nitrilotri-acetic acid trihydrazide | 80155-82-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: nitrilotri-acetic acid trihydrazide
• 英文别名: Nitrilotri-essigsaeure-trihydrazid；Triglykolamidsaeuretrihydrazid；Nitrazine；2-[bis(2-hydrazinyl-2-oxoethyl)amino]acetohydrazide
• CAS: 80155-82-4
• 化学式: C₆H₁₅N₇O₃
• 分子量: 233.23
• InChiKey: KGSXKXWCVWJCIW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.9
• 重原子数：
  16
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  169
• 氢给体数：
  6
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  nitrilotri-acetic acid trihydrazide 、 4-formylphenyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside 在 溶剂黄146 作用下， 以 水 为溶剂， 反应 0.5h， 生成
  参考文献：
  名称：

  动态组合碳水化合物库：探测伴刀豆球蛋白A凝集素的结合位点。

  摘要：

  动态组合化学（DCC）已经成为一种有效的受体/配体鉴定方法，该方法基于通过库成分的可逆相互转换生成组合库。在这项研究中，以植物凝集素伴刀豆球蛋白A为靶标，研究了此类库对碳水化合物-凝集素相互作用的实现。通过可逆的酰基hydr交换，从碳水化合物醛和酰肼连接基/骨架组分的库中生成动态碳水化合物库，从而产生包含多达474个成分的库。动态去卷积允许有效识别绑定到伴刀豆球蛋白A所需的结构特征，并选择一种强结合剂，一种三位甘露糖苷，显示IC（50）值为22 microM。

  DOI：

  10.1002/chem.200305551
• 作为产物：
  描述：

  次氮基三乙酸 在 盐酸 、 一水合肼 作用下， 生成 nitrilotri-acetic acid trihydrazide
  参考文献：
  名称：

  Curtius, Journal fur praktische Chemie (Leipzig 1954), 1917, vol. <2> 96, p. 234

  摘要：

  DOI：

文献信息

• Polyurethane coating compositions
  申请人：ICI RESINS BV

  公开号：EP0332326A2

  公开（公告）日：1989-09-13

  Aqueous selfcrosslinkable coating composition comprising an aqueous dispersion of at least one polyurethane and having hydrazine (or hydrazone) functional groups and carbonyl functional groups disposed therein to provide a selfcrosslinking reaction, in which the polyurethane polymer takes part, via azomethine formation during and/or after film formation.

  水性自交联涂料组合物，包含至少一种聚氨酯的水性分散体，其中含有肼（或腙）官能团和羰基官能团，可在成膜过程中和/或成膜后通过偶氮甲烷形成自交联反应，聚氨酯聚合物可参与该反应。
• Aqueous coating compositions
  申请人：ZENECA RESINS BV

  公开号：EP0341886A2

  公开（公告）日：1989-11-15

  An aqueous selfcrosslinkable coating composition which comprises an aqueous dispersion of at least one vinyl polymer, wherein the polymer system constituting said at least one vinyl polymer has chain-pendant amine functional groups and chain-pendant carbonyl functional groups to provide a selfcrosslinking reaction during and/or after coating formation from the composition. The vinyl polymers having both amine and carbonyl groups are also claimed.

  一种水性自交联涂料组合物，它包括至少一种乙烯基聚合物的水性分散体，其中构成所述至少一种乙烯基聚合物的聚合物体系具有链悬垂胺官能团和链悬垂羰基官能团，以便在组合物形成涂层期间和/或之后发生自交联反应。本发明还涉及同时具有胺官能团和羰基官能团的乙烯基聚合物。
• PEELABLE AQUEOUS COATING COMPOSITION AND METHOD OF TEMPORARILY PROTECTING AUTOMOBILE OUTSIDE-PLATE COATING THEREWITH
  申请人：KANSAI PAINT CO. LTD.

  公开号：EP0786501A1

  公开（公告）日：1997-07-30

  The present invention relates to a releasable aqueous coating composition containing (A) a resin dispersion containing a carbonyl group-containing copolymer aqueous dispersion and a polyhydrazide compound in such a ratio that an amount of hydrazide group is in the range of 0.02 to 3.0 equivalents per one equivalent of carbonyl group in the emulsion particle, and (B) a release assistant; and a method of temporarily protecting a finished coating film on an automobile body, which method comprises coating said coating composition onto a surface of a finished cured coating film coated onto the automobile body.

  本发明涉及一种可释放的水性涂料组合物，该组合物含有（A）含有含羰基的共聚物水性分散体和聚酰肼化合物的树脂分散体，其比例为每一个当量的羰基在乳液颗粒中含有 0.02 至 3.0 个当量的酰肼基团，以及（B）一种释放助剂；还涉及一种临时保护汽车车身成品涂膜的方法，该方法包括将所述涂料组合物涂在涂在汽车车身上的固化成品涂膜的表面上。
• Aqueous emulsion, process for producing the same and aqueous paint and aqueous printing ink comprising the same
  申请人：NIPPON POLYURETHANE INDUSTRY CO. LTD.

  公开号：EP1057843A1

  公开（公告）日：2000-12-06

  An aqueous emulsion which comprises as a resin component a self-emulsifiable copolymer in which at least one ethylenically unsaturated monomer and at least one urethane prepolymer having at least one mercapto group and at least one hydrophilic, polar group are bonded by radical polymerization or in which at least one ethylenically unsaturated monomer, at least one organic polyisocyanate, at least one compound having at least one mercapto group and at least one active hydrogen-containing group and at least one compound having at least one hydrophilic, polar group and at least one active hydrogen-containing group are bonded by urethanization reaction and radical polymerization.

  一种水性乳液，作为树脂组分包括一种自乳化共聚物，其中至少有一种乙烯基不饱和单体和至少一种具有至少一个巯基和至少一个亲水极性基团的聚氨酯预聚物通过自由基聚合键合，或至少有一种乙烯基不饱和单体、至少一种有机多异氰酸酯、至少一种具有至少一个巯基和至少一个活性含氢基团的化合物，以及至少一种具有至少一个亲水极性基团和至少一个活性含氢基团的化合物，通过氨基甲酸酯化反应和自由基聚合键合。
• Curing type water base resin composition
  申请人：KANSAI PAINT CO., LTD.

  公开号：EP1211293A2

  公开（公告）日：2002-06-05

  The present invention relates to a curing type water base resin composition comprising: (I) a copolymer obtained by copolymerizing an ethylenically unsaturated monomer (a) having a maleimide group, an ethylenically unsaturated monomer (b) having a carbonyl group and other ethylenically unsaturated monomer (c) and (II) a compound having two or more groups per molecule which are the same or different and selected from a hydrazide group, a semicarbazide group and hydrazone group and further comprising, if necessary, as an additional component: (III) a copolymer having a carbonyl group and/or (IV) a water base polyurethane resin having a carbonyl group or a hydrazine group.

  本发明涉及一种固化型水基树脂组合物，其中包括 (I) 由具有马来酰亚胺基团的乙烯基不饱和单体(a)、具有羰基的乙烯基不饱和单体(b)和其他乙烯基不饱和单体(c)共聚而得的共聚物，以及 (II) 每分子具有两个或两个以上相同或不同基团的化合物，这些基团选自肼 基、半肼基和腙基，必要时还包括作为附加组分的另一种化合物： (III) 具有羰基的共聚物和/或 (IV) 具有羰基或肼基的水基聚氨酯树脂。