4-乙酰氧基-N,N-二异丙基色胺 | 936015-60-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 中文名称: 4-乙酰氧基-N,N-二异丙基色胺
• 英文名称: 4-acetoxy-3-(N,N-diisopropylaminoethyl)indole
• 英文别名: 4-Acetoxy-N,N-diisopropyltryptamine；[3-[2-[di(propan-2-yl)amino]ethyl]-1H-indol-4-yl] acetate
• CAS: 936015-60-0
• 化学式: C₁₈H₂₆N₂O₂
• 分子量: 302.417
• InChiKey: ZPAOVGZYDSXCPK-UHFFFAOYSA-N

物化性质

• 沸点：
  442.8±35.0 °C(Predicted)
• 密度：
  1.082±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  22
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  45.3
• 氢给体数：
  1
• 氢受体数：
  3

安全信息

• 海关编码：
  2933990090

反应信息

• 作为反应物：
  描述：

  4-乙酰氧基-N,N-二异丙基色胺 在 水 作用下， 生成 4-羟基-N,N-二异丙基色胺
  参考文献：
  名称：

  WO2023/108260

  摘要：

  公开号：
• 作为产物：
  描述：

  4-乙酰氧基吲哚 在 草酰氯 、 lithium aluminium tetrahydride 作用下， 以 甲基叔丁基醚 、 四氢呋喃 为溶剂， 生成 4-乙酰氧基-N,N-二异丙基色胺
  参考文献：
  名称：

  TRYPTAMINE PRODRUGS

  摘要：

  本发明提供了一种色胺前药化合物。化合物由公式(I)表示，其中每个符号如说明书中所述，或其盐或离子，被转化为具有5HT2A受体激动剂活性的活性物质，并用作抗抑郁剂的药物。

  公开号：

  US20210403425A1

文献信息

• PESTICIDAL COMPOSITION COMPRISING INDOLE DERIVATES
  申请人：Bednarek Pawel

  公开号：US20090028796A1

  公开（公告）日：2009-01-29

  The present invention is directed to pesticidal compositions comprising indole derivatives. These indole derivatives are especially active against phytopathogenic fungi. Furthermore, the invention relates to the use of indole derivatives for the production of pesticides and the use of the compositions according to the invention as pesticides. The present invention is also directed to a process for producing a pesticidal composition and to pesticidal compositions prepared by this process. In addition, the invention relates to a process for preventing or combating pests and to a process for protecting plants against pests, especially against phytopathogenic fungi. Further, the invention is directed to plants or seeds as well as objects or materials which have been protected against pests by treatment with a composition according to the invention. Further, the invention is directed to a method for identifying a substance having pesticidal activity. Further, the invention is directed to a method of identifying the mode of action of and/or of providing binding proteins for a pesticidal compound of the present invention. Finally, the invention is directed to a method for diagnosing pest infection of a plant and to the use of a pesticidal compound of the present invention as diagnostic markers.

  本发明涉及包含吲哚衍生物的杀虫组合物。这些吲哚衍生物特别对植物病原真菌具有活性。此外，本发明涉及使用吲哚衍生物制备杀虫剂以及使用本发明中的组合物作为杀虫剂。本发明还涉及制备杀虫组合物的过程以及通过该过程制备的杀虫组合物。此外，本发明还涉及预防或对抗害虫的过程以及保护植物免受害虫，特别是植物病原真菌的过程。此外，本发明还涉及经过本发明中的组合物处理后受到保护的植物或种子以及物体或材料。本发明还涉及识别具有杀虫活性的物质的方法。此外，本发明还涉及识别本发明中杀虫化合物的作用方式和/或提供结合蛋白的方法。最后，本发明涉及诊断植物害虫感染的方法以及使用本发明中的杀虫化合物作为诊断标记的方法。
• [EN] COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS<br/>[FR] FORMULATIONS SALINES DE COMPOSÉS PHARMACEUTIQUES À BASE D'AGENTS COMPLEXANTS
  申请人：BEXSON BIOMEDICAL INC

  公开号：WO2022109050A1

  公开（公告）日：2022-05-27

  Provided herein are pharmaceutical formulations and pharmaceutical compound salts which utilize complexing agents as counterions. Such formulations and salts are useful for treating a variety of disease and disorders.

  本文提供了药物制剂和药物化合物盐，其使用络合剂作为反离子。这些制剂和盐对治疗各种疾病和障碍有用。
• [EN] MODIFIED INDOLE ALKALOIDS FOR THERAPEUTIC USES<br/>[FR] ALCALOÏDES INDOLIQUES MODIFIÉS POUR UTILISATIONS THÉRAPEUTIQUES
  申请人：NEW ATLAS BIOTECHNOLOGIES INC

  公开号：WO2022133314A1

  公开（公告）日：2022-06-23

  Disclosed herein are enzymatic and modified host cell methods for prepared modified indole alkaloids. Also disclosed herein are modified indole alkaloids and their therapeutic use for treating diseases and disorders.

  本文披露了制备改性吲哚生物碱的酶和改性宿主细胞方法。本文还披露了改性吲哚生物碱及其治疗用于治疗疾病和疾病的方法。
• Methods of treating food allergy conditions
  申请人：Palo Alto Investors LP

  公开号：US11045454B2

  公开（公告）日：2021-06-29

  Methods for treating a subject for a food allergy condition are provided. Aspects of the methods include administering to a subject in need thereof a psychedelic agent in a manner effective to treat the subject for a food allergy condition. Effective administration of a psychedelic agent may include administering the psychedelic agent in an amount effective to treat the subject for the food allergy condition. In some instances, the subject is known to have a food allergy condition.

  本文提供了治疗食物过敏症的方法。这些方法的各个方面包括以有效治疗食物过敏症的方式向有需要的受试者施用迷幻剂。有效施用迷幻剂可包括以有效治疗受试者食物过敏症的量施用迷幻剂。在某些情况下，受试者已知患有食物过敏症。
• Biosynthetic cannabinoid production methods
  申请人：INSECTERGY, LLC

  公开号：US11180781B2

  公开（公告）日：2021-11-23

  The present disclosure relates to the field of commercial scale production and processing of biosynthetic cannabinoids produced by growing genetically modified microalgae in a photo-bioreactor to a produce biosynthetic cannabinoids, separating a liquid nutrient medium from the genetically modified microalgae, and extracting the biosynthetic cannabinoids to produce an extracted biosynthetic cannabinoid, then distilling the extracted biosynthetic cannabinoid to produce the biosynthetic cannabinoid distillate. Biosynthetic cannabinoid distillates may be used foodstuffs, beverages, nanoemulsions, spray-dried water-soluble powders, cosmetics, or topicals.

  本公开涉及生物合成大麻素的商业规模生产和加工领域，其方法是在光生物反应器中培养转基因微藻以产生生物合成大麻素，从转基因微藻中分离液体营养介质，提取生物合成大麻素以产生提取生物合成大麻素，然后蒸馏提取生物合成大麻素以产生生物合成大麻素蒸馏物。生物合成大麻素蒸馏物可用于食品、饮料、纳米乳剂、喷雾干燥水溶性粉末、化妆品或外用药。