3-butyl-3-hydroxy-heptanenitrile | 100049-50-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3-butyl-3-hydroxy-heptanenitrile
• 英文别名: 3-Butyl-3-hydroxy-heptannitril；3-Butyl-3-hydroxyheptanenitrile
• CAS: 100049-50-1
• 化学式: C₁₁H₂₁NO
• 分子量: 183.294
• InChiKey: AIGZGGKOLGKMRB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  13
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.91
• 拓扑面积：
  44
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  5-壬酮 、 溴乙腈 在 四氢呋喃 、 mercury dichloride 、 锌 作用下， 生成 3-butyl-3-hydroxy-heptanenitrile
  参考文献：
  名称：

  Applied anatomy of the V-shaped fibular osteomyocutaneous flap in reconstruction of the hindfoot

  摘要：

  To establish the applied anatomy of the V-shaped fibular osteomyocutaneous flap pedicled on the peroneal vessels, cadaver dissections were made in 60 lower limbs and 40 calcanei were examined to sum up the features of calcaneal biomechanics on the stability of the foot and the blood supply of the fibular osteomyocutaneous flap. There were four anastomoses and large communicating branches between the lower segment of the peroneal artery and the anterior and posterior tibial arteries. The flap was well supplied by a retrograde circulation through these anastomoses. A suitable length of pedicle was 20 cm. In the sagittal section of the calcaneus passing through the center of the articular surface for the cuboid bone, the arrangement of the trabeculae formed a triangular zone. The V-shaped flap corresponds nicely with the calculated lines of stress evoked by the weight of the body. The procedure may provide a new method for hindfoot reconstruction. This flap meets the criteria outlined for composite tissue reconstruction of defects of the extremities and biomechanics of the hindfoot, especially for calcaneal and cuboid defects.

  DOI：

  10.1007/s00276-001-0215-7