(2R,3S,4S,5S)-2-(hydroxymethyl)-6-propan-2-yloxyoxane-3,4,5-triol | 1013635-67-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2R,3S,4S,5S)-2-(hydroxymethyl)-6-propan-2-yloxyoxane-3,4,5-triol
• CAS: 1013635-67-0
• 化学式: C₉H₁₈O₆
• 分子量: 222.238
• InChiKey: UOEFDXYUEPHESS-PPRREVKSSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.4
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  99.4
• 氢给体数：
  4
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  (2R,3S,4S,5S)-2-(hydroxymethyl)-6-propan-2-yloxyoxane-3,4,5-triol 、 乙酸酐 反应 2.0h， 生成 iso-propyl 2,3,4,6-tetra-O-acetyl-β-D-mannopyranoside 、 isopropyl 2,3,4,6-tetrakis-O-acetyl-α-D-mannopyranoside
  参考文献：
  名称：

  Efficient glycosylation of unprotected sugars using sulfamic acid: A mild eco-friendly catalyst

  摘要：

  Sulfamic acid, a mild and environmentally benign catalyst has been successfully used in the Fischer glycosylation of unprotected sugars for the preparation alkyl glycosides. A diverse range of aliphatic alcohols have been used to prepare a series of alkyl glycosides in good to excellent yield. (C) 2011 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.catcom.2011.07.016

文献信息

• ENZYME-DIRECTED IMMUNOSTIMULANT AND USES THEREOF CROSS-REFERENCE TO RELATED APPLICATION(S)
  申请人：Washington State University

  公开号：US20180094015A1

  公开（公告）日：2018-04-05

  The disclosed invention relates to the novel composition of matter that allows for the controlled release of highly active compounds to be delivered to a desired site. This novel composition utilizes the immune system to allow for the controlled release of desired compounds. The present invention can utilize a plurality of highly active compounds, with one embodiment being the use of chemotherapeutics for the treatment of cancer.

  所披露的发明涉及一种新型物质组合，该组合允许高活性化合物的受控释放以传递到所需的部位。这种新型组合利用免疫系统，以实现所需化合物的受控释放。本发明可以利用多种高活性化合物，其中一种实施方式是使用化疗药物治疗癌症。