(1R,6R,7S,11R,12R,17R,18S,22R)-9,9,20,20-tetramethyl-3,14-bis(prop-2-ynyl)-8,10,19,21,23,24-hexaoxa-3,14-diazapentacyclo[15.5.1.16,12.07,11.018,22]tetracosane | 1207452-38-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (1R,6R,7S,11R,12R,17R,18S,22R)-9,9,20,20-tetramethyl-3,14-bis(prop-2-ynyl)-8,10,19,21,23,24-hexaoxa-3,14-diazapentacyclo[15.5.1.16,12.07,11.018,22]tetracosane
• CAS: 1207452-38-7
• 化学式: C₂₆H₃₈N₂O₆
• 分子量: 474.598
• InChiKey: PEGUHQQSMMXJLS-HKHZPIFNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  34
• 可旋转键数：
  2
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.85
• 拓扑面积：
  61.9
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  (1R,6R,7S,11R,12R,17R,18S,22R)-9,9,20,20-tetramethyl-3,14-bis(prop-2-ynyl)-8,10,19,21,23,24-hexaoxa-3,14-diazapentacyclo[15.5.1.16,12.07,11.018,22]tetracosane 、 9,10-bis(azidomethyl)anthracene 在 copper(l) iodide 、 三苯基膦 作用下， 以 甲苯 为溶剂， 反应 0.25h， 以35%的产率得到
  参考文献：
  名称：

  Synthesis of a sugar-aza-crown ether-based cavitand as a selective fluorescent chemosensor for Cu2+ ion

  摘要：

  A chemosensor based upon the sugar-aza-crown ether 7 with one anthracenetriazolymethyl moiety was prepared and its fluoroionophoric properties toward transition metal ions were investigated. Chemosensor 7 exhibits highly selective recognition toward Cu2+ ion among a series of tested metal ions in MeOH solution. The association constant for 7*Cu2+ in MeOH solution was calculated to be 2.5 x 10(4) M-1. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.10.093
• 作为产物：
  描述：

  sugar-aza-crown ether 、 3-溴丙炔 在 四丁基碘化铵 、 potassium carbonate 、 potassium iodide 作用下， 以 乙腈 为溶剂， 生成 (1R,6R,7S,11R,12R,17R,18S,22R)-9,9,20,20-tetramethyl-3,14-bis(prop-2-ynyl)-8,10,19,21,23,24-hexaoxa-3,14-diazapentacyclo[15.5.1.16,12.07,11.018,22]tetracosane
  参考文献：
  名称：

  Synthesis of a sugar-aza-crown ether-based cavitand as a selective fluorescent chemosensor for Cu2+ ion

  摘要：

  A chemosensor based upon the sugar-aza-crown ether 7 with one anthracenetriazolymethyl moiety was prepared and its fluoroionophoric properties toward transition metal ions were investigated. Chemosensor 7 exhibits highly selective recognition toward Cu2+ ion among a series of tested metal ions in MeOH solution. The association constant for 7*Cu2+ in MeOH solution was calculated to be 2.5 x 10(4) M-1. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.10.093

文献信息

• Synthesis of a sugar-aza-crown ether-based cavitand as a selective fluorescent chemosensor for Cu2+ ion
  作者：Yu-Chi Hsieh、Jiun-Ly Chir、Hsiu-Han Wu、Chao-QI Guo、An-Tai Wu

  DOI：10.1016/j.tetlet.2009.10.093

  日期：2010.1

  A chemosensor based upon the sugar-aza-crown ether 7 with one anthracenetriazolymethyl moiety was prepared and its fluoroionophoric properties toward transition metal ions were investigated. Chemosensor 7 exhibits highly selective recognition toward Cu2+ ion among a series of tested metal ions in MeOH solution. The association constant for 7*Cu2+ in MeOH solution was calculated to be 2.5 x 10(4) M-1. (C) 2009 Elsevier Ltd. All rights reserved.