4-(5-bromo-2,4-dimethoxy-phenyl)-4-oxo-butyric acid | 63213-40-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 4-(5-bromo-2,4-dimethoxy-phenyl)-4-oxo-butyric acid
• 英文别名: 4-(5-Brom-2,4-dimethoxy-phenyl)-4-oxo-buttersaeure；β-(5-Brom-2.4-dimethoxy-benzoyl)-propionsaeure；4-(5-bromo-2,4-dimethoxyphenyl)-4-oxobutanoic acid
• CAS: 63213-40-1
• 化学式: C₁₂H₁₃BrO₅
• 分子量: 317.136
• InChiKey: CHSQSYHHJXGOTA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  18
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  72.8
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  4-(2-hydroxy-4-methoxyphenyl)-4-oxobutanoic acid 在 溴 、 potassium carbonate 、 丙酮 作用下， 生成 4-(5-bromo-2,4-dimethoxy-phenyl)-4-oxo-butyric acid
  参考文献：
  名称：

  Acetaldehyde stimulation of the growth of Saccharomyces cerevisiae in the presence of inhibitors found inlignocellulose-to-ethanol fermentations

  摘要：

  在含有抑制浓度的糠醛、乙酸盐和木质纤维素水解物中通常存在的其他化合物的发酵中加入少量乙醛，可显著减少酵母生长的滞后期，并促进乙醇的产生。在通过蒸汽/酸预处理生产的桦木水解物的发酵过程中加入乙醛（0.06 克/升），也能观察到类似的效果。在木质纤维素制乙醇发酵过程中，特别是在通过循环培养液产生高浓度抑制剂的发酵过程中，添加乙醛似乎有可能成为当前培养基解毒程序的低成本替代品（或辅助品）。工业微生物学与生物技术杂志》（2000 年）25 期，104-108 页。

  DOI：

  10.1038/sj.jim.7000031

文献信息

• Dalal; Nargund, Journal of the Indian Chemical Society, 1937, vol. 14, p. 406,409
  作者：Dalal、Nargund

  DOI：——

  日期：——
• Tectonics of Precambrian basement of the Tarim craton
  作者：Zhaojie Guo、Zhicheng Zhang、Chengzao Jia、Guoqi Wei

  DOI：10.1007/bf02882257

  日期：2001.3

  The Altyn Tagh Mountain is the main area where the Precambrian basements of Tarim craton are exposed. There are two ophiolitic belts in Altyn Tagh: one belt is exposed in the northern margin of Altyn Tagh whose formation age is about (829 +/- 60) Ma, the other is situated along the southern margin of Altyn Tagh and has a formation age of about (1449 +/- 270) Ma. This paper proposes a simple tectonic model for the Precambrian basement of Tarim craton established from ophiolites in Altyn Tagh area. The south Tarim block had amalgamated with Qaidam block during about 1400-1500 Ma along the present Altyn fault, while the south Tarim-Qaidam united block was still separated from the north Tarim block by an ocean. The united block of south Tarim and Qaidam collided with north Tarim block along the zone of high positive anomaly of central Tarim, Hongliugou and Lapeiquan in about 800 Ma. So since the Sinian (beginning at 800 Ma) there has been an integrated basement for Tarim craton.
• Murata; Satoh; Nohara, European Journal of Medicinal Chemistry, 1977, vol. 12, # 1, p. 17 - 20
  作者：Murata、Satoh、Nohara、et al.

  DOI：——

  日期：——
• MURATA TADAKAZU; SATOH HIROSHI; NOHARA AKIRA; UKAWA KIYOSHI; SUGIHARA HIR+, EUR. J. MED. CHEM., 1977, 12, NO 1, 17-20
  作者：MURATA TADAKAZU、 SATOH HIROSHI、 NOHARA AKIRA、 UKAWA KIYOSHI、 SUGIHARA HIR+

  DOI：——

  日期：——
• Acetaldehyde stimulation of the growth of Saccharomyces cerevisiae in the presence of inhibitors found inlignocellulose-to-ethanol fermentations
  作者：A R Barber、H Hansson、N B Pamment

  DOI：10.1038/sj.jim.7000031

  日期：2000.8.1

  The addition of small quantities of acetaldehyde to fermentations containing inhibitory concentrations of furfural, acetate and other compounds typically present in lignocellulosic hydrolyzates significantly reduced the lag phase of yeast growth and stimulated ethanol production. Similar effects were observed when acetaldehyde (0.06 g l−1) was added to fermentations of a birch wood hydrolyzate produced by steam/acid pretreatment. Acetaldehyde addition appears to have potential as a low-cost alternative (or adjunct) to current procedures for medium detoxification in lignocellulose-to-ethanol fermentations, particularly those in which high inhibitor concentrations are generated through recycling of the culture broth. Journal of Industrial Microbiology & Biotechnology (2000) 25, 104–108.

  在含有抑制浓度的糠醛、乙酸盐和木质纤维素水解物中通常存在的其他化合物的发酵中加入少量乙醛，可显著减少酵母生长的滞后期，并促进乙醇的产生。在通过蒸汽/酸预处理生产的桦木水解物的发酵过程中加入乙醛（0.06 克/升），也能观察到类似的效果。在木质纤维素制乙醇发酵过程中，特别是在通过循环培养液产生高浓度抑制剂的发酵过程中，添加乙醛似乎有可能成为当前培养基解毒程序的低成本替代品（或辅助品）。工业微生物学与生物技术杂志》（2000 年）25 期，104-108 页。