1,2-bis(5-amino-1H-benzimidazol-2-yl)benzene | 313666-93-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并咪唑类
• 英文名称: 1,2-bis(5-amino-1H-benzimidazol-2-yl)benzene
• 英文别名: ChemDiv3_000496；2-[2-(6-amino-1H-benzimidazol-2-yl)phenyl]-3H-benzimidazol-5-amine
• CAS: 313666-93-2
• 化学式: C₂₀H₁₆N₆
• 分子量: 340.387
• InChiKey: ZJSIITUXTQETKU-UHFFFAOYSA-N

物化性质

• 沸点：
  760.3±70.0 °C(Predicted)
• 密度：
  1.442±0.06 g/cm3(Predicted)
• 溶解度：
  在DMSO中的溶解度≥15mg/mL

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  26
• 可旋转键数：
  2
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  109
• 氢给体数：
  4
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1,2-bis(5-amino-1H-benzimidazol-2-yl)benzene 、 氯乙酰氯 在 吡啶 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 0.5h， 生成
  参考文献：
  名称：

  双（苯并咪唑）吡啶衍生物是一类新的诱导和稳定G-四链体的配体。

  摘要：

  已经制备了两种新的双（苯并咪唑）芳基衍生物，其中一种已经显示出诱导并稳定了G-四链体的形成。

  DOI：

  10.1039/b807916a
• 作为产物：
  描述：

  1,2-双(5-硝基-1H-苯并咪唑-2-基)苯 在 盐酸 、 tin(II) chloride dihdyrate 、 溶剂黄146 作用下， 以 水 为溶剂， 反应 6.5h， 以48%的产率得到1,2-bis(5-amino-1H-benzimidazol-2-yl)benzene
  参考文献：
  名称：

  双（苯并咪唑）吡啶衍生物是一类新的诱导和稳定G-四链体的配体。

  摘要：

  已经制备了两种新的双（苯并咪唑）芳基衍生物，其中一种已经显示出诱导并稳定了G-四链体的形成。

  DOI：

  10.1039/b807916a

文献信息

• Preparation and characterization of new soluble benzimidazole–imide copolymers
  作者：M. Berrada、F. Carriere、Y. Abboud、A. Abourriche、A. Benamara、N. Lajrhed、M. Kabbaj、M. Berrada

  DOI：10.1039/b205150h

  日期：——

  The present necessity to use heat-resistant materials in electronics justifies the scientific interest in different heterocyclic polymers. This paper is especially concerned with the preparation of novel heat-resistant polyimides having bisbenzimidazole moieties in the main chain and their applications as dielectric films. A soluble copolyimide was prepared by a two-step synthesis from aromatic dianhydrides and aromatic diamines. The bisbenzimidazole diamine was prepared by reduction of the corresponding dinitro compound. The diamine was reacted with various aromatic dianhydrides to prepare a series of alternating benzimidazole–imide copolymers via the poly(amic acid) precursors and thermal or chemical imidization. Monomers and polymers were characterized by conventional methods and their physical properties such as solution viscosity, solubility properties, thermal stability and thermal behaviour were studied. All copolymers were obtained in high yields having inherent viscosities ηinh that ranged from 0.60 to 0.98 dL g−1. Thin films of the copolymer were tough and flexible, having tensile strengths as high as 100 MPa. Glass transition temperatures were observed between 275 and 328 °C. Thermogravimetric analyses indicated that the thermal degradation of poly(benzimidazole–imide) occurs around 530 °C, which is ca. 80 °C higher than polyimide, confirming that the introduction of the bisbenzimidazole component improved the thermal stability of polyimide.

  目前电子领域对耐热材料的需求使得不同的杂环聚合物引起了科学界的关注。本文特别关注含有双苯并咪唑基团的新型耐热聚酰亚胺的制备及其作为绝缘薄膜的应用。通过对芳香二酐和芳香二胺的两步合成，制备了一种可溶性共聚酰亚胺。双苯并咪唑二胺是通过还原相应的二硝基化合物制备的。该二胺与多种芳香二酐反应，通过聚（酰胺酸）前驱体及热或化学酰亚胺化反应制备出一系列交替的苯并咪唑-酰亚胺共聚物。单体和聚合物通过常规方法进行了表征，并研究了其物理性质，如溶液粘度、溶解特性、热稳定性和热行为。所有共聚物都以高产率获得，固有粘度ηinh范围为0.60至0.98 dL g⁻¹。共聚物的薄膜坚韧且柔韧，拉伸强度高达100 MPa。玻璃转变温度在275至328°C之间。热重分析表明，聚（苯并咪唑-酰亚胺）的热降解发生在约530°C，这比聚酰亚胺高出约80°C，确认了双苯并咪唑组分的引入提高了聚酰亚胺的热稳定性。
• Bis-benzimidazoles and related compounds as potassium channel modulators
  申请人：ICAgen, Inc.

  公开号：US20040029925A1

  公开（公告）日：2004-02-12

  The present invention provides a genus of bis-benzimidazole compounds, methods and pharmaceutical compositions that are useful as modulators of potassium ion channels. The compounds of the invention are of use in both therapeutic and diagnostic methods.
• LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT
  申请人：CHI MEI CORPORATION

  公开号：US20140024753A1

  公开（公告）日：2014-01-23

  A liquid crystal alignment agent contains a polymer and a solvent. The polymer is obtained by subjecting a mixture including a tetracarboxylic dianhydride component and a diamine component to a reaction. The diamine component includes a diamine compound of formula (I) defined herein, a benzimidazole-group-containing diamine compound, and a diamine compound other than the diamine compound of formula (I) and the benzimidazole-group-containing diamine compound. The liquid crystal alignment agent has superior processing stability, and a liquid crystal display element made from the aforesaid liquid crystal alignment agent has superior reliability.
• COATING COMPOSITION INCLUDING FUNCTIONALIZED GRAPHENE OXIDE, METHOD FOR FORMING STACKED STRUCTURE USING THE SAME AND METHOD FOR MANUFACTURING DISPLAY DEVICE USING THE SAME
  申请人：Samsung Display Co., LTD.

  公开号：US20210104672A1

  公开（公告）日：2021-04-08

  A coating composition includes a graphene oxide and a solvent. At least one of a carboxyl group and an epoxide group of the graphene oxide is functionalized by an amine. The amine has an activation energy to an epoxide group of the graphene oxide of about −3 kcal/mol to about 8 kcal/mol. A method of forming a stacked structure using the coating composition is provided. A method of manufacturing a display device using the coating composition is provided.
• US7132439B2
  申请人：——

  公开号：US7132439B2

  公开（公告）日：2006-11-07