4-羟基己-1-烯-3-酮 | 22082-45-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 4-羟基己-1-烯-3-酮
• 英文名称: 4-hydroxy-1-hexen-3-one
• 英文别名: 4-hydroxy-hex-1-en-3-one；4-Hydroxyhex-1-en-3-one
• CAS: 22082-45-7
• 化学式: C₆H₁₀O₂
• 分子量: 114.144
• InChiKey: ZWFSKVZACXTELI-UHFFFAOYSA-N

物化性质

• 沸点：
  179.6±23.0 °C(Predicted)
• 密度：
  0.969±0.06 g/cm3(Predicted)
• 保留指数：
  1430

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  8
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  硫代苯甲酰胺 、 4-羟基己-1-烯-3-酮 在 三氟化硼乙醚 作用下， 以 四氢呋喃 、 氯仿 为溶剂， 生成 4-(1-hydroxy-propyl)-2-phenyl-5,6-dihydro-4H-[1,3]thiazin-4-ol
  参考文献：
  名称：

  取代的6 H -1,3-噻嗪的合成

  摘要：

  一方面，由α，β-不饱和醛，酮和酮醇之间的BF 3醚酸酯催化的反应可以高收率制备取代的4,5-二氢-4-羟基-6 H -1,3-噻嗪II。硫酰胺，硫脲和二硫代氨基甲酸酯。

  DOI：

  10.1002/recl.19730920610
• 作为产物：
  描述：

  1-Aethyl-1-hydroxy-2-methoxy-butadien-(2,3) 在 硫酸 作用下， 生成 4-羟基己-1-烯-3-酮
  参考文献：
  名称：

  Hoff,S. et al., Recueil des Travaux Chimiques des Pays-Bas, 1968, vol. 87, p. 1179 - 1184

  摘要：

  DOI：

文献信息

• Preparation of pyrazines
  申请人：SOCIETE DES PRODUITS NESTLE S.A.

  公开号：EP1357193A1

  公开（公告）日：2003-10-29

  The present invention relates to a new process for the generation of pyrazines consisting in the bioconversion of hydroxyketones with 1,2-diaminopropane. New tetrahydropyrazine derivatives as well as new dihydropyrazine derivatives with high flavour and low threshold properties are disclosed. Such pyrazines compounds exhibiting roasted and earthy aroma profiles may be used in the food and bevererage industry, especially chocolate, confectionery and coffee.

  本发明涉及一种生成吡嗪类化合物的新工艺，该工艺包括通过1,2-二氨基丙烷对羟基酮的生物转化。公开了新的四氢吡嗪衍生物以及新的二氢吡嗪衍生物，这些衍生物具有浓郁的风味和低阈值特性。这些呈现烤制和泥土香味的吡嗪化合物可用于食品和饮料行业，特别是用于巧克力、糖果和咖啡。
• Chemoenzymatic Synthesis of Aroma Active 5,6-Dihydro- and Tetrahydropyrazines from Aliphatic Acyloins Produced by Baker's Yeast
  作者：Toshinari Kurniadi、Rachid Bel Rhlid、Laurent-Bernard Fay、Marcel-Alexandre Juillerat、Ralf Günter Berger

  DOI：10.1021/jf0261809

  日期：2003.5.1

  Twenty-five acyloins were generated by biotransformation of aliphatic aldehydes and 2-ketocarboxylic acids using whole cells of baker's yeast as catalyst. Six of these acyloins were synthesized and tentatively characterized for the first time. Subsequent chemical reaction with 1,2-propanediamine under mild conditions resulted in the formation of thirteen 5,6-dihydropyrazines and six tetrahydropyrazines

  以面包酵母的整个细胞为催化剂，通过脂肪族醛和2-酮羧酸的生物转化，产生了二十五个酰化甘油。首次合成了其中的六种酰基辅酶，并对其进行了初步鉴定。随后在温和的条件下与1,2-丙二胺发生化学反应，导致形成了十三种5,6-二氢吡嗪和六种四氢吡嗪。对它们的气味质量进行了评估，并估计了它们的气味阈值。在这些吡嗪衍生物中，2-乙基-3,5-二甲基-5,6-二氢吡嗪（烤，坚果，0.002 ng / L空气），2,3-二乙基-5-甲基-5,6-二氢吡嗪（烤，空气中的浓度为0.004 ng / L）和2-乙基-3,5-二甲基四氢吡嗪（面包类面包皮，空气中的浓度为1.9 ng / L）是气味最强烈的活性化合物。
• Blends of comb-shaped copolymers of a macromolecular monomer of polylactone with polymer (s)
  申请人：THE B.F. GOODRICH COMPANY

  公开号：EP0539655A2

  公开（公告）日：1993-05-05

  Blends are formed with numerous commercially available resins and a comb-shaped polymer ("comb" for brevity) of a macromolecular monomer of a polylactone having terminal vinyl unsaturation so long as the polylactone chains are long enough to be compatible with one of the components to be blended. The comb may be formed with any polymerizable olefinically unsaturated monomer, preferably a vinyl, styryl, or acryloyl monomer. The vinyl unsaturation of the "head" of the macromer of polylactone may be acryloyl, styryl or allyl. The comb is made by a low temperature emulsion or suspension polymerization process. The comb, which has a hydrocarbon backbone and pendant polylactone chains, typically has a number average molecular weight of at least 10,000. A blend of first and second resins which are normally incompatible with each other, is also produced using a comb in which the backbone is compatible with one of the resins. Such blends also result with a synthetic resin and a comb in which the pendant chains consist of a first block which has a polylactone structure, and a second block which has a polyether structure, or vice versa.

  混合物是由多种市售树脂和一种梳状聚合物（简称 "梳子"）形成的，梳子是由具有乙烯基不饱和末端的聚内酯大分子单体组成，只要聚内酯链足够长，能与其中一种要混合的成分相容即可。梳子可以用任何可聚合的烯烃不饱和单体形成，最好是乙烯基、苯乙烯基或丙烯酰基单体。聚乳酸大单体 "头部 "的乙烯基不饱和度可以是丙烯酰基、苯乙烯基或烯丙基。梳子是通过低温乳液或悬浮聚合工艺制成的。梳子具有烃骨架和下垂的聚乳酸链，其平均分子量通常至少为 10,000。使用骨架与其中一种树脂相容的梳子，还可以生产出通常互不相容的第一种和第二种树脂的混合物。使用合成树脂和梳子也可以产生这种混合物，其中的垂链由具有聚乳酮结构的第一嵌段和具有聚醚结构的第二嵌段组成，反之亦然。
• RESIN COMPOSITION AND HEAT-RESISTANT ADHESIVE
  申请人：Otsuka Chemical Co., Ltd.

  公开号：EP2009030A1

  公开（公告）日：2008-12-31

  1. A resin composition containing a copolymer which is obtained by copolymerizing 80 to 99.9 parts by weight of a vinyl monomer mainly containing a (meth)acrylic acid alkyl ester and 0.1 to 20 parts by weight of a vinyl monomer having a reactive functional group by living radical polymerization, while using, as a polymerization initiator, one of the following: (a) to (d), (a) an organotellurium compound of the formula (1); (b) a mixture of an organotellurium compound of the formula (1) and an azo polymerization initiator; (c) a mixture of an organotellurium compound of the formula (1) and an organoditellurium compound of the formula (2); and (d) a mixture of an organotellurium compound of the formula (1), an azo polymerization initiator and an organoditellurium compound of the formula (2), and which is further characterized in that the metal content in the composition is not more than 1000 ppm wherein R1 is C1-C8 alkyl, aryl group, substituted aryl or aromatic heterocyclic group; R2 and R3 are respectively a hydrogen atom or C1-C8 alkyl; and R4 is aryl, substituted aryl, aromatic heterocyclic group, acyl, amide, oxycarbonyl or cyano         (R1Te)2     (2) wherein R1 is as defined above.

  一种含有共聚物的树脂组合物，该共聚物是由 80 至 99.9（重量份）主要含有（甲基）丙烯酸烷基酯的乙烯基单体和 0.1 至 20（重量份）具有活性官能团的乙烯基单体通过活自由基聚合反应共聚而成，同时作为聚合引发剂使用以下其中一种：(a)至(d)、 (a) 式(1)的有机碲化合物； (b) 式(1)的有机碲化合物与偶氮聚合引发剂的混合物； (c) 式(1)的有机碲化合物与式(2)的有机二碲化合物的混合物；及 (d) 式(1)的有机碲化合物、偶氮聚合引发剂和式(2)的有机二碲化合物的混合物、 其进一步特征在于，组合物中的金属含量不超过 1000ppm 其中 R1 是 C1-C8 烷基、芳基、取代芳基或芳香杂环基团；R2 和 R3 分别是氢原子或 C1-C8 烷基；R4 是芳基、取代芳基、芳香杂环基团、酰基、酰胺、氧羰基或氰基。 (R1Te)2 (2) 其中 R1 如上定义。
• Heat resistance improver and reversible thermosensitive recording medium
  申请人：Ricoh Company, Ltd.

  公开号：EP2103445A1

  公开（公告）日：2009-09-23

  A heat resistance improver including a heat resistance improving component which has a benzotriazole skeleton having an electron attractive group and a reactive aliphatic hydroxyl group or a reactive aliphatic mercapto group, wherein the heat resistance improver is used in a reversible thermosensitive recording medium.

  一种耐热性改进剂，包括一种具有苯并三唑骨架的耐热性改进成分，该骨架具有一个引电子基团和一个反应性脂肪族羟基或反应性脂肪族巯基，其中耐热性改进剂用于可逆热敏记录介质。