是3-氧代戊亚甲基。所述感光剂（C）提高了所述光引发剂（B）的活性，而不缩短混合物的货架寿命。该光固化混合物特别用作印刷油墨或涂料的粘合剂。
• US4992547A
  申请人：——

  公开号：US4992547A

  公开（公告）日：1991-02-12
• US5145885A
  申请人：——

  公开号：US5145885A

  公开（公告）日：1992-09-08
• EPR studies on the photofragmentation of 2,2-dialkyl-2-alkylaminoacetophenones
  作者：Detlev Leopold、Hanns Fischer

  DOI：10.1039/p29920000513

  日期：——

  Free radical reactions induced by photolysis of 2,2-dialkyl-2-alkylaminoacetophenone photocuring agents have been studied by continuous wave (CW) and time-resolved EPR spectroscopy. In all solvents alpha-cleavage from the triplet state is the major process. In hydrogen donor solvents it is accompanied by photoreduction followed by a rapid amine elimination from the ketyl radical intermediate. The benzoyl and alpha-aminoalkyl radicals resulting from alpha-cleavage readily add to acrylonitrile whereas radicals formed by photoreduction do not.