(1,1'-dimethyl-2,2'-biimidazole-N(3),N(3'))diiodiplatinum(II) | 220070-49-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: (1,1'-dimethyl-2,2'-biimidazole-N(3),N(3'))diiodiplatinum(II)
• 英文别名: [PtI2(Me2bim)]；1-methyl-2-(1-methylimidazol-2-yl)imidazole;platinum(2+);diiodide
• CAS: 220070-49-5
• 化学式: C₈H₁₀I₂N₄Pt
• 分子量: 611.083
• InChiKey: HGMPRQRPJMYNPJ-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  -5.17
• 重原子数：
  15
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  35.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  (1,1'-dimethyl-2,2'-biimidazole-N(3),N(3'))diiodiplatinum(II) 在 AgNO₃ 作用下， 以 硝酸 、 二甲基亚砜 为溶剂， 生成 [[PtBr(DMSO)]2(Me2bim)]
  参考文献：
  名称：

  Pd(II) and Pt(II) complexes of 2,2′-biimidazole and its N,N′-dimethyl derivative. The crystal structure of [{PtBr(DMSO)}2(Me2bim)] (Me2bim=N,N′-dimethyl-2,2′-biimidazole)

  摘要：

  The complexes [PdCl2(LL)] and [PtX2(LL)] [X = Cl, Br or I; LL = 2,2'-biimidazole (H(2)bim) or N,N'-dimethyl-2,2'-biimidazole (Me(2)bim)] were prepared and characterized spectroscopically. The effects of the chloro compounds on plasmid DNA conformation were studied by electrophoresis in agarose gels, and that of [PtCl2(H(2)bim)] on calf thymus DNA by circular dichroism spectroscopy. The observation that these effects were adversely affected by addition of DMSO (originally used with [PtCl2(Me(2)bim)], to improve its solubility) prompted a study of the solvolysis of [PtCl2(H(2)bim)] by this solvent. H-1 and Pt-195 NMR, and electrospray mass spectra, showed the solvolysis of both Pt-Cl and Pt-N bonds, the release of the ligand H2bim, and the formation of several polynuclear species. X-ray diffractometry of the dinuclear Pt(I) compound [{PtBr(DMSO)}(2)(Me(2)bim)] showed the ligand Me(2)bim to bridge through its non-methylated N atoms between two platinum atoms, the coordination spheres of which were each completed by a Br- ligand, the S atom of a DMSO molecule, and the other Pt atom; the Pt-Pt bond is 2.5560(9) Angstrom in length. (C) 2003 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0277-5387(03)00097-4
• 作为产物：
  描述：

  potassium tetrachloroplatinate(II) 、 1,1'-二甲基-1H,1'H-[2,2']联咪唑 、 potassium iodide 以 水 为溶剂， 以64%的产率得到(1,1'-dimethyl-2,2'-biimidazole-N(3),N(3'))diiodiplatinum(II)
  参考文献：
  名称：

  Pd(II) and Pt(II) complexes of 2,2′-biimidazole and its N,N′-dimethyl derivative. The crystal structure of [{PtBr(DMSO)}2(Me2bim)] (Me2bim=N,N′-dimethyl-2,2′-biimidazole)

  摘要：

  The complexes [PdCl2(LL)] and [PtX2(LL)] [X = Cl, Br or I; LL = 2,2'-biimidazole (H(2)bim) or N,N'-dimethyl-2,2'-biimidazole (Me(2)bim)] were prepared and characterized spectroscopically. The effects of the chloro compounds on plasmid DNA conformation were studied by electrophoresis in agarose gels, and that of [PtCl2(H(2)bim)] on calf thymus DNA by circular dichroism spectroscopy. The observation that these effects were adversely affected by addition of DMSO (originally used with [PtCl2(Me(2)bim)], to improve its solubility) prompted a study of the solvolysis of [PtCl2(H(2)bim)] by this solvent. H-1 and Pt-195 NMR, and electrospray mass spectra, showed the solvolysis of both Pt-Cl and Pt-N bonds, the release of the ligand H2bim, and the formation of several polynuclear species. X-ray diffractometry of the dinuclear Pt(I) compound [{PtBr(DMSO)}(2)(Me(2)bim)] showed the ligand Me(2)bim to bridge through its non-methylated N atoms between two platinum atoms, the coordination spheres of which were each completed by a Br- ligand, the S atom of a DMSO molecule, and the other Pt atom; the Pt-Pt bond is 2.5560(9) Angstrom in length. (C) 2003 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0277-5387(03)00097-4

文献信息

• (1,1'-Dimethyl-2,2'-biimidazole-<i>N</i>³,<i>N</i>^3')diiodoplatinum(II)
  作者：J. S. Casas、A. Castiñeiras、Y. Parajó、J. Sordo、J. M. Varela

  DOI：10.1107/s0108270198009950

  日期：1998.12.15

  The title compound, [PtI2(C8H10N4)], exhibits square-planar cis coordination of the Pt atom to the two I atoms [mean Pt-I distance = 2.587(6)Angstrom] and the two unmethylated imidazole N atoms [mean Pt-N distance = 2.020(6)Angstrom], Successively antiparallel near-planar [PtI2(C8H10N4)] units form zigzag chains along the b axis, with Pt ... Pt distances longer than the interplanar spacing.