(2S,4R)-4-tert-butyldimethylsiloxy-2-hydroxymethyl-N-(4-nitrobenzyloxycarbonyl) pyrrolidine | 104795-10-0

分子结构分类

有机化合物 - 苯类化合物 - 苯和取代衍生物

中文名称

——

中文别名

——

英文名称

(2S,4R)-4-tert-butyldimethylsiloxy-2-hydroxymethyl-N-(4-nitrobenzyloxycarbonyl) pyrrolidine

英文别名

(2S,4R)-4-t-butyldimethylsilyloxy-2-hydroxymethyl-1-(4-nitrobenzyloxycarbonyl)pyrrolidine；(2S, 4R)-4-t-butyldimethylsilyloxy-2-hydroxymethyl-1-(4-nitrobenzyloxycarbonyl)pyrrolidine；(4-nitrophenyl)methyl (2S,4R)-4-[tert-butyl(dimethyl)silyl]oxy-2-(hydroxymethyl)pyrrolidine-1-carboxylate

(2S,4R)-4-tert-butyldimethylsiloxy-2-hydroxymethyl-N-(4-nitrobenzyloxycarbonyl) pyrrolidine化学式

CAS

104795-10-0

化学式

C₁₉H₃₀N₂O₆Si

mdl

——

分子量

410.542

InChiKey

CPKDIECVFGDXFK-DLBZAZTESA-N

BEILSTEIN

——

EINECS

——

计算性质

辛醇/水分配系数(LogP)：

3.69
重原子数：

28
可旋转键数：

7
环数：

2.0
sp3杂化的碳原子比例：

0.63
拓扑面积：

105
氢给体数：

1
氢受体数：

6

上下游信息

上游原料

中文名称	英文名称	CAS号	化学式	分子量
——	(2S,4R)-4-tert-butyldimethylsiloxy-N-(4-nitrobenzyloxycarbonyl) proline methyl ester	117811-69-5	C₂₀H₃₀N₂O₇Si	438.553
1,2-二羧基吡咯烷酸,4-羟基-1-[(4-硝基苯基)甲基]酯	(2S,4R)-4-Hydroxy-1-(4-nitrobenzyloxycarbonyl)pyrrolidine-2-carboxylic acid	96034-57-0	C₁₃H₁₄N₂O₇	310.263
——	(2S,4R)-4-hydroxy-2-methoxycarbonyl-1-(4-nitrobenzyloxycarbonyl)pyrrolidine	101803-29-6	C₁₄H₁₆N₂O₇	324.29

下游产品

中文名称	英文名称	CAS号	化学式	分子量
——	(2S,4R)-2-formyl-4-tert-butyldimethylsilyloxy-1-(4-nitrobenzyloxycarbonyl)pyrrolidine	137049-21-9	C₁₉H₂₈N₂O₆Si	408.527
——	(2S,4R)-4-tert-butyldimethylsilyloxy-2-methanesulfonyloxymethyl-1-(4-nitrobenzyloxycarbonyl)pyrrolidine	127812-53-7	C₂₀H₃₂N₂O₈SSi	488.634
——	(2S,4R)-4-tert-butyldimethylsilyloxy-2-(imidazol-1-yl)methyl-1-(4-nitrobenzyloxycarbonyl)pyrrolidine	127812-54-8	C₂₂H₃₂N₄O₅Si	460.605
——	(2S,4R)-2-carboxymethyloxymethyl-4-hydroxy-1-(4-nitrobenzyloxycarbonyl)pyrrolidine	117811-73-1	C₁₅H₁₈N₂O₈	354.317
——	(2S,4R)-2-(1-carboxy-1-methylethyl)oxymethyl-4-hydroxy-1-(4-nitrobenzyloxycarbonyl)pyrrolidine	117811-56-0	C₁₇H₂₂N₂O₈	382.37
——	(2S,4R)-2-[2-(dimethylamino)ethyloxymethyl]-4-methanesulfonyloxy-1-(4-nitrobenzyloxycarbonyl)pyrrolidine	127767-90-2	C₁₈H₂₇N₃O₈S	445.494
——	(2S,4R)-4-methanesulfonyloxy-2-[2-{N-methyl-N-(4-nitrobenzyloxycarbonyl)amino}ethyloxymethyl]-1-(4-nitrobenzyloxycarbonyl)pyrrolidine	127767-91-3	C₂₅H₃₀N₄O₁₂S	610.599
——	(2S,4R)-4-methanesulfonyloxy-1-(4-nitrobenzyloxycarbonyl)-2-[2-(4-nitrobenzyloxycarbonylamino)ethyloxymethyl]pyrrolidine	199998-80-6	C₂₄H₂₈N₄O₁₂S	596.572
——	(2S,4R)-2-(2-hydroxyethyloxymethyl)-4-methanesulfonyloxy-1-(4-nitrobenzyloxycarbonyl)pyrrolidine	127767-87-7	C₁₆H₂₂N₂O₉S	418.425
——	(2S,4R)-2-(carboxymethyloxymethyl)-4-methanesulfonyloxy-1-(4-nitrobenzyloxycarbonyl)pyrrolidine	117811-74-2	C₁₆H₂₀N₂O₁₀S	432.408
——	(2S,4R)-2-Carbamoylmethyloxymethyl-4-methanesulfonyloxy-1-(4-nitrobenzyloxycarbonyl)pyrrolidine	117811-75-3	C₁₆H₂₁N₃O₉S	431.423
——	(2S,4R)-4-methanesulfonyloxy-2-(methylcarbamoyl)methyloxymethyl-1-(4-nitrobenzyloxycarbonyl)pyrrolidine	127767-89-9	C₁₇H₂₃N₃O₉S	445.45
——	(2S,4R)-2-(dimethylcarbamoyl)methyloxymethyl-4-methanesulfonyloxy-1-(4-nitrobenzyloxycarbonyl)pyrrolidine	127767-88-8	C₁₈H₂₅N₃O₉S	459.477
——	(2S,4R)-2-(allyloxycarbonylmethyloxymethyl)-4-methanesulfonyloxy-1-(4-nitrobenzyloxycarbonyl)pyrrolidine	127767-92-4	C₁₉H₂₄N₂O₁₀S	472.473
——	(2S,4R)-2-(1-carbamoyl-1-methylethyl)oxymethyl-4-methanesulfonyloxy-1-(4-nitrobenzyloxycarbonyl)pyrrolidine	117811-57-1	C₁₈H₂₅N₃O₉S	459.477
——	(2S,4S)-2-[2-(Dimethylamino)ethyloxymethyl]-4-mercapto-1-(4-nitrobenzyloxycarbonyl)pyrrolidine	127768-01-8	C₁₇H₂₅N₃O₅S	383.469
——	(2S,4S)-4-Mercapto-2-[2-(N-methyl-N-(4-nitrobenzyloxycarbonyl)amino) ethyloxymethyl]-1-(4-nitrobenzyloxycarbonyl)pyrrolidine	127768-02-9	C₂₄H₂₈N₄O₉S	548.574
——	(2S,4S)-4-Mercapto-2-(methylcarbamoyl)methyloxymethyl-(4-nitrobenzyloxycarbonyl)pyrrolidine	127768-00-7	C₁₆H₂₁N₃O₆S	383.425
——	(2S,4R)-4-hydroxy-2-(imidazol-1-yl)methyl-1-(4-nitrobenzyloxycarbonyl)pyrrolidine	127812-56-0	C₁₆H₁₈N₄O₅	346.343
——	(2S,4S)-2-(Dimethylcarbamoyl)methyloxymethyl-4-mercapto-1-(4-nitrobenzyloxycarbonyl)pyrrolidine	127767-99-1	C₁₇H₂₃N₃O₆S	397.452
——	(2S,4S)-2-allyloxycarbonylmethyloxymethyl-4-mercapto-1-(4-nitrobenzyloxycarbonyl)pyrrolidine	127768-03-0	C₁₈H₂₂N₂O₇S	410.448
——	(2S,4R)-4-t-butyldimethylsilyloxy-1-chloroacetyl-2-(hydroxymethyl)pyrrolidine	117811-70-8	C₁₃H₂₆ClNO₃Si	307.893
——	(2S,4S)-4-acetylthio-2-(2-hydroxy-ethyloxymethyl)-1-(4-nitrobenzyloxycarbonyl)pyrrolidine	199998-90-8	C₁₇H₂₂N₂O₇S	398.437
——	(2S,4S)-4-Acetylthio-2-[2-(dimethylamino)ethyloxymethyl]-1-(4-nitrobenzyloxycarbonyl)pyrrolidine	127767-96-8	C₁₉H₂₇N₃O₆S	425.506
——	(2S,4S)-4-Acetylthio-2-[2-{N-methyl-N-(4-nitrobenzyloxycarbonyl)amino}ethyloxymethyl]-1-(4-nitrobenzyloxycarbonyl)pyrrolidine	199998-92-0	C₂₆H₃₀N₄O₁₀S	590.611
——	(2S,4S)-4-acetylthio-1-(4-nitrobenzyloxycarbonyl)-2-[2-(4-nitrobenzyloxycarbonylamino)ethyloxymethyl]pyrrolidine	199998-91-9	C₂₅H₂₈N₄O₁₀S	576.584
——	(6S,8R)-8-t-butyldimethylsilyloxy-2-oxo-1-aza-4-oxabicyclo[4.3.0]nonane	117811-71-9	C₁₃H₂₅NO₃Si	271.432
——	(2S,4S)-4-acetylthio-2-(carbamoylmethyl)oxymethyl-1-(4nitrobenzyloxycarbonyl)pyrrolidine	199998-88-4	C₁₇H₂₁N₃O₇S	411.436
——	(2S,4R)-1-(2-bromo-2-methylpropionyl)-4-t-butyldimethylsilyloxy-2-(hydroxymethyl)pyrrolidine	117811-65-1	C₁₅H₃₀BrNO₃Si	380.398
——	(2S,4S)-4-Acetylthio-2-(methylcarbamoyl)methyloxymethyl-1-(4-nitrobenzyloxycarbonyl)pyrrolidine	127767-95-7	C₁₈H₂₃N₃O₇S	425.463