1,3-dicyclohexyl-3-hydroxy-1-propanone | 92976-06-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1,3-dicyclohexyl-3-hydroxy-1-propanone
• 英文别名: 1,3-Dicyclohexyl-3-hydroxypropan-1-one
• CAS: 92976-06-2；77486-16-9
• 化学式: C₁₅H₂₆O₂
• 分子量: 238.37
• InChiKey: PVGIWHIGPVINJR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1,3-dicyclohexyl-3-hydroxy-1-propanone 在 sodium tetrahydroborate 、 1-hydroxy-6,8-diphenyl-1,2,3,4-tetrahydro-2-oxa-1-boranaphthalene 作用下， 生成 (S,R)-1,3-dicyclohexyl-1,3-propanediol
  参考文献：
  名称：

  在三联苯硼酸的帮助下将β-羟基酮立体选择性还原为1,3-二醇

  摘要：

  1-Hydroxy-6,8-diphenyl-1,2,3,4-tetrahydro-2-oxa-1-boranaphthalene（三联苯硼酸 1）用于立体选择性还原无环和环状 β-羟基酮。三联苯硼酸 1 和无环 β-羟基酮 2 通过共沸去除水转化为相应的硼酸酯。所得硼酸酯用还原剂原位处理以几乎完全得到syn 1,3-二醇3。抗 α-取代的 β-羟基酮 8 也被还原以立体选择性地产生抗、抗 1,3-二醇 9。此外，3-羟基-1-环戊酮的还原以高选择性得到顺式二醇11。

  DOI：

  10.1246/cl.1996.539
• 作为产物：
  描述：

  C₁₅H₂₅NO 在 copper(II) choride dihydrate 、 氢化铝 作用下， 以 甲醇 、 水 为溶剂， 以89%的产率得到1,3-dicyclohexyl-3-hydroxy-1-propanone
  参考文献：
  名称：

  铝和氯化铜将非共轭Δ²-异恶唑啉还原环裂解为β-羟基酮

  摘要：

  已经开发出一种容易，经济和有效的方案，该方案使用Al / CuCl 2作为还原剂将非共轭的Δ2-异恶唑啉还原成相应的β-羟基酮。该方法既快速又完整，只需不到十分钟即可完成总的环裂解。这是在有机合成中使用原位制备的Al / Cu对的第一个示例。 还原-异恶唑啉-β-羟基酮-铝/铜对

  DOI：

  10.1055/s-0031-1290310

文献信息

• Stereoselective reduction of β hydroxyketones to 1,3-diols highly selective 1,3-asymmetric induction via boron chelates
  作者：Koichi Narasaka、Fong-Chang Pai

  DOI：10.1016/0040-4020(84)80006-x

  日期：1984.1

  Highly selective asymmetric induction can be achieved in the reduction of acyclic β-hydroxyketones via boron chelates. Treatment of β-hydroxyketones (1) with tributyl or tri-isobutylborane and successively with sodium borohydride afforded syn-1,3-diols (3) in highly stereo-selective manner, Syn -α-substituted-β -hydroxyketones (8) were also reduced to give syn, syn-1,3-diols (9) exclusively. The reaction

  通过硼螯合物还原无环β-羟基酮可以实现高度选择性的不对称诱导。β羟基酮的治疗（1）用三丁基-或三- isobutylborane和依次用硼氢化钠，得到顺式-1,3-二醇（3在高度立体选择性的方式），Syn的-α取代-β-hydroxyketones（8）为也还原为仅生成syn，syn -1,3-二醇（9）。该反应进一步用于方便地制备3-脱氧己糖。
• STEREOSELECTIVE SYNTHESIS OF<i>MESO</i>(OR<i>ERYTHRO</i>) 1,3-DIOLS FROM β-HYDROXYKETONES
  作者：Koichi Narasaka、Hong Chang Pai

  DOI：10.1246/cl.1980.1415

  日期：1980.11.5

  Meso(or erythro) 1,3-diols are prepared in high stereoselectivity from β-hydroxyketones by the treatment with tributylborane and the successive reduction with sodium borohydride.

  通过三丁基硼烷处理和硼氢化钠的连续还原，可以从 β-羟基酮制备出具有高度立体选择性的中间（或赤基）1,3-二醇。
• PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, METAL COMPLEX DYE, DYE SOLUTION, DYE-ABSORBED ELECTRODE, AND METHOD FOR MANUFACTURING DYE-SENSITIZED SOLAR CELL
  申请人：Fujifilm Corporation

  公开号：EP2933875A1

  公开（公告）日：2015-10-21

  A photoelectric conversion element including an electrically conductive support, a photoconductor layer containing an electrolyte, a charge transfer layer containing an electrolyte, and a counter electrode, wherein the photoconductor layer contains semiconductor fine particles carrying a metal complex dye represented by Formula (I); a metal complex dye, a dye solution, a dye-adsorbed electrode, a dye-sensitized solar cell, and a method for producing dye-sensitized solar cell:         M(LD)(LA)·(CI)     Formula(I) wherein, in the formula, M represents a metal ion; LD represents a tridentate ligand represented by formulas (DL-1) to (DL-4); LA represents a specific tridentate ligand; and CI represents a counter ion to neutralize an electric charge: Y1 and Y2 represent an oxygen atom, a sulfur atom, a substituted or unsubstituted nitrogen atom, or a substituted or unsubstituted phosphorus atom; the rings AD and BD represent a hydrocarbon ring or a hetero ring; L represents a linking group represented by the following formulas (L-1) to (L-4); and Ra and Rb each independently represent a substituent, X represents a nitrogen atom or a carbon atom; the ring CD represents a nitrogen-containing hetero ring; T represents -O-, -S-, -NRL2- or -PRL3-; RL1 to RL3 represent a hydrogen atom or a substituent; and Alk represents an alkylene group.

  一种光电转换元件，包括导电支架、含有电解质的光电导层、含有电解质的电荷转移层和对电极，其中光电导层含有携带由式（I）表示的金属络合染料的半导体微粒；一种金属络合染料、一种染料溶液、一种染料吸附电极、一种染料敏化太阳能电池和一种生产染料敏化太阳能电池的方法： M(LD)(LA)-(CI) 式(I) 式中，M 代表金属离子；LD 代表由式（DL-1）至（DL-4）表示的三叉配体；LA 代表特定的三叉配体；CI 代表用于中和电荷的反离子： Y1 和 Y2 代表氧原子、硫原子、取代或未取代的氮原子或取代或未取代的磷原子；环 AD 和 BD 代表烃环或杂环；L 代表由下列式子（L-1）至（L-4）表示的连接基团；Ra 和 Rb 各自独立地代表取代基、 X 代表氮原子或碳原子；环 CD 代表含氮杂环；T 代表-O-、-S-、-NRL2-或-PRL3-；RL1 至 RL3 代表氢原子或取代基；Alk 代表亚烷基。
• Non-toxic corrosion-protection pigments based on manganese
  申请人：——

  公开号：US20040011252A1

  公开（公告）日：2004-01-22

  Corrosion-inhibiting pigments based on manganese are described that contain a trivalent or tetravalent manganese/valence stabilizer complex. An inorganic or organic material is used to stabilize the trivalent or tetravalent manganese ion to form a compound that is sparingly soluble, exhibits low solubility, or is insoluble in water, depending upon the intended usage. Specific stabilizers are chosen to control the release rate of trivalent or tetravalent manganese during exposure to water and to tailor the compatibility of the powder when used as a pigment in a chosen binder system. Stabilizers may also modify the processing and handling characteristics of the formed powders. Manganese/valence stabilizer combinations are chosen based on the well-founded principles of manganese coordination chemistry. Many manganese-valence stabilizer combinations are presented that can equal the performance of conventional hexavalent chromium or tetravalent lead systems. It is emphasized that this abstract is provided to comply with the rules requiring an abstract which will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims.

  以锰为基础的缓蚀颜料含有三价或四价锰/价稳定剂复合物。一种无机或有机材料可用于稳定三价或四价锰离子，从而形成一种可少量溶解、溶解度低或不溶于水的化合物，具体取决于预期用途。选择特定的稳定剂是为了控制三价锰或四价锰在遇水时的释放率，并调整粉末在所选粘合剂体系中用作颜料时的相容性。稳定剂还可以改变成型粉末的加工和处理特性。锰/价稳定剂组合的选择是基于锰配位化学的基本原理。文中介绍了许多锰价稳定剂组合，其性能与传统的六价铬或四价铅体系相当。需要强调的是，提供本摘要是为了符合要求提供摘要的规则，以便检索者或其他读者快速确定技术公开的主题。提交本摘要的前提是，本摘要不用于解释或限制权利要求的范围或含义。
• Non-toxic corrosion-protection pigments based on rare earth elements
  申请人：——

  公开号：US20040104377A1

  公开（公告）日：2004-06-03

  A corrosion-inhibiting pigment comprising a rare earth element and a valence stabilizer combinded to form a rare earth/valence stabilizer complex. The rare earth element is selected from cerium, terbium, praseodymium, or a combination thereof, and at least one rare earth element is in the tetravalent oxidation state. An inorganic or organic material is used to stabilize the tetravalent rare earth ion to form a compound that is sparingly soluble in water. Specific stabilizers are chosen to control the release rate of tetravalent cerium, terbium, or praseodymium during exposure to water and to tailor the compatibility of the powder when used as a pigment in a chosen binder system. Stabilizers may also modify the processing and handling characteristics of the formed powders. Many rare earth-valence stabilizer combinations are presented that can equal the performance of conventional hexavalent chromium systems.

  一种缓蚀颜料，由稀土元素和价态稳定剂结合形成稀土/价态稳定剂复合物。稀土元素选自铈、铽、镨或它们的组合，至少有一种稀土元素处于四价氧化态。使用无机或有机材料来稳定四价稀土离子，以形成稀溶于水的化合物。选择特定的稳定剂是为了控制四价铈、铽或镨在遇水时的释放率，并调整粉末在所选粘合剂体系中用作颜料时的相容性。稳定剂还可以改变成型粉末的加工和处理特性。本文介绍了许多稀土-价稳定剂组合，其性能可与传统的六价铬体系媲美。