1-(6-chloropyridin-3-yl)-2,2-dimethylpropanone | 139042-66-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-(6-chloropyridin-3-yl)-2,2-dimethylpropanone
• 英文别名: 1-(6-Chloropyridin-3-yl)-2,2-dimethylpropan-1-one
• CAS: 139042-66-3
• 化学式: C₁₀H₁₂ClNO
• 分子量: 197.664
• InChiKey: WJUZLSGVHZACKB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  30
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2,5-二溴吡啶 在 正丁基锂 、 三氟化硼乙醚 、 (-)-diisopinocamphenylborane chloride 作用下， 反应 25.5h， 生成 1-(6-chloropyridin-3-yl)-2,2-dimethylpropanone
  参考文献：
  名称：

  Bolm, Carsten; Ewald, Martina; Felder, Marcel, Chemische Berichte, 1992, vol. 125, # 5, p. 1169 - 1190

  摘要：

  DOI：

文献信息

• PYRAZOLE AMIDE COMPOUNDS AND USES THEREOF
  申请人：Liu Changling

  公开号：US20130225585A1

  公开（公告）日：2013-08-29

  Disclosed is a pyrazole amide compound having fungicidal activity, with a structure shown by the general formula (I): Each of the substituents of the compound being defined as in the description. The compound of the present invention has fungicidal activity, and excellent prevention and controlling effects on diseases, such as cucumber downy mildew, corn rust, wheat powdery mildew, rice blast, etc., and in particular, a better prevention and controlling effect on cucumber downy mildew and corn rust. Also disclosed is a process for preparing the compound, a fungicidal composition containing the compound of general formula (I) and the use thereof in preventing and controlling disease in crops.

  本发明揭示了一种具有杀真菌活性的吡唑酰胺化合物，其结构由通式（I）所示：化合物的每个取代基均如描述中所定义。本发明的化合物具有杀真菌活性，并对瓜类霜霉病、玉米锈病、小麦白粉病、水稻稻瘟等疾病具有优异的预防和控制效果，尤其对瓜类霜霉病和玉米锈病有更好的预防和控制效果。还公开了一种制备该化合物的方法，含有通式（I）化合物的杀真菌组合物以及其在农作物疾病预防和控制中的应用。
• PYRAZOLYL PYRIMIDINAMINE COMPOUND AND APPLICATION THEREOF
  申请人：SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD.

  公开号：US20160332991A1

  公开（公告）日：2016-11-17

  Disclosed are pyrazolyl pyrimidinamine compounds with structures as shown in Formula I: The definitions of each of the substituents can be seen in the description. The compounds of present invention have a broad spectrum of bactericidal, insecticidal and acaricidal activity, and have good control effect on downy mildew of cucumber, powdery mildew of wheat, corn rust, anthracnosis of cucumber and the like, and especially have better control effect on downy mildew of cucumber, powdery mildew of wheat and anthracnosis of cucumber. The compounds of present invention also show good insecticidal activity, part of the compounds, at very low doses, have excellent control effect on diseases caused by Plutella xylostella , armyworm, Myzus persicae, Tetranychus cinnabarinus etc.

  本发明揭示了具有如下式所示结构的吡唑基嘧啶胺化合物：每个取代基的定义可在说明书中看到。本发明的化合物具有广谱的杀菌、杀虫和杀螨活性，并且对黄瓜霜霉病、小麦白粉病、玉米锈病、黄瓜炭疽病等病害具有良好的控制效果，特别对黄瓜霜霉病、小麦白粉病和黄瓜炭疽病有更好的控制效果。本发明的化合物还表现出良好的杀虫活性，其中部分化合物在非常低剂量下对由小菜蛾、军虫、桃蚜、细毛螨等引起的疾病具有出色的控制效果。
• SUBSTITUTED PYRIMIDINE COMPOUND AND PREPARATION METHOD AND USE THEREOF
  申请人：SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD.

  公开号：US20210015100A1

  公开（公告）日：2021-01-21

  The present invention discloses a substituted pyrimidine compound. The structure is shown in general formula I. The definition of each substituent in the formula is described in the description. The compound of the present invention has broad-spectrum fungicidal, insecticidal and acaricidal activity, and has excellent control effects on cucumber downy mildew, powdery mildew, corn rust, anthrax, rice blast, aphids, Tetranychus cinnabarinus and the like.

  本发明公开了一种取代嘧啶化合物。其结构如一般式I所示。公式中每个取代基的定义在描述中有所描述。本发明的化合物具有广谱杀真菌、杀虫和杀螨活性，并对黄瓜霜霉病、白粉病、玉米锈病、炭疽病、稻瘟病、蚜虫、红蜘蛛等具有优异的防治效果。
• Substituted Pyrazole Compounds Containing Pyrimidine and Preparation Method and Use Thereof
  申请人：Shenyang Sinochem Agrochemicals R&D Co., Ltd.

  公开号：US20180141961A1

  公开（公告）日：2018-05-24

  Disclosed are substituted pyrazole compounds containing pyrimidinyl as shown in Formula I: The definitions of each of the substituents can be seen in the description. The compounds of present invention have a good spectrum of bactericidal, insecticidal and acaricidal activity,and have good control effect on downy mildew of cucumber, powdery mildew of wheat, corn rust, rice blast, cucumber anthracnosis and the like. The compounds of present invention also show good insecticidal activity.

  本公开的是含有嘧啶基团的取代吡唑化合物，其化学式如下所示：各个取代基的定义可在说明中看到。本发明的化合物具有良好的杀菌、杀虫和杀螨活性，并对黄瓜霜霉病、小麦白粉病、玉米锈病、稻瘟病、黄瓜炭疽病等具有良好的防治效果。本发明的化合物还表现出良好的杀虫活性。
• Substituted pyrazole compounds containing pyrimidine and preparation method and use thereof
  申请人：Shenyang Sinochem Agrochemicals R&D Co., Ltd.

  公开号：US11008339B2

  公开（公告）日：2021-05-18

  Disclosed are substituted pyrazole compounds containing pyrimidinyl as shown in Formula I: The definitions of each of the substituents can be seen in the description. The compounds of present invention have a good spectrum of bactericidal, insecticidal and acaricidal activity, and have good control effect on downy mildew of cucumber, powdery mildew of wheat, corn rust, rice blast, cucumber anthracnosis and the like. The compounds of present invention also show good insecticidal activity.

  所公开的是含有如式 I 所示嘧啶基的取代吡唑化合物： 各取代基的定义见说明。本发明化合物具有良好的杀菌、杀虫和杀螨活性谱，对黄瓜霜霉病、小麦白粉病、玉米锈病、稻瘟病、黄瓜炭疽病等具有良好的防治效果。本发明的化合物还具有良好的杀虫活性。