1′,2,3,3′,4,4′,6-hepta-O-benzyl-6′-amino-6′-deoxysucrose | 1613526-83-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1′,2,3,3′,4,4′,6-hepta-O-benzyl-6′-amino-6′-deoxysucrose
• 英文别名: [(2R,3R,4S,5S)-3,4-bis(phenylmethoxy)-5-(phenylmethoxymethyl)-5-[(2R,3R,4S,5R,6R)-3,4,5-tris(phenylmethoxy)-6-(phenylmethoxymethyl)oxan-2-yl]oxyoxolan-2-yl]methanamine
• CAS: 1613526-83-2
• 化学式: C₆₁H₆₅NO₁₀
• 分子量: 972.188
• InChiKey: XSORAUHHVXFGPD-FZPLEZICSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.4
• 重原子数：
  72
• 可旋转键数：
  26
• 环数：
  9.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  118
• 氢给体数：
  1
• 氢受体数：
  11

反应信息

• 作为反应物：
  描述：

  1′,2,3,3′,4,4′,6-hepta-O-benzyl-6′-amino-6′-deoxysucrose 、 甲基丙烯酰氯 在 4-二甲氨基吡啶 、 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 2.33h， 以70%的产率得到N-(methacrylamido)-1′,2,3,3′,4,4′,6-hepta-O-benzyl-6′-amino-6′-deoxysucrose
  参考文献：
  名称：

  Amide-linked N-methacryloyl sucrose containing polymers

  摘要：

  1',2,3,3',4,4',6-Hepta-O-benzyl-6'-N-methacryloyl-6'-deoxysucrose 1, 6'-deoxy-6'-N-methacryloyloxyethylureido sucrose 2 and 6,6'-dideoxy-6,6'-N-dimethacryloyloxyethylureido sucrose 3 have been homo-polymerized and copolymerized with styrene by a free radical process, yielding polymer materials with pendant sucrose moieties, attached to the polymer backbone via amide linkages. The results demonstrated that varying the structural features of the monomers, greatly affected the thermal and rheological properties of the polymers. The polymer materials obtained have been characterized by NMR, MALDI-TOF, DSC, AFM and EWC (equilibrium water content). The efficient synthesis of the three novel, regioisomerically pure, N-methacryloylamide sucrose-containing monomers (1, 2 and 3) have been described. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carbpol.2014.03.050
• 作为产物：
  描述：

  1′,2,3,3′,4,4′,6-hepta-O-benzyl-6′-azido-6′-deoxysucrose 在 三苯基膦 作用下， 以 四氢呋喃 、 水 为溶剂， 反应 3.0h， 以89%的产率得到1′,2,3,3′,4,4′,6-hepta-O-benzyl-6′-amino-6′-deoxysucrose
  参考文献：
  名称：

  Amide-linked N-methacryloyl sucrose containing polymers

  摘要：

  1',2,3,3',4,4',6-Hepta-O-benzyl-6'-N-methacryloyl-6'-deoxysucrose 1, 6'-deoxy-6'-N-methacryloyloxyethylureido sucrose 2 and 6,6'-dideoxy-6,6'-N-dimethacryloyloxyethylureido sucrose 3 have been homo-polymerized and copolymerized with styrene by a free radical process, yielding polymer materials with pendant sucrose moieties, attached to the polymer backbone via amide linkages. The results demonstrated that varying the structural features of the monomers, greatly affected the thermal and rheological properties of the polymers. The polymer materials obtained have been characterized by NMR, MALDI-TOF, DSC, AFM and EWC (equilibrium water content). The efficient synthesis of the three novel, regioisomerically pure, N-methacryloylamide sucrose-containing monomers (1, 2 and 3) have been described. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carbpol.2014.03.050