2-benzyloxymethyl-2-ethoxycarbonylcyclopentanone | 41938-73-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-benzyloxymethyl-2-ethoxycarbonylcyclopentanone
• 英文别名: Ethyl 2-oxo-1-(phenylmethoxymethyl)cyclopentane-1-carboxylate
• CAS: 41938-73-2
• 化学式: C₁₆H₂₀O₄
• 分子量: 276.332
• InChiKey: JDOJLLAUXRVYHU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  20
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2-benzyloxymethyl-2-ethoxycarbonylcyclopentanone 在 palladium on activated charcoal 4-二甲氨基吡啶 、 lithium aluminium tetrahydride 、 氢气 、 对甲苯磺酸 、 溶剂黄146 作用下， 以 四氢呋喃 、 吡啶 、 甲醇 、 乙醚 、 水 、 苯 为溶剂， 反应 15.5h， 生成 3-Methyl-butyric acid 2-oxo-1-(toluene-4-sulfonyloxymethyl)-cyclopentylmethyl ester
  参考文献：
  名称：

  Fang, Chenglin; Suganuma, Kyoko; Suemune, Hiroshi, Journal of the Chemical Society. Perkin transactions I, 1991, # 6, p. 1549 - 1554

  摘要：

  DOI：
• 作为产物：
  描述：

  苄基氯甲基醚 、 2-氧代环戊羧酸乙酯 在 potassium tert-butylate 作用下， 生成 2-benzyloxymethyl-2-ethoxycarbonylcyclopentanone
  参考文献：
  名称：

  Fang, Chenglin; Suganuma, Kyoko; Suemune, Hiroshi, Journal of the Chemical Society. Perkin transactions I, 1991, # 6, p. 1549 - 1554

  摘要：

  DOI：

文献信息

• CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND APPLICATION THEREOF
  申请人：Beijing Lihe Technology Ltd.

  公开号：US20170283530A1

  公开（公告）日：2017-10-05

  Provided is a solid catalyst component for olefin polymerization, which comprises Mg, Ti, a halogen and an electron donor. The electron donor is selected from at least one of ring-substituted ether-acid ester compounds of the general formula (I). Also provided are a catalyst containing the solid catalyst component and the application of the catalyst in reactions of olefin polymerization, particularly in the reaction of propylene polymerization.

  提供了一种用于烯烃聚合的固体催化剂组分，包括镁、钛、卤素和电子给体。电子给体从通式（I）的环取代醚酸酯化合物中至少选择一个。还提供了含有该固体催化剂组分的催化剂以及在烯烃聚合反应中应用该催化剂的方法，特别是在丙烯聚合反应中的应用。
• Enzymatic hydrolysis of 2,2-bis(acetoxymethyl)cycloalkanones, and its application to formal synthesis of(-)-malyngolide.
  作者：HIROSHI SUEMUNE、TETSUJI HARABE、ZHUO-FENG XIE、KIYOSHI SAKAI

  DOI：10.1248/cpb.36.4337

  日期：——

  Asymmetric hydrolysis of 2, 2-bis (acetoxymethyl) cyclopentanone (5) using biocatalysts and its application to a formal synthesis of (-)-malyngolide are described.For the asymmetric induction at the quaternary carbon of 5, cholinesterase from electric eel was found to be effective to afford the (+)-monoacetate (6)(90%ee).Compound (+)-6 was easily converted to the synthetic intermediate (28) for (-)-malyngolide.

  介绍了利用生物催化剂对 2，2-双（乙酰氧甲基）环戊酮（5）进行不对称水解，并将其应用于 (-)-malyngolide 的正式合成。在 5 的季碳上进行不对称诱导时，发现来自电鳗的胆碱酯酶能有效地生成 (+)- 单乙酸酯 (6)（90%ee）。
• Catalyst component for olefin polymerization and application thereof
  申请人：Beijing Lihe Technology Ltd.

  公开号：US10208146B2

  公开（公告）日：2019-02-19

  Provided is a solid catalyst component for olefin polymerization, which comprises Mg, Ti, a halogen and an electron donor. The electron donor is selected from at least one of ring-substituted ether-acid ester compounds of the general formula (I). Also provided are a catalyst containing the solid catalyst component and the application of the catalyst in reactions of olefin polymerization, particularly in the reaction of propylene polymerization.

  本发明提供了一种用于烯烃聚合的固体催化剂组分，它由 Mg、Ti、卤素和电子供体组成。电子供体选自通式（I）的环取代醚酸酯化合物中的至少一种。此外，还提供了一种含有固体催化剂组分的催化剂，以及该催化剂在烯烃聚合反应，特别是丙烯聚合反应中的应用。
• SUEMUNE, HIROSHI;HARABE, TETSUJI;XIE, ZHUO-FENG;SAKAI, KIYOSHI, CHEM. AND PHARM. BULL., 36,(1988) N1, C. 4337-4344
  作者：SUEMUNE, HIROSHI、HARABE, TETSUJI、XIE, ZHUO-FENG、SAKAI, KIYOSHI

  DOI：——

  日期：——
• OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF
  申请人：Renqiu Lihe Technology Ltd.

  公开号：US20170355792A1

  公开（公告）日：2017-12-14

  Provided is an olefin polymerization catalyst carrier with a general structure formula of Mg(OR I ) n (OR II ) 2-n , wherein: 0≦n≦2, and R I and R II can be the same or different and are each independently selected from a C 1 -C 20 hydrocarbon group. In the X-ray diffraction pattern of the catalyst carrier, there are a set of diffraction peaks in the range of a 2θ diffraction angle of 5°-15°, and the set of diffraction peaks contain 1-4 main diffraction peaks. Also disclosed is an olefin polymerization solid catalyst component which is prepared from the carrier Mg(OR I ) n (OR II ) 2-n , a titanium compound, and at least one electron donor compound. In addition, also disclosed is an olefin polymerization catalyst containing the solid catalyst component, at least one organic aluminum compound, and optionally, an external electron donor compound.