(4,4-dibromobutyl)benzene | 83483-27-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (4,4-dibromobutyl)benzene
• 英文别名: 4,4-dibromobutylbenzene
• CAS: 83483-27-6
• 化学式: C₁₀H₁₂Br₂
• 分子量: 292.013
• InChiKey: QLLLXJPZUWXKLE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  (4,4-dibromobutyl)benzene 、 联硼酸频那醇酯 在 copper(l) iodide 、 lithium methanolate 、 三苯基膦 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 24.0h， 以94%的产率得到2,2'-(4-phenylbutane-1,1-diyl)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane)
  参考文献：
  名称：

  A Catalytic Enantiotopic-Group-Selective Suzuki Reaction for the Construction of Chiral Organoboronates

  摘要：

  Catalytic enantiotopic-group-selective cross-couplings of achiral geminal bis(pinacolboronates) provide a route for the construction of nonracemic chiral organoboronates. In the presence of a chiral monodentate taddol-derived phosphoramidite ligand, these reactions occur with high levels of asymmetric induction. Mechanistic experiments with chiral B-10-enriched geminal bis(boronates) suggest that the reaction occurs by a stereochemistry-determining transmetalation that occurs with inversion of configuration at carbon.

  DOI：

  10.1021/ja500029w
• 作为产物：
  描述：

  4,4-Bis(phenyltellanyl)butylbenzene 在 溴 、 sodium bromide 作用下， 以81%的产率得到(4,4-dibromobutyl)benzene
  参考文献：
  名称：

  PREPARATION OF ALKYL HALIDES VIA ORGANOTELLURIUMS

  摘要：

  苯基碲烷转化为卤代烷的研究与烷基卤的同系化有关。1,1-二(苯基碲)烷的类似反应为醛类提供了一种新的合成方法。

  DOI：

  10.1246/cl.1982.1081

文献信息

• Electrooxidative Activation of B−B Bond in B ₂ cat ₂ : Access to <i>gem</i> ‐Diborylalkanes via Paired Electrolysis
  作者：Bingbing Wang、Xiangyu Zhang、Yangmin Cao、Long Zou、Xiaotian Qi、Qingquan Lu

  DOI：10.1002/anie.202218179

  日期：2023.3.27

  electrooxidation of a solvent (e.g., DMF)-ligated B2cat2 complex, whereby a solvent-stabilized boryl radical is formed via quasi-homolytic cleavage of the B−B bond in a DMF-ligated B2cat2 radical cation. Furthermore, a strategy for the electrochemical gem-diborylation of gem-bromides via paired electrolysis is developed for the first time, affording a range of versatile gem-diborylalkanes.

  该报告描述了溶剂（例如 DMF）连接的 B 2 cat 2络合物前所未有的电氧化，由此通过 DMF 连接的 B 2 cat中B−B 键的准均裂裂解形成溶剂稳定的硼基自由基2自由基阳离子。此外，首次开发了一种通过配对电解对宝石-溴化物进行电化学宝石-二硼基化的策略，提供了一系列通用的宝石-二硼基烷烃。
• Rapid and Practical Synthesis of <i>gem</i>‐Dibromoalkanes from Aldehydes by Tribromide Reagent
  作者：Bowen Ren、Jianeng Xu、Chao Liu

  DOI：10.1002/asia.202301087

  日期：2024.3

  A rapid and practical synthesis of gem-dibromoalkanes has been developed. A variety of alkyl and aromatic aldehydes are converted into their corresponding gem-dibromoalkanes within 10 minutes by using tribromide reagent. The protocol is also appliable to the bromination of alcohols, accessing alkyl bromides with inversion of configuration.

  已经开发出一种快速且实用的宝石二溴烷烃合成方法。利用三溴化物试剂，多种烷基醛和芳香醛在10分钟内转化为相应的偕二溴烷烃。该方案也适用于醇的溴化，通过构型反转获得烷基溴。
• Method for producing an aromatic compound having an alkyl group with at least three carbon atoms
  申请人：TORAY INDUSTRIES, INC.

  公开号：EP0985649A2

  公开（公告）日：2000-03-15

  Aromatic compounds having an alkyl group with at least 3 carbon atoms are produced in a process comprising at least one of the following steps: (1) a step of contacting a starting material that contains an aromatic compound having a branched alkyl group with at least 3 carbon atoms, with a zeolite-containing catalyst in a liquid phase in the presence of hydrogen therein, thereby changing the position of the carbon atoms of the alkyl group bonding to the aromatic ring of the compound; (2) a step of contacting a starting material that contains an aromatic compound having a branched alkyl group with at least 3 carbon atoms, with a catalyst containing zeolite and containing rhenium and/or silver, in a liquid phase, thereby changing the position of the carbon atoms of the alkyl group bonding to the aromatic ring of the compound; (3) a step of contacting a halogenated aromatic compound having an alkyl group with at least 3 carbon atoms, with an acid-type catalyst, thereby isomerizing the compound; and (4) a step of treating a mixture of isomers of an aromatic compound having an alkyl group with at least 3 carbon atoms, with a zeolite adsorbent that contains at least one exchangable cation selected from alkali metals, alkaline earth metals, lead, thallium and silver, thereby separating a specific isomer from the isomer mixture through adsorption.

  具有至少 3 个碳原子烷基的芳香族化合物的生产工艺至少包括以下一个步骤： (1) 将含有至少 3 个碳原子的支链烷基的芳香族化合物的起始原料在液相中与含沸石的催化剂在氢存在的情况下接触，从而改变烷基的碳原子与化合物的芳香环键合的位置； (2) 将含有芳香族化合物的起始原料与含沸石和含铼和/或银的催化剂在液相中接触，该芳香族化合物具有至少 3 个碳原子的支链烷基，从而改变烷基碳原子与化合物芳香环键合的位置； (3) 将具有至少 3 个碳原子的烷基的卤代芳香族化合物与酸型催化剂接触，从而使该化合物异构化；以及 (4) 用沸石吸附剂处理具有至少 3 个碳原子的烷基的芳香族化合物的异构体混合物，该沸石吸附剂含有至少一种选自碱金属、碱土金属、铅、铊和银的可交换阳离子，从而通过吸附从异构体混合物中分离出特定的异构体。
• POLYISOCYANATE COMPOSITION AND ISOCYANATE POLYMER COMPOSITION
  申请人：Asahi Kasei Chemicals Corporation

  公开号：EP2915803A1

  公开（公告）日：2015-09-09

  The present invention relates to a polyisocyanate composition comprising, on the basis of the total mass of the polyisocyanate composition, 97 weight % or more of a polyisocyanate, and 2.0 mass ppm or more and 1.0×104 mass ppm or less of a compound having at least one unsaturated bond in which the compound is a different compound from the polyisocyanate, or 5.0 mass ppm or more and 2.0×104 mass ppm or less of at least one inactive compound selected from the group consisting of a hydrocarbon compound, an ether compound, a sulfide compound, a halogenated hydrocarbon compound, a Si-containing hydrocarbon compound, a Si-containing ether compound, and a Si-containing sulfide compound.

  本发明涉及一种多异氰酸酯组合物，以该多异氰酸酯组合物的总质量为基准，该组合物包含 97 重量％或以上的多异氰酸酯，以及 2.0 质量 ppm 或以上且 1.0×104 质量 ppm 或以下的至少具有一个不饱和键的化合物，其中该化合物是与多异氰酸酯不同的化合物，或 5.0 质量 ppm 或以上且 2.0×104 质量 ppm 或以下的至少一种非活性化合物，该化合物选 自烃化合物、醚化合物、硫化物化合物、卤代烃化合物、含硅烃化合物、含硅醚化合物和含硅硫 化物组成的组。
• ISOCYANATE COMPOSITION, ISOCYANATE POLYMER PRODUCTION METHOD, AND ISOCYANATE POLYMER
  申请人：ASAHI KASEI KABUSHIKI KAISHA

  公开号：EP3527603A1

  公开（公告）日：2019-08-21

  The present invention provides an isocyanate composition including an isocyanate compound having an ethylenically unsaturated bond, a compound represented by formula (1) (in the formula, R1 represents an a-valent organic group, R2 represents a monovalent organic group, a represents an integer of 1 or 2), and/or a compound having a UV absorption in a spectral region of a decamer or higher isocyanate measured by gel permeation chromatography; and an isocyanate composition including an isocyanate compound having an ethylenically unsaturated bond, or a compound having at least one unsaturated bond other than an unsaturated bond constituting an aromatic ring or an inert compound such as a hydrocarbon compound or the like and having a carbon-carbon unsaturated bond other than an unsaturated bond constituting an aromatic ring; or the like.         R1-(COO-R2)a     (1)

  本发明提供了一种异氰酸酯组合物，包括具有乙烯不饱和键的异氰酸酯化合物、由式(1)代表的化合物（式中，R1代表一价有机基团，R2代表一价有机基团，a代表1或2的整数），和/或通过凝胶渗透色谱法测量在十聚体或更高异氰酸酯光谱区具有紫外吸收的化合物；异氰酸酯组合物，包括具有乙烯不饱和键的异氰酸酯化合物，或具有至少一个不饱和键（构成芳香环的不饱和键除外）的化合物，或惰性化合物（如烃类化合物等），且具有碳-碳不饱和键（构成芳香环的不饱和键除外）的化合物；或类似物。 R1-(COO-R2)a (1)