3-(benzyloxycarbonyl)-5-(decyloxycarbonyl)benzoic acid | 1318249-59-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-(benzyloxycarbonyl)-5-(decyloxycarbonyl)benzoic acid
• CAS: 1318249-59-0
• 化学式: C₂₆H₃₂O₆
• 分子量: 440.536
• InChiKey: KGDULARJHRURNI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.04
• 重原子数：
  32.0
• 可旋转键数：
  14.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  89.9
• 氢给体数：
  1.0
• 氢受体数：
  5.0

反应信息

• 作为反应物：
  描述：

  3-(benzyloxycarbonyl)-5-(decyloxycarbonyl)benzoic acid 在 吡啶 、 palladium on carbon 、 氢气 、 三氟乙酸 、 potassium hydroxide 作用下， 以 四氢呋喃 、 甲醇 、 二氯甲烷 、 乙酸乙酯 为溶剂， 反应 19.16h， 生成
  参考文献：
  名称：

  Synthesis and duplex formation of the reverse amidohelicene tetramer

  摘要：

  The reverse amidohelicene (P)-tetramer containing (P)-helicenediamine and m-phenylenedicarboxylate was synthesized. The circular dichroism (CD) and vapor pressure osmometry (VPO) analysis revealed the dimeric aggregate formation in THF. It is notable that the reverse amide tetramer formed a duplex, as well as the original amidohelicene oligomers. In various solutions, mixtures of the reverse (P)-tetramer and amidohelicene (P)/(M)-tetramer formed homoaggregates instead of heteroaggregates. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2011.05.059
• 作为产物：
  描述：

  癸基溴 在 碳酸氢钠 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 33.5h， 生成 3-(benzyloxycarbonyl)-5-(decyloxycarbonyl)benzoic acid
  参考文献：
  名称：

  Synthesis and duplex formation of the reverse amidohelicene tetramer

  摘要：

  The reverse amidohelicene (P)-tetramer containing (P)-helicenediamine and m-phenylenedicarboxylate was synthesized. The circular dichroism (CD) and vapor pressure osmometry (VPO) analysis revealed the dimeric aggregate formation in THF. It is notable that the reverse amide tetramer formed a duplex, as well as the original amidohelicene oligomers. In various solutions, mixtures of the reverse (P)-tetramer and amidohelicene (P)/(M)-tetramer formed homoaggregates instead of heteroaggregates. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2011.05.059

文献信息

• Synthesis and duplex formation of the reverse amidohelicene tetramer
  作者：Wataru Ichinose、Masamichi Miyagawa、Jun Ito、Masanori Shigeno、Ryo Amemiya、Masahiko Yamaguchi

  DOI：10.1016/j.tet.2011.05.059

  日期：2011.7

  The reverse amidohelicene (P)-tetramer containing (P)-helicenediamine and m-phenylenedicarboxylate was synthesized. The circular dichroism (CD) and vapor pressure osmometry (VPO) analysis revealed the dimeric aggregate formation in THF. It is notable that the reverse amide tetramer formed a duplex, as well as the original amidohelicene oligomers. In various solutions, mixtures of the reverse (P)-tetramer and amidohelicene (P)/(M)-tetramer formed homoaggregates instead of heteroaggregates. (C) 2011 Elsevier Ltd. All rights reserved.