N-[8-(hexyloxy)octyl]isoquinolin-5-amine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: N-[8-(hexyloxy)octyl]isoquinolin-5-amine
• 英文别名: N-[8-(Hexyloxy)octyl]isoquinolin-5-amine；N-(8-hexoxyoctyl)isoquinolin-5-amine
• 化学式: C₂₃H₃₆N₂O
• 分子量: 356.552
• InChiKey: OVIKDWHPRZJULL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.8
• 重原子数：
  26
• 可旋转键数：
  15
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.61
• 拓扑面积：
  34.2
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  N-[8-(hexyloxy)octyl]quinolin-6-amine 、 8-(hexyloxy)octanoic acid 、 5-氨基异喹啉 生成 N-[8-(hexyloxy)octyl]isoquinolin-5-amine
  参考文献：
  名称：

  AMINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC, AND ANTICANCER ACTIVITY

  摘要：

  本文描述了对炎症、真菌、单细胞寄生微生物和癌症具有活性的胺化合物。这些化合物包含一个单环、双环或三环芳香环，其中含有一个、两个或三个环氮原子。

  公开号：

  US20150361077A1

文献信息

• Amine compounds having anti-inflammatory, antifungal, antiparasitic, and anticancer activity
  申请人：Wellstat Therapeutics Corporation

  公开号：US10030015B2

  公开（公告）日：2018-07-24

  Amine compounds having activity against inflammation, fungi, unicellular parasitic microorganisms, and cancer are described. The compounds contain a monocyclic, bicyclic, or tricyclic aromatic ring having one, two, or three ring nitrogen atoms.

  本文描述了具有抗炎、抗真菌、抗单细胞寄生微生物和抗癌活性的胺化合物。这些化合物含有单环、双环或三环芳香环，环上有一个、两个或三个氮原子。
• Aminoquinazoline compounds having anti-inflammatory, antifungal, antiparasitic, and anticancer activity
  申请人：Wellstat Therapeutics Corporation

  公开号：US10934284B2

  公开（公告）日：2021-03-02

  Amine compounds having activity against inflammation, fungi, unicellular parasitic microorganisms, and cancer are described. The compounds contain a monocyclic, bicyclic, or tricyclic aromatic ring having one, two, or three ring nitrogen atoms.

  本文描述了具有抗炎、抗真菌、抗单细胞寄生微生物和抗癌活性的胺化合物。这些化合物含有单环、双环或三环芳香环，环上有一个、两个或三个氮原子。
• AMINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC AND ANTICANCER ACTIVITY
  申请人：Wellstat Therapeutics Corporation

  公开号：EP2950649B1

  公开（公告）日：2020-03-04
• AMINOQUINOLINE COMPOUNDS HAVING ANTICANCER ACTIVITY
  申请人：Wellstat Therapeutics Corporation

  公开号：US20180298000A1

  公开（公告）日：2018-10-18

  Amine compounds having activity against inflammation, fungi, unicellular parasitic microorganisms, and cancer are described. The compounds contain a monocyclic, bicyclic, or tricyclic aromatic ring having one, two, or three ring nitrogen atoms.
• AMINOQUINAZOLINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC, AND ANTICANCER ACTIVITY
  申请人：Wellstat Therapeutics Corporation

  公开号：US20190194193A1

  公开（公告）日：2019-06-27

  Amine compounds having activity against inflammation, fungi, unicellular parasitic microorganisms, and cancer are described. The compounds contain a monocyclic, bicyclic, or tricyclic aromatic ring having one, two, or three ring nitrogen atoms.