A compound of the formula (I): wherein A is a hydrogen atom, an optionally substituted, unsaturated, N-containing heterocyclic group or a group of the formula (a): wherein R is an optionally substituted aryl group or an optionally substituted heterocyclic group; M is —(CH
2
)n-, —(CH
2
)n-O—(CH
2
)m-or —(CH
2
)n-NH—(CH
2
)m-, wherein n and m are independently 0, 1 or 2; Q is an optionally substituted cycloalkylene group, an optionally substituted arylene group or an optionally substituted divalent heterocyclic group; and the moiety of the formula (b): is an optionally substituted, unsaturated, mono-, di-, tri- or tetra-cyclic, N-containing heterocyclic group which may contain additional hetero atom(s) selected from the group consisting of nitrogen, oxygen and sulfur atoms as the ring member(s), its prodrug or a pharmaceutically acceptable salt thereof.
公式(I)的化合物:其中A是
氢原子,一个可选地取代的、不饱和的、含
氮的杂环基团,或者公式(a)的基团:其中R是一个可选地取代的芳香族基团或者一个可选地取代的杂环基团;M是—(
CH2)n-, —( )n-O—( )m-或—( )n-NH—( )m-,其中n和m各自为0、1或2;Q是一个可选地取代的
环烷基
烯基团、一个可选地取代的芳香族基团或者一个可选地取代的二价杂环基团;以及公式(b)的部分:是一个可选地取代的、不饱和的、单环、双环、
三环或四环的、含
氮的杂环基团,它可以包含作为环成员的额外杂原子,选自由
氮、
氧和
硫原子组成的组,其前药或药用盐。