丙烷-1,1,3-三羧酸 | 4756-09-6

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 丙烷-1,1,3-三羧酸
• 英文名称: propane-1,1,3-tricarboxylic acid
• 英文别名: Propan-1,1,3-tricarbonsaeure；1,3-propane-tricarboxylic acid；1,3,3-Propanetricarboxylic acid
• CAS: 4756-09-6
• 化学式: C₆H₈O₆
• 分子量: 176.126
• InChiKey: BBPLUGJBEGWJCV-UHFFFAOYSA-N

物化性质

• 熔点：
  123 °C
• 沸点：
  392.8±27.0 °C(Predicted)
• 密度：
  1.574±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.6
• 重原子数：
  12
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  112
• 氢给体数：
  3
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  丙烷-1,1,3-三羧酸 在 氯仿 、 三(2-氯乙基)胺 、 硫酸 作用下， 生成 2,4-二氨基丁酸
  参考文献：
  名称：

  The Preparation of Diamino Acids via the Schmidt Reaction

  摘要：

  DOI：

  10.1021/jo50001a009
• 作为产物：
  描述：

  3-环己烯-1-甲酸 在 tris(2,2'-bipyridyl)ruthenium dichloride 、 chloropentamminecobalt(III)(2+) 、 [RuII(TPA)(H2O)2]2+ 作用下， 以 重水 为溶剂， 生成 丙烷-1,1,3-三羧酸
  参考文献：
  名称：

  钌（II）-吡啶胺配合物高效高效选择性催化光催化氧化水中的有机物

  摘要：

  在Ru II-水性络合物作为氧化催化剂，[Ru II（bpy）3 ] 2+作为光敏剂和电子介体以及Co III络合物作为牺牲氧化剂的存在下，对有机底物（例如醇）进行了光催化氧化。（请参阅方案）。催化系统显示出高效率，可实现超过8000的周转次数。

  DOI：

  10.1002/chem.201203430

文献信息

• [EN] PIGMENT DISPERSION, INK COMPOSITION INCLUDING PIGMENT DISPERSION, AND COLOR FILTER YELLOW RESIST COMPOSITION INCLUDING PIGMENT DISPERSION<br/>[FR] DISPERSION DE PIGMENT, COMPOSITION D'ENCRE LA CONTENANT, ET COMPOSITION DE RÉSERVE JAUNE POUR FILTRE COULEUR CONTENANT LA DISPERSION DE PIGMENT
  申请人：CANON KK

  公开号：WO2012153669A1

  公开（公告）日：2012-11-15

  The present invention provides a pigment dispersion excellent in dispersibility. Furthermore, the present invention provides a color filter yellow resist composition and an ink composition, which include the pigment dispersion. A pigment dispersion containing at least a compound represented by General formula (1) and a yellow pigment represented by General formula (2) in a dispersion medium and a method for manufacturing the same are provided. Furthermore, a color filter yellow resist composition and an ink composition are provided, wherein images can be displayed with high spectral characteristics and high display contrast because the brightness is high and the hue of yellow is excellent.

  本发明提供一种色素分散体，其分散性能优异。此外，本发明提供一种包括该色素分散体的彩色滤光片黄色抗蚀组合物和油墨组合物。提供一种包含至少一种由通用公式（1）表示的化合物和一种由通用公式（2）表示的黄色色素的色素分散体，以及其制备方法。此外，提供一种彩色滤光片黄色抗蚀组合物和油墨组合物，其中可以显示具有高光谱特性和高显示对比度的图像，因为亮度高且黄色的色调优异。
• [EN] MULTIVALENT NEURAMINIDASE INHIBITOR CONJUGATES<br/>[FR] CONJUGUES INHIBITEURS DE LA NEURAMINIDASE MULTIVALENTS
  申请人：BIOTA SCIENT MANAGEMENT

  公开号：WO2002020514A1

  公开（公告）日：2002-03-14

  The invention relates to a multimeric compound or a pharmaceutically acceptable salt or derivative thereof which comprises three or more neuraminidase-binding groups attached to a spacer or linking group, in which the neuraminidase-binding group is a compound which binds to the active site of influenza virus neuraminidase, but is not cleaved by the neuraminidase. The invention also relates to processes for the preparation of the multimeric compound defined above, pharmaceutical compositions containing them or methods for the treatment and/or prophylaxis of a viral infection involving them.

  本发明涉及一种多聚化合物或其药学上可接受的盐或衍生物，其包括三个或更多与间隔物或连接基团相连的神经氨酸酶结合基团，其中神经氨酸酶结合基团是一种结合到流感病毒神经氨酸酶活性位点的化合物，但不被神经氨酸酶水解。本发明还涉及上述多聚化合物的制备方法、包含它们的药物组合物或使用它们治疗和/或预防病毒感染的方法。
• Biodegradable coating
  申请人：Tuominen Jukka

  公开号：US20050080223A1

  公开（公告）日：2005-04-14

  The object of the present invention is a biodegradable polymer network and methods to make it. The polymer network consists of a cross-linked polyester resin, which is composed of hydroxy acid units, structural units derived from an unsaturated bifunctional monomer, and structural units derived from a polyol monomer. The polyester resin is produced directly by a polyoon-densation reaction, after which it is cross-linked to a polymer of high molecular weight The polyester can be co-polymerised with a co-monomer increasing flexibility, or be blended with a reactive macromonomer, which adds elasticity and crosslinking density. The prepared polymer network can be especially used to coat continuous or singular objects made of fibrous, porous, biomass based or inorganic materials, or as a blending component in these, or used to impregnate these in order to induce water durability, barrier properties, elasticity, coherence or mechanical strength.

  本发明的目标是一种可生物降解的聚合物网络及其制备方法。该聚合物网络由交联的聚酯树脂组成，该聚酯树脂由羟酸单元、来自不饱和双官能团单体的结构单元和来自多元醇单体的结构单元组成。聚酯树脂通过聚缩酰胺反应直接制备，随后与高分子量的聚合物交联。聚酯可以与共聚单体共聚以增加柔性，或与反应性大分子单体混合，以增加弹性和交联密度。制备的聚合物网络可以用于涂覆由纤维、多孔、生物质基或无机材料制成的连续或单个物体，或作为这些物体的混合组分，或用于浸渍这些物体以诱导耐水性、隔离性、弹性、连贯性或机械强度。
• Phenylindoles for the treatment of HIV
  申请人：IDENIX PHARMACEUTICALS INC.

  公开号：US20040180888A1

  公开（公告）日：2004-09-16

  The invention as disclosed herein is a method and composition for the treatment of HIV in humans and other host animals, that includes the administration of an effective HIV treatment amount of a phenylindole as described herein or a pharmaceutically acceptable salt or prodrug thereof, optionally in a pharmaceutically acceptable carrier. The compounds of this invention either possess antiviral (i.e., anti-HIV) activity, or are metabolized to a compound that exhibits such activity.

  本发明公开了一种用于治疗人类和其他宿主动物HIV的方法和组合物，包括在药学上可接受的载体中投予本文所述的苯基吲哚或其药学上可接受的盐或前药的有效HIV治疗量。本发明化合物具有抗病毒（即抗HIV）活性，或代谢成表现出这种活性的化合物。
• Platinum-containing compounds exhibiting cytostatic activity, synthesis and methods of use
  申请人：Gao Qingzhi

  公开号：US20060205677A1

  公开（公告）日：2006-09-14

  Platinum containing compounds exhibiting cytostatic activity, methods of synthesizing platinum-containing compounds exhibiting cytostatic activity pharmaceutical compositions comprising platinum containing compounds, and methods of using such compounds and compositions for treating cancer are disclosed.

  本发明公开了含铂化合物，表现出细胞静止活性的方法，制备含铂化合物表现出细胞静止活性的制剂，以及使用这些化合物和制剂治疗癌症的方法。