2-(benzotriazol-1-yl)-2-carbazol-9-yl-N-phenylethanethioamide | 132724-60-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 2-(benzotriazol-1-yl)-2-carbazol-9-yl-N-phenylethanethioamide
• CAS: 132724-60-8
• 化学式: C₂₆H₁₉N₅S
• 分子量: 433.536
• InChiKey: WKQXHRZJIKMQBC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.1
• 重原子数：
  32
• 可旋转键数：
  4
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.04
• 拓扑面积：
  79.8
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-(benzotriazol-1-yl)-2-carbazol-9-yl-N-phenylethanethioamide 、 2,4-二硝基苯肼 在 高氯酸 、 硫酸 作用下， 生成 2-[(2,4-Dinitro-phenyl)-hydrazono]-N-phenyl-thioacetamide
  参考文献：
  名称：

  1-(Carbazol-9-ylmethyl)benzotriazole anion: a formyl anion equivalent

  摘要：

  The title anion, readily available as its lithium derivative, smoothly reacts with a wide range of electrophiles to give well-characterized products which are easily hydrolyzed to the corresponding aldehydes in high overall yields. The method is compared with currently available routes.

  DOI：

  10.1021/jo00006a034
• 作为产物：
  描述：

  1-(chloromethyl)benzotriazole 在 sodium hydroxide 、 正丁基锂 作用下， 以 二甲基亚砜 为溶剂， 反应 22.0h， 生成 2-(benzotriazol-1-yl)-2-carbazol-9-yl-N-phenylethanethioamide
  参考文献：
  名称：

  1-(Carbazol-9-ylmethyl)benzotriazole anion: a formyl anion equivalent

  摘要：

  The title anion, readily available as its lithium derivative, smoothly reacts with a wide range of electrophiles to give well-characterized products which are easily hydrolyzed to the corresponding aldehydes in high overall yields. The method is compared with currently available routes.

  DOI：

  10.1021/jo00006a034

文献信息

• KATRITZKY, ALAN R.;YANG, ZHIJUN;LAM, JAMSHED N., J. ORG. CHEM. , 56,(1991) N, C. 2143-2147
  作者：KATRITZKY, ALAN R.、YANG, ZHIJUN、LAM, JAMSHED N.

  DOI：——

  日期：——
• 1-(Carbazol-9-ylmethyl)benzotriazole anion: a formyl anion equivalent
  作者：Alan R. Katritzky、Zhijun Yang、Jamshed N. Lam

  DOI：10.1021/jo00006a034

  日期：1991.3

  The title anion, readily available as its lithium derivative, smoothly reacts with a wide range of electrophiles to give well-characterized products which are easily hydrolyzed to the corresponding aldehydes in high overall yields. The method is compared with currently available routes.