7,8,3',4'-tetrahydroxy-3,5-dimethoxyflavone

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: 7,8,3',4'-tetrahydroxy-3,5-dimethoxyflavone
• 英文别名: gossypetin-3,5-dimethyl ether；7,8,3',4'-tetrahydroxyflavone-3,5,-dimethyl ether；3,5-di-O-methyl gossypetin；7,8,3',4'-Trihydroxy-3,5-dimethoxyflavone；2-(3,4-dihydroxyphenyl)-7,8-dihydroxy-3,5-dimethoxychromen-4-one
• 化学式: C₁₇H₁₄O₈
• 分子量: 346.293
• InChiKey: KNEPLXVAXBQPGZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  25
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  126
• 氢给体数：
  4
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  7,8,3',4'-tetrahydroxy-3,5-dimethoxyflavone 在 氢溴酸 作用下， 反应 0.5h， 以5 mg的产率得到棉花素
  参考文献：
  名称：

  Polyoxygenated flavonoids from Eugenia edulis

  摘要：

  Leaves of Eugenia edulis contain the new polyoxygenated flavonoid derivatives, gossypetin-3,8-dimethyl ether-5-O-beta-glucoside; gossypetin-3,5-dimethyl ether, and myricetin-3,5,3'-trimethyl ether. In addition, ten known polyphenolics were also isolated and identified. All structures were established on the basis of chemical and spectral evidence, including ESI-MS and C-13 NMR. (C) 2003 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/s0031-9422(03)00437-0

文献信息

• Polyoxygenated flavonoids from Eugenia edulis
  作者：Sahar A.M. Hussein、Amani N.M. Hashem、Mohammed A. Seliem、Ulrike Lindequist、Mahmoud A.M. Nawwar

  DOI：10.1016/s0031-9422(03)00437-0

  日期：2003.10

  Leaves of Eugenia edulis contain the new polyoxygenated flavonoid derivatives, gossypetin-3,8-dimethyl ether-5-O-beta-glucoside; gossypetin-3,5-dimethyl ether, and myricetin-3,5,3'-trimethyl ether. In addition, ten known polyphenolics were also isolated and identified. All structures were established on the basis of chemical and spectral evidence, including ESI-MS and C-13 NMR. (C) 2003 Elsevier Ltd. All rights reserved.

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