(4-(tetradecyloxy)piperidine-2,6-diyl)dimethanol | 1393660-74-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (4-(tetradecyloxy)piperidine-2,6-diyl)dimethanol
• 英文别名: [6-(Hydroxymethyl)-4-tetradecoxypyridin-2-yl]methanol；[6-(hydroxymethyl)-4-tetradecoxypyridin-2-yl]methanol
• CAS: 1393660-74-6
• 化学式: C₂₁H₃₇NO₃
• 分子量: 351.53
• InChiKey: FMDUDQFNMRPQKZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.8
• 重原子数：
  25
• 可旋转键数：
  16
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.76
• 拓扑面积：
  62.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  (4-(tetradecyloxy)piperidine-2,6-diyl)dimethanol 在 selenium(IV) oxide 、 dibenzylammonium hexafluorophosphate 作用下， 以 1,4-二氧六环 、 乙腈 为溶剂， 反应 16.0h， 生成 33-Tetradecoxy-10,13,16,19,22-pentaoxa-3,29,35-triazatetracyclo[29.3.1.04,9.023,28]pentatriaconta-1(34),2,4,6,8,23,25,27,29,31(35),32-undecaene
  参考文献：
  名称：

  Synthesis of [2]Catenanes by Template-Directed Clipping Approach

  摘要：

  A series of [2]catenanes were efficiently synthesized in high yields by a template-directed clipping approach with the formation of one macrocycle around another macrocycle containing a dialkylammonium recognition site. Their structures were identified by the NMR spectra and ESI mass spectrometry, and their geometries were investigated by the theoretical calculation.

  DOI：

  10.1021/jo3012804
• 作为产物：
  描述：

  dimethyl 4-hydroxypyridine-2,6-dicarboxylate 在 sodium tetrahydroborate 作用下， 以 四氢呋喃 、 甲醇 为溶剂， 反应 24.0h， 以83%的产率得到(4-(tetradecyloxy)piperidine-2,6-diyl)dimethanol
  参考文献：
  名称：

  Synthesis of [2]Catenanes by Template-Directed Clipping Approach

  摘要：

  A series of [2]catenanes were efficiently synthesized in high yields by a template-directed clipping approach with the formation of one macrocycle around another macrocycle containing a dialkylammonium recognition site. Their structures were identified by the NMR spectra and ESI mass spectrometry, and their geometries were investigated by the theoretical calculation.

  DOI：

  10.1021/jo3012804

文献信息

• Synthesis of [2]Catenanes by Template-Directed Clipping Approach
  作者：Ziyong Li、Wenju Liu、Jishan Wu、Sheng Hua Liu、Jun Yin

  DOI：10.1021/jo3012804

  日期：2012.8.17

  A series of [2]catenanes were efficiently synthesized in high yields by a template-directed clipping approach with the formation of one macrocycle around another macrocycle containing a dialkylammonium recognition site. Their structures were identified by the NMR spectra and ESI mass spectrometry, and their geometries were investigated by the theoretical calculation.