(1-甲基环己基)-苯基甲酮 | 2892-99-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: (1-甲基环己基)-苯基甲酮
• 英文名称: 1-Benzoyl-1-methyl-cyclohexan
• 英文别名: <1-Methyl-cyclohexyl>-phenyl-keton；(1-Methylcyclohexyl)(phenyl)methanone；(1-methylcyclohexyl)-phenylmethanone
• CAS: 2892-99-1
• 化学式: C₁₄H₁₈O
• 分子量: 202.296
• InChiKey: XMCYCMCBVWLZCY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  (1-甲基环己基)-苯基甲酮 在 sodium amide 、 甲苯 作用下， 生成 1-methyl-cyclohexylcarboxamide
  参考文献：
  名称：

  The Synthesis of Some Teritary Carbinamines as Vasopressor Agents

  摘要：

  DOI：

  10.1021/ja01098a033
• 作为产物：
  描述：

  (1-甲基-环己-3-烯基)-苯基酮 在 镍 作用下， 生成 (1-甲基环己基)-苯基甲酮
  参考文献：
  名称：

  Jacquier et al., Bulletin de la Societe Chimique de France, 1956, p. 1653,1664

  摘要：

  DOI：

文献信息

• <i>N</i>-Heterocyclic Carbene-Catalyzed Decarboxylative Alkylation of Aldehydes
  作者：Takuya Ishii、Yuki Kakeno、Kazunori Nagao、Hirohisa Ohmiya

  DOI：10.1021/jacs.9b00880

  日期：2019.3.6

  N-heterocyclic carbene catalysis promoted the unprecedented decarboxylative coupling of aryl aldehydes and tertiary or secondary alkyl carboxylic acid-derived redox-active esters to produce aryl alkyl ketones. The mild and transition-metal-free reaction conditions are attractive features of this method. The power of this protocol was demonstrated by the functionalization of pharmaceutical drugs and natural

  我们发现 N-杂环卡宾催化促进了芳醛和叔或仲烷基羧酸衍生的氧化还原活性酯的前所未有的脱羧偶联，以生产芳烷基酮。温和且不含过渡金属的反应条件是该方法的吸引人的特征。药物和天然产物的功能化证明了该协议的力量。提出了一种反应途径，包括从 Breslow 中间体的烯醇化物形式到氧化还原酯的单电子转移，然后再结合所得自由基对以形成碳-碳键。
• <i>N</i>-Heterocyclic Carbene-Catalyzed Radical Relay Enabling Vicinal Alkylacylation of Alkenes
  作者：Takuya Ishii、Kenji Ota、Kazunori Nagao、Hirohisa Ohmiya

  DOI：10.1021/jacs.9b07194

  日期：2019.9.11

  The N-heterocyclic carbene-catalyzed radical relay enables the vicinal alkylacylation of styrenes, acrylates and acrylo-nitrile using aldehydes and tertiary alkyl carboxylic acid-derived redox-active esters. This protocol introduces tertiary alkyl groups and acyl groups to C-C double bonds with complete regioselectivity to produce functionalized ketone derivatives. The radical relay mechanism involves

  N-杂环卡宾催化的自由基中继能够使用醛和叔烷基羧酸衍生的氧化还原活性酯对苯乙烯、丙烯酸酯和丙烯腈进行邻位烷基酰化。该协议将叔烷基和酰基引入 CC 双键，具有完全的区域选择性，以产生功能化的酮衍生物。自由基中继机制涉及从 Breslow 中间体的烯醇化物形式的单电子转移和所得烷基自由基与烯烃的自由基加成，然后是自由基 - 自由基偶联。
• Restricted rotation due to the lack of free space within a capsule translates into product selectivity: photochemistry of cyclohexyl phenyl ketones within a water-soluble organic capsule
  作者：Revathy Kulasekharan、Rajib Choudhury、Rajeev Prabhakar、V. Ramamurthy

  DOI：10.1039/c0cc05337f

  日期：——

  The rotational mobility of organic guest molecules when included within a confined capsule is restricted and this feature could be translated into product selectivity as established with the photochemical behavior of cyclohexyl phenyl ketones.

  当有机客体分子包含在密闭胶囊中时，其旋转迁移率受到限制，并且该特征可以转化为产物选择性，这是通过环己基苯基酮的光化学行为确定的。
• Modification of photochemical reactivity by zeolites: Cation enhanced α-cleavage of aryl alkyl ketones included in faujasites
  作者：V. Ramamurthy、D.R. Corbin、N.J. Turro、Y. Sato

  DOI：10.1016/s0040-4039(01)93482-3

  日期：1989.1

  The yield of Norrish type I products are significantly enhanced when aryl alkyl ketones are photolyzed in the cages of faujasite type zeolites. Exchangeable cations present within the supercages are suggested to be responsible for such an enhanced α-cleavage.

  当在八面沸石型沸石的笼中光解芳基烷基酮时，Norrish I型产品的收率显着提高。认为存在于超笼中的可交换阳离子是这种增强的α裂解的原因。
• Organic Phase Change Carriers Containing Nanoparticles, Phase Change Inks Including Same and Methods for Making Same
  申请人：Breton Marcel P.

  公开号：US20070283846A1

  公开（公告）日：2007-12-13

  Disclosed is an organic phase change carrier and a method for forming same, and a phase change ink including same. The organic phase change carrier comprises a colloidal dispersion of nanoparticles exhibiting a substantially uniform distribution of said nanoparticles discretely distributed therewithin, at least one curable monomer; a phase change inducing component, and an initiator. The organic phase change carrier exhibits a substantially uniform distribution of the nanoparticles so that they are discretely distributed therewithin, and are substantially resistant to the aggregation of the nanoparticles distributed therewithin.

  本发明公开了一种有机相变载体及其制备方法，以及包括该载体的相变墨水。所述有机相变载体包括一种胶体分散体，其中包含一种呈现出基本均匀分布的纳米粒子，至少一种可固化单体，一种相变诱导成分和一种引发剂。所述有机相变载体呈现出纳米粒子的基本均匀分布，以便它们被离散地分布在其中，并且对分布在其中的纳米粒子聚集具有相当的抵抗力。