1,3-diphenylpropan-1-one | 108475-88-3

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 直链 1,3-二芳基丙烷
• 英文名称: 1,3-diphenylpropan-1-one
• 英文别名: 2,3-dihydroxy-1,3-diphenyl-propan-1-one；2,3-Dihydroxy-1,3-diphenyl-propan-1-on；2,3-Dihydroxy-1,3-diphenyl-1-propanone；2,3-dihydroxy-1,3-diphenylpropan-1-one
• CAS: 108475-88-3
• 化学式: C₁₅H₁₄O₃
• 分子量: 242.274
• InChiKey: QOFVVEZPQRISRL-UHFFFAOYSA-N

物化性质

• 熔点：
  87-89 °C
• 沸点：
  455.6±45.0 °C(Predicted)
• 密度：
  1.246±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  57.5
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  1,3-diphenylpropan-1-one 生成 (2RS,3RS)-2,3-bis-benzoyloxy-1,3-diphenyl-propan-1-one
  参考文献：
  名称：

  Reichel; Doering, Justus Liebigs Annalen der Chemie, 1957, vol. 606, p. 137,145

  摘要：

  DOI：
• 作为产物：
  描述：

  苯亚甲基苯乙酮 在 potassium bromate 、 四氧化锇 、 硫酸 、 mercury(II) diacetate 、 溶剂黄146 作用下， 生成 1,3-diphenylpropan-1-one
  参考文献：
  名称：

  Veeraiah; Sondu, Indian Journal of Chemistry, Section A: Inorganic, Physical, Theoretical and Analytical, 1996, vol. 35, # 12, p. 1073 - 1078

  摘要：

  DOI：

文献信息

• Padmaja, S.; Rao, K. Nageswar; Rao, M. Prasad, Indian Journal of Chemistry, Section A: Inorganic, Physical, Theoretical and Analytical, 1995, vol. 34, # 5, p. 351 - 354
  作者：Padmaja, S.、Rao, K. Nageswar、Rao, M. Prasad、Sethuram, B.

  DOI：——

  日期：——
• Molecular characterization of NbEH1 and NbEH2, two epoxide hydrolases from Nicotiana benthamiana
  作者：Fong-Chin Huang、Wilfried Schwab

  DOI：10.1016/j.phytochem.2013.02.020

  日期：2013.6

  Plant epoxide hydrolases (EH) form two major clades, named EH1 and EH2. To gain a better understanding of the biochemical roles of the two classes, NbEH1.1 and NbEH2.1 were isolated from Nicotiana benthamiana and StEH from potato and heterologously expressed in Escherichia coli. The purified recombinant proteins were assayed with a variety of substrates. NbEH1.1 only accepted some aromatic epoxides, and displayed the highest enzyme activity towards phenyl glycidyl ether. In contrast, NbEH2.1 displayed a broad substrate range and similar substrate specificity as StEH. The latter enzymes showed activity towards all fatty acid epoxides examined. The activity (V-max) of NbEH1.1 towards phenyl glycidyl ether was 10 times higher than that of NbEH2.1. On the contrary, NbEH2.1 converted cis-9,10-epoxystearic acid With V-max of 3.83 mu mol min mg(-1) but NbEH1.1 could not hydrolyze cis-9,10-epoxystearic acid. Expression analysis revealed that NbEH1.1 is induced by infection with tobacco mosaic virus (TMV) and wounding, whereas NbEH2.1 is present at a relatively constant level, not influenced by treatment with TMV and wounding. NbEH1.1 transcripts were present predominantly in roots, whereas NbEH2.1 mRNAs were detected primarily in leaves and stems. Overall, these two types of tobacco EH enzymes are distinguished not only by their gene expression, but also by different substrate specificities. EH1 seems not to participate in cutin biosynthesis and it may play a role in generating signals for activation of certain defence and stress responses in tobacco. However, members of the EH2 group hydrate fatty acid epoxides and may be involved in cutin monomer production in plants. (C) 2013 Elsevier Ltd. All rights reserved.
• Syntheses of Zinc Complexes with Multidentate Nitrogen Ligands: New Catalysts for Aldol Reactions
  作者：Tamis Darbre、Christian Dubs、Eduard Rusanov、Helen Stoeckli-Evans

  DOI：10.1002/1099-0682(200212)2002:12<3284::aid-ejic3284>3.0.co;2-6

  日期：2002.12
• CLERICI, ANGELO;PORTA, OMBRETTA, J. ORG. CHEM., 54,(1989) N6, C. 3872-3878
  作者：CLERICI, ANGELO、PORTA, OMBRETTA

  DOI：——

  日期：——