The present invention relates to compounds of the formula (I):
1
wherein:
Het represents a heterocyclic residue selected from:
2
where the dotted line in (b) represents an optional double bond;
A completes a fused pyridine ring; and
B completes a fused benzene or pyridine ring.
The compounds are of particular use in the treatment or prevention of depression, anxiety, pain, inflammation, migaine, emesis or postherpetic neuralgia.
本发明涉及公式(I)的化合物:1其中:Het代表从以下选择的杂环残基:2其中(b)中的虚线表示可选的双键;A完成了一个融合的
吡啶环;B完成了一个融合的苯环或
吡啶环。这些化合物在治疗或预防抑郁症、焦虑症、疼痛、炎症、偏头痛、呕吐或带状疱疹后神经痛方面具有特殊用途。