2,3,6-三甲基环己醇 | 58210-03-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 2,3,6-三甲基环己醇
• 英文名称: 2,3,6-trimethylcyclohexanol
• 英文别名: 2,3,6-trimethylcyclohexan-1-ol
• CAS: 58210-03-0
• 化学式: C₉H₁₈O
• 分子量: 142.241
• InChiKey: HTFQSOIWEISWDY-UHFFFAOYSA-N

物化性质

• 熔点：
  37.75°C (estimate)
• 沸点：
  209.85°C (estimate)
• 密度：
  0.9117

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  2,3,6-三甲基环己醇 生成 1,2,4-三甲基环己烷
  参考文献：
  名称：

  Zelinsky; Reformatski, Chemische Berichte, 1896, vol. 29, p. 214

  摘要：

  DOI：
• 作为产物：
  描述：

  2,3,6-三甲基-环己酮 在 乙醚 、 sodium 作用下， 生成 2,3,6-三甲基环己醇
  参考文献：
  名称：

  Zelinsky; Reformatski, Chemische Berichte, 1895, vol. 28, p. 2944

  摘要：

  DOI：

文献信息

• [EN] 2-(2,4,5-TRIMETHYLCYCLOHEX-2-EN-1-YL)ACETALDEHYDE AND DERIVATIVES AND THEIR USE AS AROMA CHEMICALS<br/>[FR] 2-(2,4,5-TRIMÉTHYLCYCLOHEX-2-EN-1-YL)ACÉTALDÉHYDE ET DÉRIVÉS ET LEUR UTILISATION EN TANT QUE PRODUITS CHIMIQUES AROMATIQUES
  申请人：BASF SE

  公开号：WO2021005109A1

  公开（公告）日：2021-01-14

  The present invention relates to 2-(2,4,5-trimethylcyclohex-2-en-1-yl)acetaldehyde and derivatives thereof, to a process for preparing said compounds, to the use of 2-(2,4,5- trimethylcyclohex-2-en-1-yl)acetaldehyde or a specific derivative thereof or of mixtures of said compounds or of a stereoisomer thereof or of a mixture of two or more stereoisomers thereof as aroma chemicals; to the use of 2-(2,4,5-trimethylcyclohex-2- en-1-yl)acetaldehyde or a specific derivative thereof for modifying the scent character of a fragranced composition; to compositions containing 2-(2,4,5-trimethylcyclohex-2- en-1-yl)acetaldehyde or a specific derivative thereof or a mixture of said compounds or a stereoisomer thereof or a mixture of two or more stereoisomers thereof; and to a method of preparing a fragranced composition or for modifying the scent character of a fragranced composition, comprising incorporating 2-(2,4,5-trimethylcyclohex-2-en-1-yl)- acetaldehyde or a specific derivative thereof or a mixture of said compounds or a stereoisomer thereof or a mixture of two or more stereoisomers thereof into said composition.

  本发明涉及2-(2,4,5-三甲基环己-2-烯-1-基)乙醛及其衍生物，以及制备上述化合物的方法，将2-(2,4,5-三甲基环己-2-烯-1-基)乙醛或其特定衍生物或上述化合物的混合物或其立体异构体或两个或更多立体异构体的混合物用作香气化学品；将2-(2,4,5-三甲基环己-2-烯-1-基)乙醛或其特定衍生物用于修改带香味组合物的气味特性；含有2-(2,4,5-三甲基环己-2-烯-1-基)乙醛或其特定衍生物或上述化合物的混合物或其立体异构体或两个或更多立体异构体的组合物的组合物；以及一种制备带香味组合物或修改带香味组合物的气味特性的方法，包括将2-(2,4,5-三甲基环己-2-烯-1-基)乙醛或其特定衍生物或上述化合物的混合物或其立体异构体或两个或更多立体异构体混合物并入该组合物。
• New succinate derivatives
  申请人：Symrise AG

  公开号：EP2810934A1

  公开（公告）日：2014-12-10

  The invention relates generally to new compounds of formula (I), wherein R1, R2, R3, R4, R5, R6, R7 are independently of one another and denote hydrogen, hydroxyl, C1- C6-alkyl group or R6 and R7 form together a C5-C6 ring system, and wherein n = 0, 1, 2, 3, or 4. Moreover, the invention relates to the use of one or more compounds of formula (I) in cosmetic or pharmaceutical compositions, which are preferably dermatological compositions and are preferably used topically.

  该发明涉及一般的新化合物，其化学式为（I），其中R1、R2、R3、R4、R5、R6、R7彼此独立，并分别表示氢、羟基、C1-C6烷基基团或R6和R7共同形成一个C5-C6环系统，其中n = 0、1、2、3或4。此外，该发明涉及在化妆品或药物组合物中使用一个或多个化合物的化学式（I），这些组合物通常是皮肤科组合物，通常是局部使用的。
• [EN] NEW SUCCINATE DERIVATIVES<br/>[FR] NOUVEAUX DÉRIVÉS DE SUCCINATE
  申请人：SYMRISE AG

  公开号：WO2014198602A1

  公开（公告）日：2014-12-18

  The invention relates generally to new compounds of formula (I), wherein R1, R'1, R2, R'2, R3, R'3, R4 R'4, R5, R'5, R6, R7 are independently of one another and denote hydrogen, hydroxyl, C1 to C6-alkyl group or R6 and R7 form together a C5-C6 ring system, and wherein n = 0, 1, 2, 3, or 4. Moreover, the invention relates to the use of one or more compounds of formula (I) in cosmetic or pharmaceutical compositions, which are preferably dermatological compositions and are preferably used topically.

  该发明涉及一般公式(I)的新化合物，其中R1、R'1、R2、R'2、R3、R'3、R4、R'4、R5、R'5、R6、R7独立地表示氢、羟基、C1到C6-烷基基团，或者R6和R7一起形成一个C5-C6环系统，其中n = 0、1、2、3或4。此外，该发明涉及在化妆品或药用组合物中使用一个或多个公式(I)的化合物，这些组合物通常是皮肤科组合物，通常是局部使用的。
• CYCLOHEXYL CARBAMATE COMPOUNDS AS ANTI-AGEING ACTIVES
  申请人：Küper Thomas

  公开号：US20110294876A1

  公开（公告）日：2011-12-01

  The present invention relates to the cosmetic, dermatological or therapeutic use of compounds of formula (I) given below, in particular as anti-ageing actives. wherein A denotes wherein X, Y and Z independently of one another denote hydrogen, C1-C4-alkyl or C2-C4-alkenyl, wherein optionally two of the radicals X, Y and Z are covalently bonded to one another under formation of a bicyclic ring system, in such a bicyclic ring system two of the radicals X, Y and Z together preferably form a radical having 1 to 4 carbon atoms, preferably a hydrocarbon radical having 1 to 3 carbon atoms, B denotes NR 1 R 2 , wherein R 1 denotes hydrogen or an organic radical having 1 to 14 carbon atoms, R 2 denotes an organic radical having 1 to 14 carbon atoms, and wherein optionally R 1 and R 2 are covalently bonded to one another, preferably so that B is a 3 to 8 membered ring. The invention further relates to corresponding methods and to compositions and cosmetic, dermatological or pharmaceutical preparations (compositions) comprising one or more compounds of formula (I) and one or more further anti-ageing actives. The invention further relates to compounds of formula (I) as a drug, their use for the preparation of a pharmaceutical composition and to certain novel compounds of formula (I).

  本发明涉及化妆品、皮肤学或治疗用途的化合物的使用，其化学式（I）如下，特别是作为抗衰老活性成分。其中A代表其中X、Y和Z分别表示氢、C1-C4-烷基或C2-C4-烯基，其中可选地，X、Y和Z中的两个基以形成二环戊二烯环系统的方式共价结合在一起，在这样的二环戊二烯环系统中，X、Y和Z中的两个基一起优选地形成具有1至4个碳原子的基，优选地是具有1至3个碳原子的烃基，B代表NR1R2，其中R1代表氢或具有1至14个碳原子的有机基，R2代表具有1至14个碳原子的有机基，可选地R1和R2共价结合在一起，优选地使B成为一个3至8成员环。该发明还涉及相应的方法、包含一个或多个化学式（I）化合物和一个或多个其他抗衰老活性成分的化妆品、皮肤学或药用制剂（组合物）。该发明还涉及化学式（I）化合物作为药物，它们用于制备药物组合物的用途，以及化学式（I）的某些新化合物。
• CYCLOHEXYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS
  申请人：Meyer Imke

  公开号：US20130137710A1

  公开（公告）日：2013-05-30

  The present invention relates to the cosmetic, dermatological or therapeutic use of certain cyclohexyl carbamate compounds of formula (I) given below, preferably as anti-cellulite actives. The invention further relates to compositions and cosmetic, dermatological or therapeutic products comprising such compounds of formula (I), which are preferably suitable for the prophylaxis (prevention) and cosmetic treatment (combating) of cellulite in human beings, corresponding methods and novel compounds of formula (I) wherein A denotes wherein X, Y and Z independently of one another denote hydrogen, C1-C4-alkyl or C2-C4-alkenyl, wherein optionally two of the radicals X, Y and Z are covalently bonded to one another under formation of a bicyclic ring system, in such a bicyclic ring system two of the radicals X, Y and Z together preferably form a radical having 1 to 4 carbon atoms, preferably a hydrocarbon radical having 1 to 3 carbon atoms, B denotes NR 1 R 2 , wherein R 1 denotes hydrogen or an organic radical having 1 to 14 carbon atoms, R 2 denotes an organic radical having 1 to 14 carbon atoms, and wherein optionally R 1 and R 2 are covalently bonded to one another, preferably so that B is a 3 to 8 membered ring.

  本发明涉及以下式子（I）所示的某些环己基氨基甲酸酯化合物的化妆品、皮肤科或治疗用途，优选作为抗脂肪纹活性剂。本发明还涉及包含该式（I）化合物的组合物和化妆品、皮肤科或治疗产品，这些化合物优选用于人类的脂肪纹预防和美容治疗，以及相应的方法和新型式（I）化合物。其中，A表示......，X、Y和Z分别独立地表示氢、C1-C4烷基或C2-C4烯基，其中可选地，X、Y和Z中的两个基团彼此共价结合形成二环环系统，在这样的二环环系统中，X、Y和Z中的两个基团一起优选形成具有1至4个碳原子的基团，优选为具有1至3个碳原子的碳氢基团，B表示NR1R2，其中R1表示氢或具有1至14个碳原子的有机基团，R2表示具有1至14个碳原子的有机基团，可选地，R1和R2彼此共价结合，优选使得B为3至8个成员的环。