1-(6-methoxypyridin-3-yl)cyclopropanecarboxylic acid | 1060807-02-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-(6-methoxypyridin-3-yl)cyclopropanecarboxylic acid
• 英文别名: 1-(6-methoxypyridin-3-yl)cyclopropane-1-carboxylic acid
• CAS: 1060807-02-4
• 化学式: C₁₀H₁₁NO₃
• 分子量: 193.202
• InChiKey: CASNAIUVQSOWSE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  59.4
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1-(6-methoxypyridin-3-yl)cyclopropanecarboxylic acid 、 在 4-二甲氨基吡啶 1,2-二氯乙烷 作用下， 以 二氯甲烷 为溶剂， 反应 4.0h， 生成
  参考文献：
  名称：

  Substituted benzimidazole derivatives as melanocortin 4 receptor antagonists

  摘要：

  本发明涉及取代苯并咪唑衍生物作为黑色素皮质素-4受体（MC-4R）调节剂。

  公开号：

  EP2439197A1

文献信息

• [EN] USE OF SUBSTITUTED DITHIINE-TETRACARBOXIMIDES FOR COMBATING PHYTOPATHOGENIC FUNGI<br/>[FR] UTILISATION DE DITHIINE-TÉTRACARBOXIMIDES SUBSTITUÉS POUR COMBATTRE DES CHAMPIGNONS PHYTOPATHOGÈNES
  申请人：BASF SE

  公开号：WO2012139987A1

  公开（公告）日：2012-10-18

  The present invention relates to the use of dithiine-tetracarboximide compounds of formula I as defined in the description, and the N-oxides, and salts thereof for combating harmful fungi and seed coated with at least one such compound. The invention also relates to novel dithiine-tetracarboximides, processes and intermediates for preparing these compounds and also to compositions comprising at least one such compound.

  本发明涉及使用如描述中定义的式I的二硫代四羧酰亚胺化合物，以及其N-氧化物和盐来对抗有害真菌，并且至少包含一种这样化合物的种子包衣。该发明还涉及新颖的二硫代四羧酰亚胺化合物，用于制备这些化合物的过程和中间体，以及包含至少一种这样化合物的组合物。
• SUBSTITUTED AMIDE COMPOUND
  申请人：Kawaminami Eiji

  公开号：US20120184521A1

  公开（公告）日：2012-07-19

  A substituted amide compound is useful as an active ingredient of a pharmaceutical composition, in particular a pharmaceutical composition for treating diseases caused by lysophosphatidic acid (LPA). The compound is of a formula: In this formula, A is an optionally substituted aryl, etc.; B is an optionally substituted 5-membered aromatic hetero ring group; X is a single bond or —(CR X1 R X2 ) n —; n is 1, 2, 3, or 4; R X1 and R X2 are hydrogen, etc.; Y 1 to Y 5 are each CR Y or N; each R Y is hydrogen, etc.; R 1 and R 2 are hydrogen, etc.; m is 1, 2, or 3; R 3 is hydrogen, etc.; and R 4 is an optionally substituted lower alkyl, etc.

  一种替代酰胺化合物作为药物组合物的活性成分是有用的，特别是用于治疗由溶血磷脂酸（LPA）引起的疾病的药物组合物。该化合物的化学式如下： 在这个化学式中，A是可选地取代的芳基等；B是可选地取代的5-成员芳香杂环基团；X是单键或—(CR X1 R X2 ) n —；n为1、2、3或4；R X1 和R X2 为氢等；Y 1 到Y 5 分别为CR Y 或N；每个R Y 为氢等；R 1 和R 2 为氢等；m为1、2或3；R 3 为氢等；R 4 为可选地取代的低碳烷基等。
• [EN] PESTICIDE COMPOUNDS<br/>[FR] COMPOSÉS PESTICIDES
  申请人：BASF SE

  公开号：WO2015007682A1

  公开（公告）日：2015-01-22

  The present invention relates to novel compounds of the formula I and the N-oxides, stereoisomers, tautomers and agriculturally or veterinarily acceptable salts thereof wherein C1 is C or CH; C2 is C or CH; A1 is N or C; A2 is N, C(R2), N(R3), O, S or C(R4,R5); and A3 is N, O, S, N(R6), C(R7) or C(R8,R9); where one or two non-adjacent bonds in the 5-membered ring formed by C1, C2, A1, A2 and A3 are double bonds, while the others are single bonds, provided that the bond between A1 and A2 or the bond between A1 and C1 or the bond between A2 and A3 or the bond between C1 and C2 or the bond between A3 and C2 is a double bond further provided that at least one of A1, A2 and A3 is N, N(R3) or N(R6), and where Ar, R1, R2, R3, R4,R5, R6, R7, R8, R9 and (R)k are as defined in the claims and in the description, which are useful for combating or controlling invertebrate pests, in particular arthropod pests and nematodes. The invention also relates to a method for controlling invertebrate pests by using these compounds and to plant propagation material and to an agricultural and a veterinary composition comprising said compounds.

  本发明涉及公式I的新化合物及其N-氧化物、立体异构体、互变异构体和农业或兽医可接受的盐，其中C1为C或CH；C2为C或CH；A1为N或C；A2为N、C(R2)、N(R3)、O、S或C(R4,R5)；A3为N、O、S、N(R6)、C(R7)或C(R8,R9)；其中由C1、C2、A1、A2和A3形成的5元环中的一个或两个非相邻键为双键，而其他键为单键，前提是A1和A2之间的键或A1和C1之间的键或A2和A3之间的键或C1和C2之间的键或A3和C2之间的键为双键，进一步前提是A1、A2和A3中至少有一个为N、N(R3)或N(R6)，其中Ar、R1、R2、R3、R4、R5、R6、R7、R8、R9和(R)k的定义如权利要求和说明书中所述，用于对抗或控制无脊椎动物害虫，特别是节肢动物害虫和线虫。该发明还涉及一种利用这些化合物控制无脊椎动物害虫的方法，以及包括所述化合物的植物繁殖材料和农业和兽医组合物。
• [EN] FUNGICIDAL SUBSTITUTED 1-{2-[2-HALO-4-(4-HALOGEN-PHENOXY)-PHENYL]-2-ALKOXY-2-ALKYNYL/ALKENYL-ETHYL}-1H-[1,2,4]TRIAZOLE COMPOUNDS<br/>[FR] COMPOSÉS FONGICIDES SUBSTITUÉS DE 1-{2-[2-HALO-4-(4-HALOGÈNE-PHÉNOXY)-PHÉNYL]-2-ALCOXY-2-ALKYNYLE/ALCÉNYLE-ÉTHYL}-1H-[1,2,4]TRIAZOLE
  申请人：BASF SE

  公开号：WO2013024083A1

  公开（公告）日：2013-02-21

  The present invention relates to substituted 1-2-[2-halo-4-(4-halogen-phenoxy)-phenyl]-2-alkoxy-2-alkynyl-ethyl}-1H-[1,2,4]triazole compounds of formula (I) as defined in the description, and the N-oxides, and salts thereof, processes and intermediates for preparing these compounds and also to compositions comprising at least one such compound. The invention also relates to the use of such compounds and compositions for combating harmful fungi and seed coated with at least one such compound.

  本发明涉及换位的1-2-[2-卤代-4-(4-卤代苯氧基)苯基]-2-烷氧基-2-烷炔基乙基}-1H-[1,2,4]三唑化合物，其化学式为(I)中所定义的化合物，以及其N-氧化物和盐，用于制备这些化合物的过程和中间体，以及包含至少一种此类化合物的组合物。该发明还涉及这些化合物和组合物用于对抗有害真菌以及至少包含一种此类化合物的种子包衣的用途。
• [EN] ISOTHIAZOLINE COMPOUNDS FOR COMBATING INVERTEBRATE PESTS<br/>[FR] COMPOSÉS ISOTHIAZOLINES POUR COMBATTRE LES ORGANISMES NUISIBLES INVERTÉBRÉS
  申请人：BASF SE

  公开号：WO2013092943A1

  公开（公告）日：2013-06-27

  The present invention relates to isothiazoline compounds of formula (I) wherein the variables are as defined in the claims or the description, which are useful for combating or controlling invertebrate pests, in particular arthropod pests and nematodes, and to a method for producing them. The invention also relates to a method for controlling invertebrate pests by using these compounds and to plant propagation material and to an agricultural and a veterinary composition comprising said compounds.

  本发明涉及公式（I）中变量如索赔或描述中定义的异噻唑啉化合物，这些化合物对抗或控制无脊椎动物害虫，特别是节肢动物害虫和线虫有用，并提供了一种生产它们的方法。该发明还涉及使用这些化合物控制无脊椎动物害虫的方法，以及包含该化合物的植物繁殖材料、农业和兽医组合物。