3-(hydroxymethyl)-13-crown-4 | 92818-17-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3-(hydroxymethyl)-13-crown-4
• 英文别名: 1,4,7,10-Tetraoxacyclotridec-12-ylmethanol
• CAS: 92818-17-2
• 化学式: C₁₀H₂₀O₅
• 分子量: 220.266
• InChiKey: NIMKAQKBLVTVHN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1
• 重原子数：
  15
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  57.2
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  3-(hydroxymethyl)-13-crown-4 在 sodium hydride 作用下， 以 四氢呋喃 、 吡啶 为溶剂， 反应 72.0h， 生成 12-methylene-1,4,7,10-tetraoxacyclotridecane
  参考文献：
  名称：

  Czech, Bronislaw P.; Czech, Anna; Son, Byungki, Journal of Heterocyclic Chemistry, 1986, vol. 23, p. 465 - 471

  摘要：

  DOI：
• 作为产物：
  描述：

  12-methylene-1,4,7,10-tetraoxacyclotridecane 在 sodium hydroxide 、 dimethyl sulfide borane 、 双氧水 作用下， 生成 3-(hydroxymethyl)-13-crown-4
  参考文献：
  名称：

  Functionalized 13-crown-4, 14-crown-4, 15-crown-4, and 16-crown-4 compounds: synthesis and lithium ion complexation

  摘要：

  DOI：

  10.1021/jo00199a011

文献信息

• Ring Size Effect of Crown Ether on the Fixation of Carbon Dioxide into an Oxirane Polymer
  作者：Shin-ichi Yamamoto、Osamu Moriya、Takeshi Endo

  DOI：10.1021/ma040131a

  日期：2005.3.1

  Several methacrylate derivatives having a crown ether group, the size of which was changed from 12-crown-4 to 16-crown-5, were newly prepared and copolymerized with glycidyl methacrylate under radical conditions. The obtained copolymers (CP1-5) were employed for the fixation of CO2 into the oxirane moieties using lithium salt as a catalyst. The conversion of oxirane to five-membered cyclic carbonate groups by fixation of CO2 was related with the ring size of crown ethers and reflected the association constants for Li+. The most efficient fixation of CO2 in nitromethane solution was observed in the use of CP3, having 14-crown-4 groups, in which oxirane groups were transformed into the corresponding cyclic carbonate groups quantitatively, and further, the reaction proceeded readily even in the solid state.
• Functionalized 13-crown-4, 14-crown-4, 15-crown-4, and 16-crown-4 compounds: synthesis and lithium ion complexation
  作者：Bronislaw P. Czech、David A. Babb、Byungki Son、Richard A. Bartsch

  DOI：10.1021/jo00199a011

  日期：1984.12
• Czech, Bronislaw P.; Czech, Anna; Son, Byungki, Journal of Heterocyclic Chemistry, 1986, vol. 23, p. 465 - 471
  作者：Czech, Bronislaw P.、Czech, Anna、Son, Byungki、Lee, Han Koo、Bartsch, Richard A.

  DOI：——

  日期：——