(+/-)-7,12-dimethylbenzanthracene-cis-5S,6R-dihydrodiol

• 分子结构分类: 有机化合物 - 苯类化合物 - 菲及其衍生物
• 英文名称: (+/-)-7,12-dimethylbenzanthracene-cis-5S,6R-dihydrodiol
• 英文别名: 7,12-dimethylbenzanthracene-trans-5,6-dihydro-5,6-diol；(+/-)-7,12-dimethybenzanthracene cis-5,6-dihydrodiol；5,6-Dihydroxy-7,12-dimethyl-5,6-dihydro-benzanthracen；(+/-)-cis-5.6-dihydroxy-7.12-dimethyl-5.6-dihydro-benz[a]anthracene；(+/-)-5r.6c-Dihydroxy-7.12-dimethyl-5.6-dihydro-benz[a]anthracen；(+/-)-cis-5.6-Dihydroxy-7.12-dimethyl-5.6-dihydro-benz[a]anthracen；(5R,6S)-7,12-dimethyl-5,6-dihydrobenzo[a]anthracene-5,6-diol
• 化学式: C₂₀H₁₈O₂
• 分子量: 290.362
• InChiKey: SGVWCDYKBWRHKJ-UXHICEINSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  22
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

上下游信息

反应信息

• 作为反应物：
  描述：

  (+/-)-7,12-dimethylbenzanthracene-cis-5S,6R-dihydrodiol 在 盐酸 、 溶剂黄146 作用下， 生成 5-Methoxy-7,12-dimethylbenzanthracen
  参考文献：
  名称：

  42.四氧化锇氧化致癌碳氢化合物

  摘要：

  DOI：

  10.1039/jr9480000170
• 作为产物：
  描述：

  7,12-二甲基苯并[a]蒽 在 吡啶 、 四氧化锇 作用下， 生成 (+/-)-7,12-dimethylbenzanthracene-cis-5S,6R-dihydrodiol
  参考文献：
  名称：

  Synthesis of the enantiomeric K-region arene 5,6-oxides derived from chrysene, 7,12-dimethylbenz[a]anthracene, and benzo[c]phenanthrene

  摘要：

  DOI：

  10.1021/jo00377a025

文献信息

• Solvolysis of K-region arene oxides: substituent effects on reactions of benz[a]anthracene 5,6-oxide
  作者：Nashaat T. Nashed、Suresh K. Balani、Richard J. Loncharich、Jane M. Sayer、David Y. Shipley、Ram S. Mohan、Dale L. Whalen、Donald M. Jerina

  DOI：10.1021/ja00010a036

  日期：1991.5

  dioxane-water and in methanol at 25 o C are reported. These substitutions result in >150-fold differences in their rates of acid-catalyzed solvolysis and cause marked changes in the distribution of solvent adducts and phenols resulting from isomerization. Optically pure BA-O, 7-MBA-O, 12-MBA-O, and 7,12-DMBA-O as well as their optically pure trans dihydrodiols were utilized to determine the point of attack by

  苯并 [a] 蒽 5,6-氧化物 (BA-O) 在取代 1 (1-MBA-O)、4 (4-MBA-O)、7 ( 7-MBA-O)、11 (11-MBA-O) 和 12 (12-MBA-O)、7,12-二甲基取代 (7,12-DMBA-O) 和 7-溴取代1:9 二恶烷-水和甲醇在 25 o C 报告。这些取代导致其酸催化溶剂分解的速率差异 > 150 倍，并导致异构化导致的溶剂加合物和酚类的分布发生显着变化。利用光学纯的 BA-O、7-MBA-O、12-MBA-O 和 7,12-DMBA-O 以及它们的光学纯反式二氢二醇来确定水解反应中水的攻击点
• Resolution and absolute configuration of K-region trans dihydrodiols from polycyclic aromatic hydrocarbons
  作者：S. K. Balani、P. J. Van Bladeren、N. Shirai、D. M. Jerina

  DOI：10.1021/jo00360a024

  日期：1986.5
• Human–computer interface design issues for a multi-cultural and multi-lingual English speaking country — Botswana
  作者：E.A Onibere、S Morgan、E.M Busang、D Mpoeleng

  DOI：10.1016/s0953-5438(00)00052-7

  日期：2001.4

  This paper reports on research carried out to determine whether a localised interface is preferred by users in a multi-cultural and multi-lingual country where a non-local language is nationally used,. We attempted to discover whether local symbols are more acceptable to users as icons and also whether the current phrases used in menus and icon descriptions are clearly understood by the various communities.A survey was conducted nation-wide among computer end-users in Botswana. The results indicate an overwhelming desire from users for a localised interface. However, there appears to be little need for localised icons and no agreement as to which language to use for text-based interfaces. (C) 2001 Elsevier Science B.V. All rights reserved.
• K Region Fission and Addition Products of 7,12-Dimethylbenz[a]anthracene¹
  作者：HERBERT I. HADLER、ALLEN C. KRYGER

  DOI：10.1021/jo01081a018

  日期：1960.11
• K-Region<i>trans</i>-Dihydrodiols of Polycyclic Arenes; An Efficient and Convenient Preparation from<i>o</i>-Quinones or<i>o</i>-Diphenols by Reduction with Sodium Borohydride in the Presence of Oxygen
  作者：Karl L. Platt、Franz Oesch

  DOI：10.1055/s-1982-29834

  日期：——