2-Hydroxy-6-methoxycyclohexanon | 137934-98-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-Hydroxy-6-methoxycyclohexanon
• 英文别名: 2-Hydroxy-6-methoxycyclohexan-1-one
• CAS: 137934-98-6
• 化学式: C₇H₁₂O₃
• 分子量: 144.17
• InChiKey: BFDYXWBYUWUSQJ-UHFFFAOYSA-N

物化性质

• 沸点：
  254.4±40.0 °C(Predicted)
• 密度：
  1.12±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  3-methoxy-1,2-cyclohexanediol 在 二甲基二环氧乙烷 作用下， 以 丙酮 为溶剂， 反应 48.0h， 生成 2-羟基-3-甲氧基环己酮 、 2-Hydroxy-6-methoxycyclohexanon
  参考文献：
  名称：

  Regioselective oxidation of azidodiols, bromodiols and triol derivatives by dimethyldioxirane

  摘要：

  Azidodiols, bromodiols and triol derivatives were regioselectively monooxidised to the corresponding ketols using dimethyldioxirane. This regioselectivity is essentially determined by dipolar functionalities close to the potential reactive carbinol. These results make the reactivity of polyols with dimethyldioxirane highly predictable. (C) 1998 Published by Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(98)00885-0

文献信息

• Habermehl, Gerhard G.; Wippermann, Irene, Zeitschrift fur Naturforschung, B: Chemical Sciences, 1991, vol. 46, # 10, p. 1421 - 1424
  作者：Habermehl, Gerhard G.、Wippermann, Irene

  DOI：——

  日期：——
• Regioselective oxidation of azidodiols, bromodiols and triol derivatives by dimethyldioxirane
  作者：Paolo Bovicelli、Danilo Truppa、Anna Sanetti、Roberta Bernini、Paolo Lupattelli

  DOI：10.1016/s0040-4020(98)00885-0

  日期：1998.11

  Azidodiols, bromodiols and triol derivatives were regioselectively monooxidised to the corresponding ketols using dimethyldioxirane. This regioselectivity is essentially determined by dipolar functionalities close to the potential reactive carbinol. These results make the reactivity of polyols with dimethyldioxirane highly predictable. (C) 1998 Published by Elsevier Science Ltd. All rights reserved.