methyl (E)-11-tetradecenoate | 119136-11-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: methyl (E)-11-tetradecenoate
• 英文别名: Methyl 11(E)-tetradecenoate；methyl 11-tetradecenoate；Methyl E-11-tetradecenoate；methyl (E)-tetradec-11-enoate
• CAS: 119136-11-7
• 化学式: C₁₅H₂₈O₂
• 分子量: 240.386
• InChiKey: BDWJRABOFNWETH-SNAWJCMRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  17
• 可旋转键数：
  12
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  methyl (E)-11-tetradecenoate 在 lithium aluminium tetrahydride 作用下， 以 四氢呋喃 、 吡啶 为溶剂， 反应 28.0h， 生成 醋酸(E)-11-十四烯酯
  参考文献：
  名称：

  Vinczer, Peter; Juvancz, Zoltan; Novak, Lajos, Acta Chimica Hungarica, 1988, vol. 125, # 6, p. 797 - 820

  摘要：

  DOI：
• 作为产物：
  描述：

  methyl 11-hydroxyundecanoate 在 正丁基锂 、 sodium acetate 、 pyridinium chlorochromate 作用下， 以 二氯甲烷 、 甲苯 为溶剂， 反应 26.0h， 生成 methyl (E)-11-tetradecenoate
  参考文献：
  名称：

  Vinczer, Peter; Juvancz, Zoltan; Novak, Lajos, Acta Chimica Hungarica, 1988, vol. 125, # 6, p. 797 - 820

  摘要：

  DOI：

文献信息

• Metathesis syntheses of pheromones or their components
  申请人：——

  公开号：US20020022741A1

  公开（公告）日：2002-02-21

  The present invention relates to metathesis syntheses for insect sex-attractant pheromones or their components, such as E-5-decenyl acetate, the major component of the Peach Twig Borer pheromone; (5R, 6S)-6-acetoxy-5-hexadecanolide, the mosquito oviposition attractant pheromone; E9, Z11-hexadecadienal, the pecan nut casebearer moth pheromone; 9-tetradecenyl formate, an analog of the Diamondback Moth (DBM) pheromone; 11-tetradecenyl acetate, the Omnivorous Leafroller (OLR) pheromone; E-4-tridecenyl acetate, the major component of the Tomato Pinworm (TPW) pheromone; E,E-8,10-dodecadienol, the Codling Moth (CM) pheromone. The syntheses preferably employ a Class I-IV metathesis catalyst, entail few reaction steps, use generally commercially available starting materials, and have relatively short process times. These syntheses produce good yields without the need for expensive or sophisticated equipment. The invention also provides an inexpensive route for producing omega-haloalkenols by cross-metathesizing alpha-omega-diacetoxy alkenes and alpha-omega-dihalides to yield omega-haloalkenols, which are easily converted into omega-haloalkanols under traditional hydrogenation methods.

  本发明涉及对昆虫性诱素或其组分进行交换合成，如E-5-癸烯醇醋酸酯，桃枝蠕蛾性信息素的主要成分；（5R, 6S）-6-乙酰氧基-5-十六醇内酯，蚊子产卵引诱素；E9, Z11-癸二烯醛，山核桃果蛾性信息素；9-十四烯酸甲酯，菜青虫性信息素的类似物；11-十四烯醇醋酸酯，杂食卷叶蛾性信息素；E-4-十三烯醇醋酸酯，番茄针孔螟性信息素的主要成分；E,E-8,10-十二二烯醇，苹果蛾性信息素。这些合成通常采用I-IV类交换催化剂，步骤较少，使用通常易得的起始物质，并具有相对较短的工艺时间。这些合成产量良好，无需昂贵或复杂的设备。该发明还提供了通过交叉交换α-Ω-二乙酰基烯烃和α-Ω-二卤代烃来产生Ω-卤代烯醇的廉价途径，后者可以在传统的氢化方法下轻松转化为Ω-卤代烷醇。
• PRODUCTION PROCESS OF GENDER-SPECIFIC SERUM AND BIOMARKER USING THE SERUM
  申请人：Industry-Academic Cooperation Foundation Yeungnam University

  公开号：EP2418484A2

  公开（公告）日：2012-02-15

  The present invention relates to a production process of a gender-specific serum and a biomarker using the serum. More specifically, the present invention uses a fatty acid that exhibits a specific expression pattern in a gender-specific serum as a biomarker not only for diagnosis of obesity or a disease related to obesity, but also for diagnosis of meat quality since the fatty acid promotes differentiation of muscle derived stem cells into adipose cells. In addition, the present invention can establish a research system studying the effects of steroid hormones on the cell culture by using sera separated from blood that is collected from individual mammal carcasses being disposed, and provide important clues for discovering a gene associated with the synthesis of steroid hormone and for developing treatments for human diseases. Further, the present invention may contribute to increased profits derived from producing high quality sera, a reduced cost with treatment for carcass wastes, and promotion of the eco-industry for reducing environmental hormones.

  本发明涉及一种性别特异性血清的生产工艺和一种使用该血清的生物标记物。更具体地说，本发明使用一种在性别特异性血清中表现出特定表达模式的脂肪酸作为生物标志物，不仅可用于诊断肥胖或与肥胖有关的疾病，还可用于诊断肉质，因为这种脂肪酸可促进肌肉衍生干细胞分化为脂肪细胞。此外，本发明还可以建立一个研究系统，利用从被处理的哺乳动物尸体上采集的血液中分离出来的血清，研究类固醇激素对细胞培养的影响，并为发现与类固醇激素合成有关的基因和开发人类疾病的治疗方法提供重要线索。此外，本发明还有助于提高生产高质量血清的利润，降低处理胴体废物的成本，促进减少环境荷尔蒙的生态产业。
• Vinczer, Peter; Novak, Lajos; Szantay, Csaba, Organic Preparations and Procedures International, 1991, vol. 23, # 4, p. 443 - 447
  作者：Vinczer, Peter、Novak, Lajos、Szantay, Csaba

  DOI：——

  日期：——
• Singh, Krishna Nand; Singh, Manorama; Misra, Ram Achal, Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1991, vol. 30, # 9, p. 867 - 868
  作者：Singh, Krishna Nand、Singh, Manorama、Misra, Ram Achal

  DOI：——

  日期：——
• VINCZER, P.;JUVANCZ, Z.;NOVAK, L.;SZANTAY, CS., IZV. AN EHSSR. XIMIYA, 37,(1988) N 3, S. 215-219
  作者：VINCZER, P.、JUVANCZ, Z.、NOVAK, L.、SZANTAY, CS.

  DOI：——

  日期：——