(E)-3-trifluoromethyl-2-butylpropenal

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (E)-3-trifluoromethyl-2-butylpropenal
• 英文别名: (2E)-2-(2,2,2-trifluoroethylidene)hexanal
• 化学式: C₈H₁₁F₃O
• 分子量: 180.17
• InChiKey: BJIATPNBSAZVAG-FNORWQNLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  正己醛 、 1-乙氧基-2,2,2-三氟乙醇 在 1-ethyl-3-methyl-1H-imidazolium trifluoromethane-sulfonate 、 三甲基硅烷基二乙胺 作用下， 生成 (E)-3-trifluoromethyl-2-butylpropenal 、 (Z)-3-trifluoromethyl-2-butylpropenal
  参考文献：
  名称：

  One step synthesis of 2-substituted 3-tri-(or di-)fluoromethyl-2-propenals in an ionic liquid

  摘要：

  Investigation of one step synthesis of 2-substituted 3-tri-(or di-)fluoromethyl-2-propenals has been carried out using versatile aldehydes, tri- or di-fluoroacetaldehyde ethyl hemiacetal in the presence of diethylaminotrimethylsilane (DEATMS) in an ionic liquid, and it was demonstrated that this route enabled us to successfully construct 2-substituted 3-tri-(or di-)fluoromethyl-2-propenals with the high level selectivity of geometric isomers. (C) 2003 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jfluchem.2003.10.010

文献信息

• One step synthesis of 2-substituted 3-tri-(or di-)fluoromethyl-2-propenals in an ionic liquid
  作者：Tomoya Kitazume、Hirokatsu Nagura、Shinichi Koguchi

  DOI：10.1016/j.jfluchem.2003.10.010

  日期：2004.1

  Investigation of one step synthesis of 2-substituted 3-tri-(or di-)fluoromethyl-2-propenals has been carried out using versatile aldehydes, tri- or di-fluoroacetaldehyde ethyl hemiacetal in the presence of diethylaminotrimethylsilane (DEATMS) in an ionic liquid, and it was demonstrated that this route enabled us to successfully construct 2-substituted 3-tri-(or di-)fluoromethyl-2-propenals with the high level selectivity of geometric isomers. (C) 2003 Elsevier B.V. All rights reserved.