2-(3,5-Dimethyl-1-adamantyl)-ethanol-1 | 50847-70-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-(3,5-Dimethyl-1-adamantyl)-ethanol-1
• 英文别名: 3,5-Dimethyl-1-adamantaneethanol；2-(3,5-dimethyl-1-adamantyl)ethanol
• CAS: 50847-70-6
• 化学式: C₁₄H₂₄O
• 分子量: 208.344
• InChiKey: KHLNQUBFWFCMMK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

安全信息

• 海关编码：
  2906199090

反应信息

• 作为产物：
  描述：

  3,5-二甲基-1-金刚烷乙酸 在 lithium aluminium tetrahydride 作用下， 生成 2-(3,5-Dimethyl-1-adamantyl)-ethanol-1
  参考文献：
  名称：

  Landa; Burkhard; Vais, Collection of Czechoslovak Chemical Communications, 1973, vol. 38, # 10, p. 2947 - 2952

  摘要：

  DOI：

文献信息

• Method for Inhibition of Potential-Dependent Cation Channel
  申请人：Takatoku Hiroko

  公开号：US20130045177A1

  公开（公告）日：2013-02-21

  An excellent potential-dependent cation channel inhibitor or an excellent masking agent is provided. Disclosed is a method for inhibiting a potential-dependent cation channel or a method for masking olfaction, both of which include administering an adamantane derivate represented by the following formula (1) or a salt thereof [wherein R′ and R 2 are identical with or different from each other, and each represent a hydrogen atom or an alkyl group having 1 to 6 carbon atoms; and X represents —OH, —R 3 —OH (wherein R 3 represents an alkylene group having 1 to 6 carbon atoms), —NH 2 , —R 4 —NH 2 (wherein R 4 represents an alkylene group having 1 to 6 carbon atoms), —COOH, —R 5 —COOH (wherein R 5 represents an alkylene group having 1 to 6 carbon atoms), —CO-R 6 (wherein R 6 represents an alkyl group having 1 to 6 carbon atoms), —CO—R 7 —COO—R 8 (wherein R 7 represents an alkylene group having 1 to 6 carbon atoms, and R 8 represents an alkyl group having 1 to 6 carbon atoms), or —NHCO—R 9 (wherein R 9 represents an alkyl group having 1 to 6 carbon atoms)].
• US8481016B2
  申请人：——

  公开号：US8481016B2

  公开（公告）日：2013-07-09