Pyrrolobenzimidazoles, processes for the preparation thereof and pharmaceutical compositions thereof for the treatment of coronary insufficiencies, cardiac failure, blood circulatory disturbances and occlusive diseases. The new pyrrolobenzimidazoles are of the formula ##STR1## wherein R.sub.1 is hydrogen, alkyl, alkenyl or cycloalkyl, R.sub.2 is hydrogen, alkyl, alkenyl, cyano or a substituted carbonyl or R.sub.1 and R.sub.2 together represent cycloalkylene or form alkylidene or cycloalkylidene, X is a valency bond, C.sub.1 -C.sub.4 alkylene or vinylene, T is oxygen or sulphur and Py is pyridyl or substituted pyridyl and including the tautomers thereof and the physiologically acceptable salts thereof.
吡咯并
咪唑类化合物,其制备方法以及用于治疗冠状动脉不足、心力衰竭、血液循环障碍和闭塞性疾病的药物组合物。新的
吡咯并
咪唑类化合物的结构式为##STR1##其中R.sub.1为氢、烷基、烯基或环烷基,R.sub.2为氢、烷基、烯基、
氰基或取代的羰基,或R.sub.1和R.sub.2一起代表环烷基或形成烷基亚甲基或环烷基亚甲基,X为价键,C.sub.1-C.sub.4烷基或
乙烯基,T为氧或
硫,Py为
吡啶基或取代的
吡啶基,包括其互变异构体和生理上可接受的盐。