1-acetyl-2-chloro-1,2-dihydroindol-3-one | 156386-05-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 1-acetyl-2-chloro-1,2-dihydroindol-3-one
• 英文别名: 1-acetyl-2-chloro-1,2-dihydro-3-H-indol-3-one；1-acetyl-2-chloro-2H-indol-3-one
• CAS: 156386-05-9
• 化学式: C₁₀H₈ClNO₂
• 分子量: 209.632
• InChiKey: IXKRCOMIAQLFPN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  14
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  37.4
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  硫脲 、 1-acetyl-2-chloro-1,2-dihydroindol-3-one 在 碘 作用下， 以 乙醇 为溶剂， 反应 1.0h， 以8%的产率得到1-(2-aminothiazolo[5,4-b]indol-4-yl)ethanone
  参考文献：
  名称：

  2-氨基-4 h-噻唑并[5,4- b ]吲哚的合成及其有色酪氨酸磷酸酶抑制活性的有色转化产物的表征

  摘要：

  在DMSO溶液中，将2-氨基-4 H-噻唑并[5,4- b ]吲哚转化为有色产物的复杂混合物。通过色谱法分离了三种主要的转化终产物，其中两种是蛋白酪氨酸磷酸酶（PTP）抑制剂，其结构通过光谱分析进行了表征，包括NMR和MS结合计算机辅助的结构解析，以及最后，通过独立的化学合成证实。描述了由氨基吲哚或2-溴-1-（2-硝基-苯基）乙酮制备的2-氨基-4 H-噻唑并[5，4- b ]吲哚及其N-乙酰基衍生物的合成。

  DOI：

  10.1002/jhet.5570380303
• 作为产物：
  描述：

  1-acetyl-2-phenyl-1H-indole-3-carbaldehyde 在 间氯过氧苯甲酸 作用下， 以 二氯甲烷 为溶剂， 反应 3.0h， 以48%的产率得到1-acetyl-2-chloro-1,2-dihydroindol-3-one
  参考文献：
  名称：

  A Convenient Synthesis of 1,2-Dihydro-3H-indol-3-ones and 1,2-Dihydro-2H-indol-2-ones by Baeyer-Villiger Oxidation

  摘要：

  取代的1H-吲哚-3-甲醛在Baeyer-Villiger重排作用下，得到了相应的取代的1,2-二氢-3H-吲哚-3-酮。研究了3-羰基和1-保护基团的影响。该反应已扩展到1H-吲哚-2-甲醛，并用于合成1-(苯磺酰基)-1H-吲哚-2-基三氟甲磺酸酯。

  DOI：

  10.1055/s-1994-25488

文献信息

• Ink set for inkjet recording and inkjet recording method
  申请人：FUJIFILM Corporation

  公开号：EP1975210A1

  公开（公告）日：2008-10-01

  An ink set for inkjet recording is provided that includes at least a colored liquid comprising at least a radically polymerizable compound, a photopolymerization initiator, and a colorant and an undercoat liquid comprising at least a radically polymerizable compound and a photopolymerization initiator, the undercoat liquid comprising a sensitizer represented by Formula (I) below. In Formula (I) above, X denotes O, S, or NR, n denotes 0 or 1, R denotes a hydrogen atom, an alkyl group, or an acyl group, and R1, R2, R3, R4, R5, R6, R7, and R8 independently denote a hydrogen atom or a monovalent substituent. There is also provided an inkjet recording method employing the ink set for inkjet recording, the method including a step of applying the undercoat liquid on top of a recording medium, a step of semi-curing the undercoat liquid, and a step of carrying out image formation by discharging the colored liquid on top of the semi-cured undercoat liquid.

  提供了一种用于喷墨记录的墨水组，它至少包括一种由至少一种可径向聚合的化合物、一种光聚合引发剂和一种着色剂组成的有色液体，以及一种由至少一种可径向聚合的化合物和一种光聚合引发剂组成的底层液体，底层液体包括由下式（I）代表的敏化剂。 在上式（I）中，X 表示 O、S 或 NR，n 表示 0 或 1，R 表示氢原子、烷基或酰基，R1、R2、R3、R4、R5、R6、R7 和 R8 独立地表示氢原子或单价取代基。还提供了一种喷墨记录方法，该方法采用了用于喷墨记录的墨水组，该方法包括在记录介质上涂敷底层液体的步骤、半固化底层液体的步骤，以及通过在半固化底层液体上排放有色液体来形成图像的步骤。
• Photocurable coating composition, and overprint and process for producing same
  申请人：FUJIFILM Corporation

  公开号：EP2042563A1

  公开（公告）日：2009-04-01

  A photocurable coating composition is provided that includes (A) a compound represented by Formula (I) below, (B) a photopolymerization initiator, and (C) a compound having an ethylenically unsaturated bond. (In Formula (I), X denotes O, S, or NR, n denotes an integer of 0 to 4, R denotes a hydrogen atom, an alkyl group, or an acyl group, R1 to R8 independently denote a hydrogen atom or a monovalent substituent, and R1 to R4 may form a ring in which two thereof that are adjacent are bonded to each other.) There are also provided an overprint having on an electrophotographically printed material an overprint layer in which the photocurable coating composition is photocured, and a process for producing the overprint that includes a step of obtaining an electrophotographically printed material by carrying out electrophotographic printing on a printing substrate, a step of coating the electrophotographically printed material with the photocurable coating composition, and a step of photocuring the photocurable coating composition.

  光固化涂料组合物包括 (A) 下式 (I) 所代表的化合物、(B) 光聚合引发剂和 (C) 具有乙烯不饱和键的化合物。 (在式(I)中，X 表示 O、S 或 NR，n 表示 0 至 4 的整数，R 表示氢原子、烷基或酰基，R1 至 R8 独立地表示氢原子或单价取代基，R1 至 R4 可形成其中相邻的两个相互键合的环)。 还提供了一种罩印，其在电致发光印刷材料上具有罩印层，在罩印层中光固化了光固化涂层组合物，还提供了一种生产罩印的工艺，该工艺包括通过在印刷基底上进行电致发光印刷获得电致发光印刷材料的步骤、在电致发光印刷材料上涂布光固化涂层组合物的步骤，以及对光固化涂层组合物进行光固化的步骤。
• Photocurable composition, photocurable ink composition, process for producing photocured material, and inkjet recording method
  申请人：FUJIFILM Corporation

  公开号：EP2085439A1

  公开（公告）日：2009-08-05

  A photocurable composition is provided that includes a polymerizable compound, a photopolymerization initiator, a compound represented by Formula (I) below, and an amine compound, the photopolymerization initiator comprising an acylphosphine oxide compound and/or an α-aminoacetophenone compound in Formula (I) above, X denotes O, S, or NR, n denotes 0 or 1, R denotes a hydrogen atom, an alkyl group, or an acyl group, R1, R2, R3, R4, R5, R6, R7, and R8 independently denote a hydrogen atom or a monovalent substituent, and two of R1, R2, R3, and R4 that are adjacent may be bonded to each other to form a ring. There are also provided a photocurable ink composition that includes the photocurable composition and a colorant, an ink composition for photocuring inkjet recording that includes the photocurable ink composition, a process for producing a photocured material that includes preparing the photocurable composition and irradiating the photocurable composition with light having a light emission peak in the range of at least 340 nm but no greater than 400 nm, and an inkjet recording method that includes discharging the ink composition onto a recording medium and irradiating the ink composition with actinic radiation.

  提供了一种光固化组合物，该组合物包括可聚合化合物、光聚合引发剂、下式 (I) 所代表的化合物和胺化合物，其中光聚合引发剂包括酰基氧化膦化合物和/或 α-氨基苯乙酮化合物 在上式（I）中，X 表示 O、S 或 NR，n 表示 0 或 1，R 表示氢原子、烷基或酰基，R1、R2、R3、R4、R5、R6、R7 和 R8 独立地表示氢原子或一价取代基，相邻的两个 R1、R2、R3 和 R4 可以相互键合形成环。还提供了一种光固化墨水组合物，它包括该光固化组合物和着色剂；一种用于光固化喷墨记录的墨水组合物，它包括该光固化墨水组合物；一种用于生产光固化材料的工艺，它包括制备该光固化组合物，并用在至少340纳米但不大于400纳米范围内具有光发射峰的光照射该光固化组合物；以及一种喷墨记录方法，它包括将墨水组合物排放到记录介质上，并用阳极辐射照射该墨水组合物。
• Photo-curable composition, ink composition, and inkjet recording method using the ink composition
  申请人：Fujifilm Corporation

  公开号：EP2145931A1

  公开（公告）日：2010-01-20

  A photo-curable composition including (A) a cationic polymerizable compound, (B) a sensitizing colorant represented by the following formula (1), and (C) an onium salt; an ink composition containing the photo-curable composition; an inkjet recording method using the ink composition are provided, and in formula (I), X represents O, S or NR, R represents a hydrogen atom, an alkyl group, or an acyl group, n represents 0 or 1, each of R1 to R8 independently represents a hydrogen atom, or a monovalent substituent.

  提供了一种光固化组合物，包括（A）阳离子可聚合化合物，（B）由下式（1）表示的感光着色剂和（C）鎓盐；一种含有该光固化组合物的墨水组合物；一种使用该墨水组合物的喷墨记录方法，在式(I)中，X代表O、S或NR，R代表氢原子、烷基或酰基，n代表0或1，R1至R8各自独立地代表氢原子或单价取代基。
• Ink-jet ink composition, and ink-jet recording method
  申请人：Fujifilm Corporation

  公开号：EP2154213A1

  公开（公告）日：2010-02-17

  An ink-jet ink composition containing the following components of (a), (b), and (c), and having a viscosity at 25°C in the range of from 5 mPa·s to 100 mPa·s, (a) a polymerizable compound, (b) a photopolymerization initiator, and (c) a sensitizer represented by the following formula (i): in the Formula (i), X represents O, S or NR; n represents an integer of 0 or 1; R represents a hydrogen atom, an alkyl group or an acyl group; each of R1, R2, R3, R4, R5, R6, R7 and R8 independently represents a hydrogen atom or a monovalent substituent, provided that any neighboring two of R1, R2, R3 and R4 may be bonded to each other to form a ring, and R5 and R7 or R8, or R6 and R7 or R8, may be bonded to each other to form an aliphatic ring but do not form an aromatic ring.

  一种喷墨墨水组合物，含有(a)、(b)和(c)中的下列成分，在 25℃时的粘度在 5 mPa-s 至 100 mPa-s 之间、 (a) 可聚合化合物、 (b) 光聚合引发剂，和 (c) 下式(i)所代表的敏化剂： 式（i）中，X 代表 O、S 或 NR；n 代表 0 或 1 的整数；R 代表氢原子、烷基或酰基；R1、R2、R3、R4、R5、R6、R7 和 R8 中的每一个独立地代表一个氢原子或一个一价取代基，但 R1、R2、R3 和 R4 中的任意相邻两个可相互键合形成一个环，R5 和 R7 或 R8 或 R6 和 R7 或 R8 可相互键合形成一个脂肪族环，但不形成一个芳香族环。