2-tert-pentyloxy-ethanol | 3249-45-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-tert-pentyloxy-ethanol
• 英文别名: Aethylenglykol-mono-tert.-pentylaether；2-tert-Pentyloxy-aethanol；2-(2-Methylbutan-2-yloxy)ethanol
• CAS: 3249-45-4
• 化学式: C₇H₁₆O₂
• 分子量: 132.203
• InChiKey: KGRYJQHZLUAEES-UHFFFAOYSA-N

物化性质

• 沸点：
  168.4 °C(Press: 745.4 Torr)
• 密度：
  0.9145 g/cm3(Temp: 25 °C)

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  9
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  环氧乙烷 、 2-甲基-2-丁醇 在 acidic aluminium fluoro silicate 作用下， 生成 2-tert-pentyloxy-ethanol
  参考文献：
  名称：

  β-Amoxyethyl Esters of p-Aminobenzoic Acid

  摘要：

  DOI：

  10.1021/ja01300a010

文献信息

• OPTICAL RECORDING MEDIUM AND COMPOUND USED FOR THE SAME
  申请人：SHIOZAKI Hiroyoshi

  公开号：US20090306376A1

  公开（公告）日：2009-12-10

  A compound comprising a ring structure including a ring composed of four carbon atoms and two nitrogen atoms and a substituted or unsubstituted amino group bonded to the ring structure.

  一种化合物，包括一个环结构，其中包括由四个碳原子和两个氮原子组成的环，以及与环结构相结合的取代或未取代的氨基团。
• [EN] ACID DYES, METHODS FOR THE PRODUCTION THEREOF AND THEIR USE<br/>[FR] COLORANTS ACIDES, PROCÉDÉS POUR LEUR FABRICATION ET LEUR UTILISATION
  申请人：DYSTAR COLOURS DISTRIB GMBH

  公开号：WO2015062927A1

  公开（公告）日：2015-05-07

  Dyes according to formula (1): the production and use thereof.

  根据公式（1）染料的制备和使用。
• Carboxamide Spirolactam Cgrp Receptor Antagonists
  申请人：Williams M. Theresa

  公开号：US20070293470A1

  公开（公告）日：2007-12-20

  The present invention is directed to compounds of Formula I: I (where variables A 1 , A 2 , B, J, K, m, n, R 4 , R 5a , R 5b and R 5c are as defined herein) useful as antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as headache, migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.

  本发明涉及式I的化合物：I（其中变量A1、A2、B、J、K、m、n、R4、R5a、R5b和R5c如本文所定义），用作CGRP受体的拮抗剂，并用于治疗或预防涉及CGRP的疾病，例如头痛、偏头痛和群头痛。本发明还涉及包含这些化合物的药物组合物以及这些化合物和组合物在预防或治疗涉及CGRP的疾病中的使用。
• Cgrp Receptor Antagonists
  申请人：Burgey Christopher S.

  公开号：US20080113966A1

  公开（公告）日：2008-05-15

  Compounds of Formula (I): and Formula (II): (where variables R 2 , R 4 , A, B, D, W, X, Y and Z are as defined herein) useful as antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as headache, migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.

  式(I)和式(II)的化合物(其中变量R2、R4、A、B、D、W、X、Y和Z的定义如本文所述)，可用作CGRP受体拮抗剂，用于治疗或预防CGRP参与的疾病，如头痛、偏头痛和集群头痛。本发明还涉及包含这些化合物的制药组合物以及使用这些化合物和组合物预防或治疗CGRP参与的这些疾病的用途。
• Process for the hydrolysis of glycol dialkyl ether to a monoalkyl ether and tertiary alcohol or tertiary olefin
  申请人：MARUZEN PETROCHEMICAL CO., LTD.

  公开号：EP0038129A1

  公开（公告）日：1981-10-21

  A process is described for converting glycol dialkyl ether without substantial formation of olefin oligomers by reaction with water, comprising reacting a feed glycol di-tertiary alkyl ether represented by structural formula (A) with water using a strongly acidic cation-exchange resin as a catalyst and a reaction temperature of from 40°C to 150°C under a pressure of from 1 to 70 kg/cm2 (absolute pressure) in a molar ratio of water/feed glycol di-tertiary alkyl ether represented by the structural formula (A) of from 0.05/1 to 60/1, to convert the ether of formula (A) into at least one of (1) glycol mono-tertiary alkyl ether represented by the structural formula (B) and tertiary alcohol represented by the structural formula (C), and (2) tertiary olefin represented by the structural formula (D); wherein (A), (B), (C), and (D) are as follows: wherein R1 represents a methyl group, an ethyl group, or a propyl group, n represents an integer of from 1 to 10, and R, represents an alkylene group having from 2 to 14 carbon atoms, and the total number of carbon atoms in the group -(R2-O)n- is from 2 to 30.

  描述了一种通过与水反应转化乙二醇二烷基醚而不会大量形成烯烃低聚物的工艺，包括使用强酸性阳离子交换树脂作为催化剂，在 1 至 70 kg/cm2（绝对压力）的压力下，在 40°C 至 150°C 的反应温度和水/结构式（A）代表的乙二醇二烷基醚的摩尔比为 0.05/1至60/1，将式(A)的醚转化为(1)结构式(B)代表的乙二醇单叔烷基醚和结构式(C)代表的叔醇，以及(2)结构式(D)代表的叔烯烃中的至少一种；其中(A)、(B)、(C)和(D)如下： 其中 R1 代表甲基、乙基或丙基，n 代表 1 至 10 的整数，R 代表具有 2 至 14 个碳原子的亚烷基，且基团-(R2-O)n-中的碳原子总数为 2 至 30。