2-hydroxy-9,10-dihydrophenanthrene | 5329-90-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 菲及其衍生物
• 英文名称: 2-hydroxy-9,10-dihydrophenanthrene
• 英文别名: 9,10-Dihydro-[2]phenanthrol；2-Hydroxy-9.10-dihydro-phenanthren；9,10-Dihydrophenanthren-2-ol
• CAS: 5329-90-8
• 化学式: C₁₄H₁₂O
• 分子量: 196.249
• InChiKey: JCNDWTDGHRLQSX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  15
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

安全信息

• 海关编码：
  2906299090

反应信息

• 作为反应物：
  描述：

  2-hydroxy-9,10-dihydrophenanthrene 在 三氯化铝 、 potassium carbonate 、 硝基苯 作用下， 生成 1-(2-羟基-9,10-二氢-[3]菲基)-乙酮
  参考文献：
  名称：

  Texture analysis of IKONOS panchromatic data for Douglas-fir forest age class separability in British Columbia

  摘要：

  This Letter presents the results of textural separability tests obtained by first- and second-order texture methods on different aged Douglas-fir stands in IKONOS panchromatic imagery acquired 3 June 2000 over the Sooke River watershed in British Columbia. The effects of different measures and window sizes on the textural separability are discussed. Small windows sizes were not as effective in separating stands as larger windows sizes. Second-order (spatial co-occurrence homogeneity) texture values were the most effective in distinguishing between age classes. A first-order (variance) texture measure, though still useful, provided less separability.

  DOI：

  10.1080/01431160120769
• 作为产物：
  描述：

  2-乙酰氧基-9,10-二氢菲 在 盐酸 作用下， 以 甲醇 、 水 为溶剂， 反应 18.0h， 生成 2-hydroxy-9,10-dihydrophenanthrene
  参考文献：
  名称：

  扭转角变化的联苯硫醇自组装单层膜的多尺度电荷注入和输运性质

  摘要：

  本文描述了一系列联苯硫醇衍生物在金电极上自组装时在其分子骨架中具有不同扭转自由度的分子结构与功能的关系。化学吸附在Au上的这些联苯硫醇分子相对于表面法线表现出不同的倾斜角，并且具有不同的堆积密度。电荷通过联苯硫醇自组装单分子层（SAMs）传输时，有效单分子层厚度显示出特征衰减趋势。基于并行路径模型，隧道衰变因子β估计为0.27Å -1。结合有联苯硫醇SAM的Au（Au）源电极和漏电极涂覆的基于聚（3-己基噻吩）的薄膜晶体管的空穴迁移率显示出对注入势垒的依赖性，该注入势垒具有半导体中最高的分子轨道（HOMO）能级。讨论了SAMs在晶体管电极上的电阻率对阈值电压偏移的可能作用。对SAM的化学结构，电子特性和包装顺序的控制为调节有机电子设备中的电荷注入提供了一个多功能的平台。

  DOI：

  10.1002/chem.201201858

文献信息

• Mesomorphic compound, liquid crystal composition, liquid crystal device,
  申请人：Canon Kabushiki Kaisha

  公开号：US05213709A1

  公开（公告）日：1993-05-25

  A mesomorphic compound represented by the following formula (I): ##STR1## wherein R.sub.1 and R.sub.2 respectively denote an alkyl group having 1-16 carbon atoms optionally substituted; X.sub.1 and X.sub.3 respectively denote a single bond, --O--, ##STR2## X.sub.2 denotes a single bond, ##STR3## A.sub.1 denotes a single bond ##STR4## A.sub.3 denotes ##STR5## A.sub.2 denotes 9, 10-dihydro-2,7-phenanthrenediyl, 2,7-fluorenediyl or 2,7-fluorenonediyl; n is 0 or 1; and X.sub.4 and X.sub.5 respectively denote hydrogen, F, Cl, Br, --CH.sub.3, --CN or --CF.sub.3, with proviso that X.sub.1 is a single bond when A.sub.1 is a single bond.

  以下为化学式（I）所代表的一种介向化合物： ##STR1## 其中，R1和R2分别表示1-16个碳原子的烷基基团，可以选择性地被取代；X1和X3分别表示单键，--O--，##STR2##；X2表示单键，##STR3##；A1表示单键，##STR4##；A3表示##STR5##；A2表示9,10-二氢-2,7-菲基二基苯基、2,7-芴二基苯基或2,7-芴酮二基苯基；n为0或1；X4和X5分别表示氢、F、Cl、Br、--CH3、--CN或--CF3，但X1为单键时，A1为单键。
• Anti-androgen compounds
  申请人：ARCH DEVELOPMENT CORPORATION

  公开号：EP0363128A2

  公开（公告）日：1990-04-11

  Disclosed are novel classes of anti-androgens including dihydrophenanthrene derivatives, their method of synthesis and their use in treating disorders associated with excessive androgenic activities.

  所公开的是包括二氢菲衍生物在内的新型抗雄激素类别、其合成方法及其在治疗与雄激素活性过高有关的疾病中的用途。
• Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method
  申请人：CANON KABUSHIKI KAISHA

  公开号：EP0455219A1

  公开（公告）日：1991-11-06

  A mesomorphic compound represented by the following formula (I): wherein R1 and R2 respectively denote an alkyl group having 1 - 16 carbon atoms optionally substituted; X1 and X3 respectively denote a single bond, -0-, X2 denotes a single bond, A1 denotes a single bond A3 denotes A2 denotes 9, 10-dihydro-2,7-phenanthrenediyl, 2,7-fluorenediyl or 2,7-fluorenonediyl; n is 0 or 1; and X4 and X5 respectively denote hydrogen, F, Cl, Br, -CH3, -CN or -CF3, with proviso that X1 is a single bond when A1 is a single bond.

  由下式(I)表示的中间体化合物： X2 表示单键、 A1 表示单键 A3 表示 A2 表示 9，10-二氢-2，7-菲二基、2，7-芴二基或 2，7-芴酮二基；n 为 0 或 1；X4 和 X5 分别表示氢、F、Cl、Br、-CH3、-CN 或 -CF3，但当 A1 为单键时，X1 为单键。
• ——
  作者：M. Dellagreca、A. Fiorentino、P. Monaco、A. Pollio、L. Previtera、A. Zarrelli

  DOI：10.1023/a:1005463802388

  日期：——

  9,10-Dihydrophenanthrenes and phenanthrenes, mimics of natural compounds with strong antialgal activity, have been synthesized through cross-coupling of 1-(2-iodo-5-methoxy)-phenylethanol with variously substituted iodobenzenes. The synthetic compounds, bearing a hydroxyl or a methoxyl group at C-2 and a methyl in the C ring, were tested against the green alga Selenastrum capricornutum. All compounds, except 2-methoxy-7-methylphenanthrene, caused inhibition of algal growth by more than 70% at 10(-4) M, and many of them retained this strong activity at 10(-5) M.
• Studies in the Phenanthrene Series. XV. Observations on Substitution in 9,10-Dihydrophenanthrene: Tetracyclic Compounds Derived from It¹
  作者：Alfred Burger、Erich Mosettig

  DOI：10.1021/ja01286a042

  日期：1937.7