iso-vinyl-β-ionol | 242485-41-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: iso-vinyl-β-ionol
• 英文别名: (1E)-3-methyl-1-(2,3,3-trimethylcyclohexen-1-yl)penta-1,4-dien-3-ol
• CAS: 242485-41-2
• 化学式: C₁₅H₂₄O
• 分子量: 220.355
• InChiKey: QTGFVUIDSAOOBE-PKNBQFBNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  iso-vinyl-β-ionol 在 sodium ethanolate 作用下， 以 甲醇 、 乙醇 为溶剂， 反应 49.25h， 生成 (4Z)-iso-retinyl acetate
  参考文献：
  名称：

  New Retinoid Analogs from δ-Pyronene, a Natural Synthon

  摘要：

  delta-Pyronene (1), a readily available terpenic synthon, is an excellent raw material for the preparation of numerous terpenic intermediates. Original retinoid analogs such as "iso"-retinyl acetate (5), "iso"-retinal (6) and ethyl "iso"-retinoate (7), in which the cyclogeranyl moiety is functionalized in an unusual position, were prepared from delta-pyronene.

  DOI：

  10.1002/(sici)1099-0690(199906)1999:6<1489::aid-ejoc1489>3.0.co;2-1
• 作为产物：
  描述：

  4-(Benzenesulfinyl)-3-methyl-5-(2,3,3-trimethylcyclohexen-1-yl)pent-1-en-3-ol 在 potassium carbonate 作用下， 以 甲苯 为溶剂， 反应 72.0h， 以83%的产率得到iso-vinyl-β-ionol
  参考文献：
  名称：

  New Retinoid Analogs from δ-Pyronene, a Natural Synthon

  摘要：

  delta-Pyronene (1), a readily available terpenic synthon, is an excellent raw material for the preparation of numerous terpenic intermediates. Original retinoid analogs such as "iso"-retinyl acetate (5), "iso"-retinal (6) and ethyl "iso"-retinoate (7), in which the cyclogeranyl moiety is functionalized in an unusual position, were prepared from delta-pyronene.

  DOI：

  10.1002/(sici)1099-0690(199906)1999:6<1489::aid-ejoc1489>3.0.co;2-1

文献信息

• New Retinoid Analogs from δ-Pyronene, a Natural Synthon
  作者：Frédéric Lambertin、Martin Wende、Marie Jeanne Quirin、Martine Taran、Bernard Delmond

  DOI：10.1002/(sici)1099-0690(199906)1999:6<1489::aid-ejoc1489>3.0.co;2-1

  日期：1999.6

  delta-Pyronene (1), a readily available terpenic synthon, is an excellent raw material for the preparation of numerous terpenic intermediates. Original retinoid analogs such as "iso"-retinyl acetate (5), "iso"-retinal (6) and ethyl "iso"-retinoate (7), in which the cyclogeranyl moiety is functionalized in an unusual position, were prepared from delta-pyronene.