(S)-2-((4S,5R,6R)-6-{(2R,5R,2'S,5'R)-5'-[(S)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2,5'-dimethyl-octahydro-[2,2']bifuranyl-5-ylmethyl}-2,2,5-trimethyl-[1,3]dioxan-4-yl)-propan-1-ol | 173241-16-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (S)-2-((4S,5R,6R)-6-{(2R,5R,2'S,5'R)-5'-[(S)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2,5'-dimethyl-octahydro-[2,2']bifuranyl-5-ylmethyl}-2,2,5-trimethyl-[1,3]dioxan-4-yl)-propan-1-ol
• 英文别名: (2S)-2-[(4S,5R,6R)-6-[[(2R,5R)-5-[(2S,5R)-5-[(1S)-1-[tert-butyl(dimethyl)silyl]oxyethyl]-5-methyloxolan-2-yl]-5-methyloxolan-2-yl]methyl]-2,2,5-trimethyl-1,3-dioxan-4-yl]propan-1-ol
• CAS: 173241-16-2
• 化学式: C₂₉H₅₆O₆Si
• 分子量: 528.846
• InChiKey: XVSZRTQUYDALOZ-GBVKWFAZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.45
• 重原子数：
  36
• 可旋转键数：
  9
• 环数：
  3.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  66.4
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  三甲基乙酰氯 、 (S)-2-((4S,5R,6R)-6-{(2R,5R,2'S,5'R)-5'-[(S)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2,5'-dimethyl-octahydro-[2,2']bifuranyl-5-ylmethyl}-2,2,5-trimethyl-[1,3]dioxan-4-yl)-propan-1-ol 在 4-二甲氨基吡啶 作用下， 生成 2,2-Dimethyl-propionic acid (2S,3S,4R,5R)-3,5-dihydroxy-6-[(5R,5'R)-5'-((S)-1-hydroxy-ethyl)-2,5'-dimethyl-octahydro-[2,2']bifuranyl-5-yl]-2,4-dimethyl-hexyl ester
  参考文献：
  名称：

  Cascade Cyclizations of Cyclic Sulfates: An Enantioselective Alternative to Polyepoxide Cyclizations in the Synthesis of Poly(tetrahydrofurans)

  摘要：

  DOI：

  10.1021/ja00156a031
• 作为产物：
  描述：

  2,2-Dimethyl-propionic acid (S)-2-((4S,5R,6R)-6-{(2R,5R,2'S,5'R)-5'-[(S)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-2,5'-dimethyl-octahydro-[2,2']bifuranyl-5-ylmethyl}-2,2,5-trimethyl-[1,3]dioxan-4-yl)-propyl ester 在 二异丁基氢化铝 作用下， 生成 (S)-2-((4S,5R,6R)-6-{(2R,5R,2'S,5'R)-5'-[(S)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2,5'-dimethyl-octahydro-[2,2']bifuranyl-5-ylmethyl}-2,2,5-trimethyl-[1,3]dioxan-4-yl)-propan-1-ol
  参考文献：
  名称：

  Cascade Cyclizations of Cyclic Sulfates: An Enantioselective Alternative to Polyepoxide Cyclizations in the Synthesis of Poly(tetrahydrofurans)

  摘要：

  DOI：

  10.1021/ja00156a031