1-Methyl-3-phenacyl-3,4-dihydroquinoxalin-2-one

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-Methyl-3-phenacyl-3,4-dihydroquinoxalin-2-one
• 化学式: C₁₇H₁₆N₂O₂
• 分子量: 280.32
• InChiKey: IBBGIJOLHVUMHC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  21
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  49.4
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  苯乙酮 、 1-methyl-2(1H)-quinoxalinone 在 tetrafluoroboric acid 、 copper(II) tetrafluroborate hexahydrate 作用下， 以 1,2-二氯乙烷 为溶剂， 生成 1-Methyl-3-phenacyl-3,4-dihydroquinoxalin-2-one
  参考文献：
  名称：

  Feasible Synthesis of N,O‐Bidentate Difluoroboron Chromophores through Direct Functionalization of Quinoxalin‐2(1H)‐ones with Ketones in One Shot

  摘要：

  Organic difluoroboron complexes are a kind of potential platforms for a wide range of applications owing to their excellent photophysical properties. Herein, we have explored a simple and direct synthesis methodology for a library of N,O‐bidentate difluoroboron complexes from quinoxalin‐2(1H)‐ones and ketones in one shot. The photophysical properties of the generated complexes were evaluated and the application potential of these compounds on subcellular imaging was also explored.

  DOI：

  10.1002/cjoc.202300656