4,5-bis(3-methylthiophen-2-yl)-2-phenyl-1H-imidazole | 1351459-99-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 4,5-bis(3-methylthiophen-2-yl)-2-phenyl-1H-imidazole
• CAS: 1351459-99-8
• 化学式: C₁₉H₁₆N₂S₂
• 分子量: 336.481
• InChiKey: NXFAFMQWFIFNMY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.15
• 重原子数：
  23.0
• 可旋转键数：
  3.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  28.68
• 氢给体数：
  1.0
• 氢受体数：
  3.0

反应信息

• 作为反应物：
  描述：

  4,5-bis(3-methylthiophen-2-yl)-2-phenyl-1H-imidazole 在 溶剂黄146 、 N-溴代丁二酰亚胺(NBS) 、 sodium hydroxide 作用下， 以 苯 、 水 为溶剂， 反应 4.0h， 以81%的产率得到4,5-bis(5-bromo-3-methylthiophen-2-yl)-2-phenyl-1H-imidazole
  参考文献：
  名称：

  Imidazole-based dithienylethenes as a selective chemosensors for iron(III) ions

  摘要：

  Four novel imidazole-based dithienylethenes have been successfully synthesized in good yields. Their structures have been confirmed by NMR spectrometry, mass spectrometry, and elemental analyses. UV/Vis absorption spectra indicated that these dithienylethenes can easily isomerize between the open-ring and closed-ring isomers upon irradiation with UV or visible light in solution, and that the respective closed-ring isomers show decreased fluorescence properties compared with the open-ring isomers. Moreover, the open-ring and closed-ring isomers display high selectivity toward Fe3+, such that the addition of Fe3+ obviously suppresses their fluorescence intensity. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.dyepig.2011.08.005
• 作为产物：
  描述：

  3-甲基噻吩 在 aluminum (III) chloride 、 ammonium acetate 、 溶剂黄146 作用下， 以 二硫化碳 为溶剂， 反应 1.0h， 生成 4,5-bis(3-methylthiophen-2-yl)-2-phenyl-1H-imidazole
  参考文献：
  名称：

  Imidazole-based dithienylethenes as a selective chemosensors for iron(III) ions

  摘要：

  Four novel imidazole-based dithienylethenes have been successfully synthesized in good yields. Their structures have been confirmed by NMR spectrometry, mass spectrometry, and elemental analyses. UV/Vis absorption spectra indicated that these dithienylethenes can easily isomerize between the open-ring and closed-ring isomers upon irradiation with UV or visible light in solution, and that the respective closed-ring isomers show decreased fluorescence properties compared with the open-ring isomers. Moreover, the open-ring and closed-ring isomers display high selectivity toward Fe3+, such that the addition of Fe3+ obviously suppresses their fluorescence intensity. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.dyepig.2011.08.005