(2R,3S,4R,5R,6R)-2-[(E)-hex-1-enyl]-3,4,5-tris(phenylmethoxy)-6-(phenylmethoxymethyl)oxane | 135067-80-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2R,3S,4R,5R,6R)-2-[(E)-hex-1-enyl]-3,4,5-tris(phenylmethoxy)-6-(phenylmethoxymethyl)oxane
• CAS: 135067-80-0；135212-03-2
• 化学式: C₄₀H₄₆O₅
• 分子量: 606.802
• InChiKey: USTPPMGUEXTMJV-WKYIQPNOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.47
• 重原子数：
  45.0
• 可旋转键数：
  17.0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.35
• 拓扑面积：
  46.15
• 氢给体数：
  0.0
• 氢受体数：
  5.0

反应信息

• 作为反应物：
  描述：

  三甲基乙酰氯 、 (2R,3S,4R,5R,6R)-2-[(E)-hex-1-enyl]-3,4,5-tris(phenylmethoxy)-6-(phenylmethoxymethyl)oxane 在 吡啶 、 氨 、 lithium 作用下， 生成 2,2-Dimethyl-propionic acid (2R,3R,4R,5S,6R)-3,5-bis-(2,2-dimethyl-propionyloxy)-2-(2,2-dimethyl-propionyloxymethyl)-6-((E)-hex-1-enyl)-tetrahydro-pyran-4-yl ester
  参考文献：
  名称：

  Acid-induced anomerization of 1-deoxy-1-C-alkenylglycopyranose derivatives

  摘要：

  Precise conditions permitting equilibration between alpha- and beta-anomers of certain 1-deoxy-1-C-alkenylglycopyranose compounds have been established. It is shown that the beta-configuration is favored over the alpha- by a ratio of more than 9:1 at equilibrium. Under these conditions stereoconvergent access to the beta-alkenylglycopyranose derivatives may be achieved in preparatively useful yields.

  DOI：

  10.1016/s0040-4039(00)79679-1
• 作为产物：
  描述：

  二异丁基[(E)-1-己烯基]铝 、 2,3,4,6-四-O-苄基-D-吡喃葡萄糖酰氟 以56%的产率得到(2R,3S,4R,5R,6R)-2-[(E)-hex-1-enyl]-3,4,5-tris(phenylmethoxy)-6-(phenylmethoxymethyl)oxane
  参考文献：
  名称：

  Acid-induced anomerization of 1-deoxy-1-C-alkenylglycopyranose derivatives

  摘要：

  Precise conditions permitting equilibration between alpha- and beta-anomers of certain 1-deoxy-1-C-alkenylglycopyranose compounds have been established. It is shown that the beta-configuration is favored over the alpha- by a ratio of more than 9:1 at equilibrium. Under these conditions stereoconvergent access to the beta-alkenylglycopyranose derivatives may be achieved in preparatively useful yields.

  DOI：

  10.1016/s0040-4039(00)79679-1