1-[2-羟基-4-(甲氧基甲氧基)苯基]-3-苯基丙烷-1,3-二酮 | 130483-43-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 直链 1,3-二芳基丙烷
• 中文名称: 1-[2-羟基-4-(甲氧基甲氧基)苯基]-3-苯基丙烷-1,3-二酮
• 英文名称: 1-<2-hydroxy-4-(methoxymethoxy)phenyl>-3-phenylpropane-1,3-dione
• 英文别名: 1-[2-Hydroxy-4-(methoxymethoxy)phenyl]-3-phenylpropane-1,3-dione
• CAS: 130483-43-1
• 化学式: C₁₇H₁₆O₅
• 分子量: 300.311
• InChiKey: PZXJQFFXJFXQCP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  22
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  72.8
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  1-[2-羟基-4-(甲氧基甲氧基)苯基]-3-苯基丙烷-1,3-二酮 在 Amberlyst 15 resin 作用下， 以 异丙醇 为溶剂， 反应 6.5h， 以93%的产率得到7-羟基黄酮
  参考文献：
  名称：

  Patonay, Tamas; Molnar, Denes; Muranyi, Zoltan, Bulletin de la Societe Chimique de France, 1995, vol. 132, # 2, p. 233 - 242

  摘要：

  DOI：
• 作为产物：
  描述：

  苯甲酸乙酯 、 1-[2-羟基-4-(甲氧基甲氧基)苯基]乙酮 在 sodium hydride 作用下， 以 四氢呋喃 为溶剂， 反应 1.5h， 以42%的产率得到1-[2-羟基-4-(甲氧基甲氧基)苯基]-3-苯基丙烷-1,3-二酮
  参考文献：
  名称：

  Patonay, Tamas; Molnar, Denes; Muranyi, Zoltan, Bulletin de la Societe Chimique de France, 1995, vol. 132, # 2, p. 233 - 242

  摘要：

  DOI：

文献信息

• Cobalt schiff base complex promoted retro-claisen reaction of 1-(2-hydroxyphenyl)-3-phenyl-1,3-propanediones and flavone formation
  作者：Akira Nishinaga、Kazushige Maruyama、Hiroyuki Ando、Ryoji Sato、Takahiro Mashino、Inada Akira、Nakanishi Tsutomu

  DOI：10.1016/s0040-4039(00)94724-5

  日期：1990.1

  Co(salpr) promotes the conversion of 1-(2-hydroxyphenyl)-3-phenyl-1,3-propanediones to retro-Claisen reaction products and flavones in methanol under oxygen. Base catalysis by Co(salpr)(OH) produced in situ is responsible for the reaction.

  Co（salpr）在氧气下在甲醇中促进1-（2-羟苯基）-3-苯基-1,3-丙二酮向逆Claisen反应产物和黄酮的转化。原位产生的Co（salpr）（OH）的碱催化作用是该反应的原因。
• NISHINAGA, AKIRA;MARUYAMA, KAZUSHIGE;ANDO, HIROYUKI;SATO, RYOJI;MASHINO, +, TETRAHEDRON LETT., 31,(1990) N2, C. 3171-3174
  作者：NISHINAGA, AKIRA、MARUYAMA, KAZUSHIGE、ANDO, HIROYUKI、SATO, RYOJI、MASHINO, +

  DOI：——

  日期：——
• LUMINESCENT DIKETONATE POLYMERS
  申请人：Fraser Cassandra L.

  公开号：US20090137057A1

  公开（公告）日：2009-05-28

  The present invention provides in one aspect polymeric luminescent dye compounds having fluorescent properties, phosphorescent properties, or both fluorescent and phosphorescent properties.
• COMPOSITIONS AND METHODS FOR MAKING AND USING OXYGEN SENSING NANOFIBERS AND SCAFFOLDS
  申请人：University of Virginia Patent Foundation

  公开号：US20160041177A1

  公开（公告）日：2016-02-11

  To address the need for scaffold-based oxygen concentration monitoring, a single-component, self-referenced oxygen sensor was made into nanofibers. Electrospinning process parameters were tuned to produce a biomaterial scaffold with specific morphological features. The ratio of an oxygen sensitive phosphorescence signal to an oxygen insensitive fluorescence signal was calculated at each image pixel to determine an oxygenation value. A single component boron dye-polymer conjugate was chosen for additional investigation due to improved resistance to degradation in aqueous media compared to a dye polymer blend. Standardization curves show that in fully supplemented media, the fibers are responsive to dissolved oxygen concentrations less than 15 parts per million. Spatial and temporal ratiometric gradients were observed in vitro radiating outward from the center of a dense adherent cell grouping. Sensor activation in ischemia and cell transplant models in vivo show oxygenation decreases on the scale of minutes.
• US7955861B2
  申请人：——

  公开号：US7955861B2

  公开（公告）日：2011-06-07