quinolin-8-yl 2-phenylacetate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: quinolin-8-yl 2-phenylacetate
• 化学式: C₁₇H₁₃NO₂
• 分子量: 263.296
• InChiKey: MMXRXAZZADZZOD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  20
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  39.2
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  8-羟基喹啉 在 chloro[(4,5-bis(diphenylphosphino)-9,9-dimethylxanthene)-2-(2’-amino-1,1’-biphenyl)]palladium(II) 、 三乙胺 作用下， 以 甲苯 为溶剂， 反应 3.33h， 生成 quinolin-8-yl 2-phenylacetate
  参考文献：
  名称：

  喹啉-8-基甲酸酯：微波反应器中小规模羰基化反应的新选择

  摘要：

  描述了在微波反应器中通过使用甲酸喹啉-8-基酯进行芳基或苄基卤的小规模羰基化的方便程序。所得的 8-酰氧基喹啉在酰基转移反应中比苯基酯更具反应性，并且证明了它们在酯和酰胺生产中的效用。

  DOI：

  10.1055/s-0040-1707187

文献信息

• Palladium-Catalyzed Aryl C–H Olefination with Unactivated, Aliphatic Alkenes
  作者：Arghya Deb、Sukdev Bag、Rajesh Kancherla、Debabrata Maiti

  DOI：10.1021/ja5082734

  日期：2014.10.1

  of unactivated aliphatic olefins, has discouraged the use of this greener alternative. Overcoming this serious limitation, we report here a palladium-catalyzed chelation-assisted ortho C-H bond olefination of phenylacetic acid derivatives with unactivated, aliphatic alkenes in good to excellent yields with high regio- and stereoselectivities. The versatility of this operationally simple method has

  芳基卤化物和烯烃之间的钯催化偶联（Mizoroki-Heck 反应）是合成复杂有机分子最流行的反应之一。芳基卤化物前体（或它们的等价物）的可用性有限、合成有问题和成本较高，这鼓励了对芳基碳氢 (CH) 键的直接烯化（Fujiwara-Moritani 反应）的探索。尽管取得了重大进展，但受限制的底物范围，尤其是未活化脂肪族烯烃的不合规性，阻碍了这种更环保的替代品的使用。克服了这一严重的局限性，我们在此报告了一种钯催化螯合辅助的邻 CH 键烯化苯乙酸衍生物与未活化的脂肪族烯烃，产率高，区域选择性和立体选择性高。
• HARD COAT LAMINATED FILM
  申请人：Riken Technos Corporation

  公开号：EP3272529A1

  公开（公告）日：2018-01-24

  A hard coat laminated film according to an embodiment of the present invention has, from the surface layer side, a first hard coat and a transparent resin film layer. The first hard coat is formed from a coating material comprising: (A) 100 parts by mass of a polyfunctional (meth)acrylate; and (B) 1-100 parts by mass of an N-substituted (meth)acrylamide compound. The transparent resin film has a first hard coat forming surface which is a poly(meth)acrylic imide resin. A hard coat laminated film according to another embodiment of the present invention has, from the surface layer side, a second hard coat, the first hard coat and the transparent resin film layer. The second hard coat is formed from a coating material which comprises: (A) 100 parts by mass of a polyfunctional (meth)acrylate; (E) 0.01-7 parts by mass of a water repelling agent; and (F) 0.01-10 parts by mass of a silane coupling agent; without inorganic particles.

  根据本发明一个实施例的硬涂层层压薄膜，从表层一侧看，具有第一硬涂层和透明树脂薄膜层。第一层硬涂层由涂层材料形成，涂层材料包括：(A) 100 份（按重量计）多官能度（甲基）丙烯酸酯；(B) 1-100 份（按重量计）N-取代（甲基）丙烯酰胺化合物。透明树脂薄膜的第一层硬涂层形成面是聚（甲基）丙烯酸酰亚胺树脂。根据本发明另一实施例的硬涂层层压薄膜，从表层一侧看，具有第二硬涂层、第一硬涂层和透明树脂薄膜层。第二硬涂层由涂层材料形成，涂层材料包括：(A) 100 份（质量）的多官能度（甲基）丙烯酸酯；(E) 0.01-7 份（质量）的防水剂；和 (F) 0.01-10 份（质量）的硅烷偶联剂；不含无机颗粒。
• MOLDED BODY
  申请人：Riken Technos Corporation

  公开号：EP3272513A1

  公开（公告）日：2018-01-24

  One embodiment of the present invention is a molded body that comprises a resin substrate and in which: a part or all of the surface of the substrate is coated with a hard coat; a first hard coat is formed from a coating material that does not contain inorganic particles and that contains (A) 100 parts by mass of a polyfunctional (meth)acrylate, (B) 0.01-7 parts by mass of a water-repelling agent, and (C) 0.01-10 parts by mass of a silane coupling agent; and a second hard coat is formed from a coating material containing (A) 100 parts by mass of the polyfunctional (meth)acrylate and (D) 50-300 parts by mass of fine inorganic particles having an average particle size of 1-300 nm. Another embodiment of the present invention is a molded body that comprises a resin substrate and in which a part or all of the surface of the substrate is coated with a hard coat, a first hard coat is formed from a coating material that does not contain inorganic particles, a second hard coat is formed from a coating material containing inorganic particles, (i) the total light transmittance is 85% or more, and (ii) the pencil hardness of the surface of the first hard coat is 5H or more.

  本发明的一个实施例是一种模塑体，该模塑体包括树脂基材，其中：基材的部分或全部表面涂有硬涂层；第一层硬涂层由不含无机颗粒的涂层材料形成，该涂层材料含有(A) 100 份（质量）的多官能度（甲基）丙烯酸酯、(B) 0.01-7质量份的憎水剂，以及(C)0.01-10质量份的硅烷偶联剂；第二硬涂层由涂层材料形成，该涂层材料含有(A)100质量份的多官能度(甲基)丙烯酸酯，以及(D)50-300质量份的平均粒径为1-300纳米的细无机颗粒。本发明的另一个实施例是一种模塑体，它包括树脂基材，其中基材的部分或全部表面涂有硬涂层，第一硬涂层由不含无机颗粒的涂层材料形成，第二硬涂层由含无机颗粒的涂层材料形成，(i) 总透光率为 85% 或以上，(ii) 第一硬涂层表面的铅笔硬度为 5H 或以上。
• ANTI-GLARE HARD COAT LAMINATED FILM
  申请人：Riken Technos Corporation

  公开号：EP3272527A1

  公开（公告）日：2018-01-24

  One embodiment of the present invention is a hard coat laminated film having, in order from a surface layer side, a first hard coat and a transparent resin film layer. The first hard coat comprises a coating material not including inorganic particles and including: (A) 100 parts by mass polyfunctional (meth) acrylate; (B) 0.01-7 parts by mass water repellent; (C) 0.01-10 parts by mass silane coupling agent; and (D) 0.1-10 parts by mass resin microparticles having an average particle diameter of 0.5-10 µm. Another embodiment of the present invention is a hard coat laminated film having, in order from a surface layer side, a first hard coat, a second hard coat, and a resin film layer. The first hard coat comprises a coating material that does not include inorganic particles. The second hard coat comprises a coating material including inorganic particles. The adhesive film fulfills the conditions: (i) a total light transmission rate of at least 85%; (ii) a pencil hardness for the first hard coat surface of at least 5H; and (iii) a Y value for an XYZ color system of 1.5%-4.2%.

  本发明的一个实施方案是一种硬涂层层压薄膜，从表层一侧起依次具有第一硬涂层和透明树脂薄膜层。第一硬涂层由不包括无机颗粒的涂层材料组成，包括：(A) 100 重量份的多官能（甲基）丙烯酸酯；(B) 0.01-7 重量份的防水剂；(C) 0.01-10 重量份的硅烷偶联剂；以及 (D) 0.1-10 重量份的树脂微粒，其平均颗粒直径为 0.5-10 微米。本发明的另一个实施方案是一种硬涂层层压薄膜，从表层一侧起依次具有第一硬涂层、第二硬涂层和树脂薄膜层。第一硬涂层包括不含无机颗粒的涂层材料。第二硬涂层由包括无机颗粒的涂层材料组成。胶膜满足以下条件：(i) 总透光率至少为 85%；(ii) 第一硬涂层表面的铅笔硬度至少为 5H；(iii) XYZ 颜色系统的 Y 值为 1.5%-4.2%。
• HARD COAT LAMINATE FILM
  申请人：Riken Technos Corporation

  公开号：EP3406660A1

  公开（公告）日：2018-11-28

  The present invention is a hard coat laminate film that has, in order from a surface layer side, layers of a first hard coat and a transparent resin film. The first hard coat contains (A) 100 parts by mass of a multifunctional (meth)acrylate including 20 mass% or more of tripentaerythritol acrylate, and (B) 0.01-7 parts by mass of a (meth)acryloyl group-containing fluoropolyetherbased water repellent, and is formed from a paint not containing inorganic particles. The thickness of the hard coat laminated film is 5-60 µm. Component (A) may be a mixture of: tripentaerythritol acrylate; and at least one selected from the group consisting of dipentaerythritol acrylate, monopentaerythritol acrylate, and polypentaerythritol acrylate.

  本发明是一种硬涂层层压薄膜，从表层一侧起依次具有第一硬涂层层和透明树脂薄膜层。第一层硬涂层含有 (A) 100 份（质量份）多功能（甲基）丙烯酸酯，其中包括 20 份（质量份）以上的季戊四醇丙烯酸酯，以及 (B) 0.01-7 份（质量份）含（甲基）丙烯酰基的含氟聚醚基防水剂，并由不含无机颗粒的涂料形成。硬涂层层压膜的厚度为 5-60 微米。组分（A）可以是以下物质的混合物：季戊四醇丙烯酸酯；以及至少一种选自二季戊四醇丙烯酸酯、单季戊四醇丙烯酸酯和聚季戊四醇丙烯酸酯组成的组的物质。