2-[(Z)-2-(3-nitrophenyl)ethenyl]quinoline

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 2-[(Z)-2-(3-nitrophenyl)ethenyl]quinoline
• 化学式: C₁₇H₁₂N₂O₂
• 分子量: 276.294
• InChiKey: URIXDBULDXTIHZ-NTMALXAHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  21
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  58.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-[(Z)-2-(3-nitrophenyl)ethenyl]quinoline 以 乙腈 为溶剂， 生成 (E)-2-(3-nitrostyryl)quinoline
  参考文献：
  名称：

  Regiospecific C–N Photocyclization of 2-Styrylquinolines

  摘要：

  Regiospecific C-N photocyclization of 2-styrylquinolines resulting in formation of potentially biologically active quino[1,2-a]quinolizinium derivatives was investigated. The presence of strong electron-donating groups in the phenyl ring reveals to be a crucial factor managing photocyclization effectiveness. Introduction of a crown ether moiety allows changing the photoreaction parameters by means of complexation with Mg(ClO4)2.

  DOI：

  10.1021/jo500696n
• 作为产物：
  描述：

  (E)-2-(3-nitrostyryl)quinoline 以 乙腈 为溶剂， 生成 2-[(Z)-2-(3-nitrophenyl)ethenyl]quinoline
  参考文献：
  名称：

  Regiospecific C–N Photocyclization of 2-Styrylquinolines

  摘要：

  Regiospecific C-N photocyclization of 2-styrylquinolines resulting in formation of potentially biologically active quino[1,2-a]quinolizinium derivatives was investigated. The presence of strong electron-donating groups in the phenyl ring reveals to be a crucial factor managing photocyclization effectiveness. Introduction of a crown ether moiety allows changing the photoreaction parameters by means of complexation with Mg(ClO4)2.

  DOI：

  10.1021/jo500696n

文献信息

• Regiospecific C–N Photocyclization of 2-Styrylquinolines
  作者：Elena N. Gulakova、Daria V. Berdnikova、Tseimur M. Aliyeu、Yuri V. Fedorov、Ivan A. Godovikov、Olga A. Fedorova

  DOI：10.1021/jo500696n

  日期：2014.6.20

  Regiospecific C-N photocyclization of 2-styrylquinolines resulting in formation of potentially biologically active quino[1,2-a]quinolizinium derivatives was investigated. The presence of strong electron-donating groups in the phenyl ring reveals to be a crucial factor managing photocyclization effectiveness. Introduction of a crown ether moiety allows changing the photoreaction parameters by means of complexation with Mg(ClO4)2.