1,3-二苯基丙烷-1,3-二胺 | 19293-52-8

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 直链 1,3-二芳基丙烷
• 中文名称: 1,3-二苯基丙烷-1,3-二胺
• 英文名称: 1,3-diphenyl-propanediyldiamine
• 英文别名: 1,3-Diphenyl-propandiyldiamin；meso-1.3-Diphenyl-1.3-propandiamin；1,3-Diamino-3,3-diphenylpropan；1,3-Diphenyl-1,3-diaminopropan；1.3-Diphenyl-propan-1.3-diamin；1,3-Diphenyl-1,3-propandiamin；1,3-Diphenylpropane-1,3-diamine
• CAS: 19293-52-8
• 化学式: C₁₅H₁₈N₂
• 分子量: 226.321
• InChiKey: ILDQIFPNBGCLRH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  52
• 氢给体数：
  2
• 氢受体数：
  2

安全信息

• 海关编码：
  2921590090

反应信息

• 作为反应物：
  描述：

  1,3-二苯基丙烷-1,3-二胺 在 吡啶 、 碘 、 potassium carbonate 、 sodium hydroxide 作用下， 以 二氯甲烷 、 二甲基亚砜 、 叔丁醇 为溶剂， 反应 4.0h， 生成 嘧啶,2,4,6-三苯基-
  参考文献：
  名称：

  Efficient and Benign One-Pot Conversion of N-Tosyl-1,4,5,6-tetrahydropyrimidines to Pyrimidines via Tandem β-Elimination and Aromatization

  摘要：

  An efficient, mild, benign, and practical method for one-pot conversion of N-tosyl-1,4,5,6-tetrahydropyrimidines into pyrimidines is discussed in detail. In this method, N-tosyl-1,4,5,6-tetrahydropyrimidines are first prepared via N-tosylation of tetrahydropyrimidines with TsCl and then treated with 1.5 equivalents of NaOH in dimethylsulfoxide (DMSO) under air at 60 degrees C to afford corresponding pyrimidines in 70-95% yields via cascade -elimination and aromatization. [Supplementary materials are available for this article. Go to the publisher's online edition of Synthetic Communications (R) for the following free supplemental resources: Full experimental and spectral details.]

  DOI：

  10.1080/00397911.2013.764433
• 作为产物：
  描述：

  1,3-二苯基丙烷-1,3-二肟 在 1,4-二氧六环 、 镍 作用下， 生成 1,3-二苯基丙烷-1,3-二胺
  参考文献：
  名称：

  Samne, Annales de Chimie (Cachan, France), 1957, vol. <13>2, p. 629,643

  摘要：

  DOI：

文献信息

• HYDROGENATION OF ESTERS OR CARBONYL GROUPS WITH PHOSPHINO-OXIDE BASED RUTHENIUM COMPLEXES
  申请人：Saudan Lionel

  公开号：US20110190523A1

  公开（公告）日：2011-08-04

  The present invention relates to the field of catalytic hydrogenation and, more particularly, to the use of specific ruthenium catalysts or pre-catalysts in hydrogenation processes for the reduction of ketones, aldehydes, esters or lactones into their corresponding alcohols or diols respectively. The preferred catalysts are ruthenium complexes comprising a ligand of the type (N—N) type and a ligand of the type (P—PO).

  本发明涉及催化加氢领域，更具体地涉及在加氢过程中使用特定的钌催化剂或前驱体，用于将酮、醛、酯或内酯还原为相应的醇或二醇。首选催化剂是包含(N—N)型配体和(P—PO)型配体的钌配合物。
• SELECTIVE HYDROGENATION OF ALDEHYDE WITH RU/BIDENTATE LIGANDS COMPLEXES
  申请人：FIRMENICH SA

  公开号：US20140243526A1

  公开（公告）日：2014-08-28

  The present invention relates to processes for the reduction by hydrogenation, using molecular H 2 , of a C 5 -C 20 substrate containing one or two aldehydes functional groups into the corresponding alcohol or diol, characterized in that said process is carried out in the presence of —at least one catalyst or pre-catalyst in the form of a ruthenium complex having a coordination sphere of the N 2 P 2 O 2 , wherein the coordinating atoms N 2 are provided by a first bidentate ligand, the coordinating atoms P 2 are provided by a second bidentate ligand and the coordinating atoms O 2 are provided by two non-linear carboxylate ligands; and —optionally of an acidic additive.

  本发明涉及利用分子H2对含有一个或两个醛基官能团的C5-C20底物进行加氢还原的过程，将其转化为相应的醇或二醇，其特征在于所述过程在以下条件下进行：—至少一种催化剂或前驱体存在，其形式为具有N2P2O2配位球的钌配合物，其中配位原子N2由第一双齿配体提供，配位原子P2由第二双齿配体提供，配位原子O2由两个非线性羧酸盐配体提供；和—可选地加入酸性添加剂。
• METHOD FOR PRODUCING ENDO-9-AZABICYCLO[3.3.1]NONAN-3-OL DERIVATIVE
  申请人：NIPPON SODA CO., LTD.

  公开号：US20160200726A1

  公开（公告）日：2016-07-14

  A 9-azabicyclo[3.3.1]nonan-3-one derivative is reacted with a hydrogen in the presence of a catalyst composed of a ruthenium complex to obtain, at a low cost, an endo-9-azabicyclo[3.3.1]nonan-3-ol derivative useful as a production intermediate for agrochemical agents or medicines.

  在9-氮杂双环[3.3.1]壬烷-3-酮衍生物在钌配合物催化剂存在下与氢发生反应，从而以较低成本获得一种有用的内环9-氮杂双环[3.3.1]壬烷-3-醇衍生物，可用作农药或药物的生产中间体。
• Substituted diphenyloxazoles, the synthesis thereof, and the use thereof as fluorescence probes
  申请人：3-Dimensional Pharmaceuticals, Inc.

  公开号：US20030105111A1

  公开（公告）日：2003-06-05

  The present invention is directed to a compound of Formula I: 1 wherein A, R 1 , and R 2 are defined herein. The present invention is also directed to compositions comprising compounds of Formula I, methods of using compounds of Formula I, and methods of making compounds of Formula I.

  本发明涉及一种具有以下结构的化合物：其中A、R1和R2在此处被定义。本发明还涉及包含Formula I化合物的组合物、使用Formula I化合物的方法以及制备Formula I化合物的方法。
• Curable epoxide resin mixtures containing diaminopropanes
  申请人：Ciba-Geigy Corporation

  公开号：US04193905A1

  公开（公告）日：1980-03-18

  Curable mixtures comprising a polyepoxide compound having on average more than one epoxide group per molecule and a 1,3-diaminopropane of the formula ##STR1## wherein R.sup.1 denotes hydrogen and R.sup.1, R.sup.2, R.sup.3 and R.sup.4 each denote an alkyl having 1 to 12 C atoms, a phenyl or a heterocyclic 5-membered or 6-membered radical, or wherein R.sup.1 and R.sup.2 together with the C atom in the .alpha.-position of the propylenediamine from a substituted or unsubstituted aliphatic 5-membered or 6-membered ring having at most 12 C atoms and R.sup.3 and R.sup.4 together with the two C atoms in the .alpha.-position and the .beta.-position of the propylenediamine form a substituted or unsubstituted aliphatic or N-heterocyclic 5-membered or 6-membered ring having at most 12 C atoms, said mixtures containing 0.5 to 1.5 equivalents of active hydrogen atoms, bonded to nitrogen, in the 1,3-diaminopropane per 1 equivalent of epoxide groups in the epoxide compound. The curable mixtures are valuable casting resins and adhesives and are suitable for the preparation of storable B-stage resins.

  可治疗混合物包括平均每分子具有多于一个环氧基团的聚环氧化合物和式为##STR1##的1,3-二氨基丙烷，其中R.sup.1表示氢，R.sup.1，R.sup.2，R.sup.3和R.sup.4各自表示具有1到12个碳原子的烷基，苯基或杂环5元或6元基，或者其中R.sup.1和R.sup.2与丙二胺的α-位碳原子形成具有最多12个碳原子的取代或未取代脂肪族5元或6元环，R.sup.3和R.sup.4与丙二胺的α-位和β-位碳原子形成具有最多12个碳原子的取代或未取代脂肪族或N-杂环5元或6元环，所述混合物含有每个环氧化合物中的1当量环氧基团对应的0.5到1.5当量与氮相键合的活性氢原子的1,3-二氨基丙烷。这些可固化混合物是有价值的铸造树脂和粘合剂，适用于制备可储存的B级树脂。

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