Synthesis of β- and γ-Carbolines by the Palladium-Catalyzed Iminoannulation of Internal Alkynes
摘要:
[GRAPHICS]A variety of substituted beta- and gamma -carbolines have been prepared in good to excellent yields by the annulation of internal acetylenes by the tert-butylimines of N-substituted 3-iodoindole-2-carboxaldehydes and 2-haloindole-3-carboxaldehydes, respectively, in the presence of a palladium catalyst.
Synthesis of β- and γ-Carbolines by the Palladium-Catalyzed Iminoannulation of Internal Alkynes
摘要:
[GRAPHICS]A variety of substituted beta- and gamma -carbolines have been prepared in good to excellent yields by the annulation of internal acetylenes by the tert-butylimines of N-substituted 3-iodoindole-2-carboxaldehydes and 2-haloindole-3-carboxaldehydes, respectively, in the presence of a palladium catalyst.
Synthesis of <i>β</i>- and <i>γ</i>-Carbolines by the Palladium-Catalyzed Iminoannulation of Internal Alkynes
作者:Haiming Zhang、Richard C. Larock
DOI:10.1021/ol010124w
日期:2001.10.1
[GRAPHICS]A variety of substituted beta- and gamma -carbolines have been prepared in good to excellent yields by the annulation of internal acetylenes by the tert-butylimines of N-substituted 3-iodoindole-2-carboxaldehydes and 2-haloindole-3-carboxaldehydes, respectively, in the presence of a palladium catalyst.