(2S,3S,4R,5R,6S)-2-methyl-6-[(2S,3S,4R,5R,6S)-2-methyl-6-[(2S,3S,4R,5R,6R)-2-methyl-4,5-bis(phenylmethoxy)-6-prop-2-enoxyoxan-3-yl]oxy-4,5-bis(phenylmethoxy)oxan-3-yl]oxy-4,5-bis(phenylmethoxy)oxan-3-ol | 127085-21-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2S,3S,4R,5R,6S)-2-methyl-6-[(2S,3S,4R,5R,6S)-2-methyl-6-[(2S,3S,4R,5R,6R)-2-methyl-4,5-bis(phenylmethoxy)-6-prop-2-enoxyoxan-3-yl]oxy-4,5-bis(phenylmethoxy)oxan-3-yl]oxy-4,5-bis(phenylmethoxy)oxan-3-ol
• CAS: 127085-21-6
• 化学式: C₆₃H₇₂O₁₃
• 分子量: 1037.26
• InChiKey: DFBIUVZVELEAGX-AQDVPVAHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  10.07
• 重原子数：
  76.0
• 可旋转键数：
  25.0
• 环数：
  9.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  130.99
• 氢给体数：
  1.0
• 氢受体数：
  13.0

反应信息

• 作为反应物：
  描述：

  [(2S,3S,4R,5R,6S)-6-[(2S,3S,4R,5R,6S)-6-[(2S,3S,4R,5R,6S)-6-chloro-2-methyl-4,5-bis(phenylmethoxy)oxan-3-yl]oxy-2-methyl-4,5-bis(phenylmethoxy)oxan-3-yl]oxy-2-methyl-4,5-bis(phenylmethoxy)oxan-3-yl] acetate 、 (2S,3S,4R,5R,6S)-2-methyl-6-[(2S,3S,4R,5R,6S)-2-methyl-6-[(2S,3S,4R,5R,6R)-2-methyl-4,5-bis(phenylmethoxy)-6-prop-2-enoxyoxan-3-yl]oxy-4,5-bis(phenylmethoxy)oxan-3-yl]oxy-4,5-bis(phenylmethoxy)oxan-3-ol 在 2-苯基-1-丙烯 作用下， 以60%的产率得到
  参考文献：
  名称：

  Total synthesis of cyclo-l-rhamnohexaose by a stereoselective thermal glycosylation

  摘要：

  The first cyclooligosaccharide of L series, cyclo-L-rhamnohexaose, have been synthesized from L-rhamnose by alpha-selective thermal glycosylation and PhSeOTf promoted cycloglycosylation.

  DOI：

  10.1016/0040-4039(91)80081-g
• 作为产物：
  描述：

  [(2S,3S,4R,5R,6S)-2-methyl-6-[(2S,3S,4R,5R,6S)-2-methyl-6-[(2S,3S,4R,5R,6R)-2-methyl-4,5-bis(phenylmethoxy)-6-prop-2-enoxyoxan-3-yl]oxy-4,5-bis(phenylmethoxy)oxan-3-yl]oxy-4,5-bis(phenylmethoxy)oxan-3-yl] acetate 在 sodium methylate 作用下， 以 甲醇 为溶剂， 以78%的产率得到(2S,3S,4R,5R,6S)-2-methyl-6-[(2S,3S,4R,5R,6S)-2-methyl-6-[(2S,3S,4R,5R,6R)-2-methyl-4,5-bis(phenylmethoxy)-6-prop-2-enoxyoxan-3-yl]oxy-4,5-bis(phenylmethoxy)oxan-3-yl]oxy-4,5-bis(phenylmethoxy)oxan-3-ol
  参考文献：
  名称：

  Total synthesis of cyclo-l-rhamnohexaose by a stereoselective thermal glycosylation

  摘要：

  The first cyclooligosaccharide of L series, cyclo-L-rhamnohexaose, have been synthesized from L-rhamnose by alpha-selective thermal glycosylation and PhSeOTf promoted cycloglycosylation.

  DOI：

  10.1016/0040-4039(91)80081-g