(Z)-4-phenyloct-3-en-2-one | 91667-25-3

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: (Z)-4-phenyloct-3-en-2-one
• CAS: 91667-25-3
• 化学式: C₁₄H₁₈O
• 分子量: 202.296
• InChiKey: YZPJHJOODDXGRA-KAMYIIQDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  15
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  3-(甲基氨基)-1-苯基丁-2-烯-1-酮 、 正丁基氯化镁 在 cerium(III) chloride 作用下， 生成 (Z)-4-phenyloct-3-en-2-one
  参考文献：
  名称：

  Highly stereoselective synthesis of αβ-unsaturated ketones by CeCl₃mediated addition of grignard reagents to β-enamino ketones

  摘要：

  通过干燥的三氯化铈作为媒介，实现了格氏试剂对β-烯胺酮的直接加成，从而进行αβ-不饱和酮的选择性立体合成，并且观察到引入的骨架与羰基之间主要呈反式关系。

  DOI：

  10.1039/c39940000715

文献信息

• Lewis Acid Catalyzed Ring‐Opening Reaction of Cyclobutanones towards Conjugated Enones
  作者：Min Zhang、Jiqiang Gao、Jinbo Zhao、Tingtian Qiu、Zhongjuan Li、Ziteng Guo、Chunhui Liu、Yu Liu

  DOI：10.1002/ejoc.202101335

  日期：2021.12.7

  An unprecedented Fe-catalyzed ring-opening reaction of simple cyclobutanones was disclosed. Such a novel approach gives access to substituted conjugate enones with good functional group tolerance in high yields under mild conditions.

  公开了一种前所未有的铁催化的简单环丁酮的开环反应。这种新方法可以在温和条件下以高产率获得具有良好官能团耐受性的取代共轭烯酮。
• PULMONARY OCCLUSAL STENT DELIVERY CATHETER AND LOADING SYSTEM
  申请人：Pulmonx

  公开号：EP3295990A2

  公开（公告）日：2018-03-21

  Methods, systems and devices are described for performing lung volume reduction in patients suffering from chronic obstructive pulmonary disease or other conditions where isolation of a lung segment or reduction of lung volume is desired. The methods are minimally invasive with instruments being introduced through the mouth (endotracheally) and rely on isolating the target lung tissue segment from other regions of the lung and occluding various lung passageways with the use of occlusal stents (46). The occlusal stents are delivered with the use of an occlusal stent delivery system (10) which is loaded with the occlusal stent with the use of an occlusal stent loading system (130).

  本文描述的方法、系统和设备用于在慢性阻塞性肺病患者或其他需要隔离肺段或减少肺容量的情况下减少肺容量。这些方法是微创的，通过口腔（气管内）导入器械，依靠将目标肺组织区段与肺部其他区域隔离，并使用咬合支架咬合各种肺部通道 (46)。使用咬合支架输送系统（10）输送咬合支架，使用咬合支架装载系统（130）装载咬合支架。
• Fluid charging mechanism for balloon catheter system
  申请人：Aundal T. Knud

  公开号：US20050187430A1

  公开（公告）日：2005-08-25

  In general, the invention is directed to a balloon catheter system for intra-luminal or intra-cavity pressure measurements. In accordance with the invention, the balloon catheter system provides a closed fluid charging mechanism to charge and discharge a balloon mounted on the catheter. More particularly, the charging mechanism may include a closed reservoir, a passage, and an actuator that acts to drive fluid out of the reservoir and through the passage. A lumen within a catheter may transport fluid from the passage to charge the balloon. The pressure monitoring catheter system may take pressure measurements when the balloon is charged. Discharging the balloon may include withdrawing the actuator from the charging mechanism, which fills the reservoir with fluid from the balloon. In addition, a seal member may be used in the pressure monitoring catheter system to provide a more sealed environment for holding and transporting fluid.

  总的来说，本发明涉及一种用于腔内或腔内压力测量的球囊导管系统。根据本发明，球囊导管系统提供了一个封闭的流体充注机构，用于充注和排放安装在导管上的球囊。更具体地说，充注机构可包括一个封闭的储液器、一个通道和一个驱动流体从储液器中流出并通过通道的致动器。导管内的管腔可从通道中输送流体，为球囊充能。压力监测导管系统可在球囊充气时进行压力测量。排出球囊可包括将致动器从充气机构中撤出，从而用来自球囊的流体填充储液器。此外，压力监测导管系统中还可使用密封部件，为容纳和输送流体提供更加密封的环境。
• Pulmonary occlusal stent delivery catheter, loading system and methods of use
  申请人：Wondka Anthony

  公开号：US20060162731A1

  公开（公告）日：2006-07-27

  Methods, systems and devices are provided for performing lung volume reduction in patients suffering from chronic obstructive pulmonary disease or other conditions where isolation of a lung segment or reduction of lung volume is desired. The methods are minimally invasive with instruments being introduced through the mouth (endotracheally) and rely on isolating the target lung tissue segment from other regions of the lung and occluding various lung passageways with the use of occlusal stents. The occlusal stents are delivered with the use of an occlusal stent delivery system which is loaded with the occlusal stent with the use of an occlusal stent loading system.

  本文提供了一些方法、系统和设备，用于在慢性阻塞性肺病患者或其他需要隔离肺段或减少肺容量的情况下减少肺容量。这些方法是微创的，通过口腔（气管内）导入器械，依靠将目标肺组织区段与肺部其他区域隔离，并使用咬合支架咬合各种肺部通道。使用咬合支架输送系统输送咬合支架，使用咬合支架装载系统装载咬合支架。
• Bartoli Giuseppe, Cimarelli Cristina, Marcantoni Enrico, Palmieri Gianni,+, J. Chem. Soc. Chem. Commun, (1994) N 6, S 715-716
  作者：Bartoli Giuseppe, Cimarelli Cristina, Marcantoni Enrico, Palmieri Gianni,+

  DOI：——

  日期：——